TBI-Preprint 05-10-001
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Titel:
Local Base Pairing Probabilities in Large RNAs
Author(s):
Stephan Bernhart, Ivo L. Hofacker, Peter F. Stadler
Submitted to:
Bioinformatics
Abstract:
The genome-wide search for non-coding RNAs requires efficient methods to compute and compare local secondary structures. Since the exact boundaries of such putative transcripts are typically unknown, arbitrary sequence windows have to be used in practice. Here we present a method for robustly computing the probabilities of local base pairs from long RNA sequences independent of the exact positions of the sequence window.
Keywords:
RNA secondary structure,
folding algorithms,
base pair probabilities
Alternative Numbers:
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Last modified: 2005-10-31 01:25:50 ivo