TBI-p-2014-17
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Titel:
Design of Transcription Regulating Riboswitches
Author(s):
Findeiß S, Wachsmuth M, Mörl M and Stadler PF
submitted to:
Abstract:
In this chapter we review both computational and experimental aspects of de
novo RNA sequence design. We give an overview of currently available design
software and their limitations, and discuss the necessary setup to experimentally
validate proper function in vitro and in vivo. We focus on transcription regu-
lating riboswitches, a task that has just recently lead to first successful designs
of such RNA elements.
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