Praktikum zur Bioinformatik der Nukleinsäuren

4 stündiges Blockpraktikum.
Ziel ist die selbstständige Durchführung eines kleinen Forschungsprojekts aus dem Bereich der RNA Bioinformatik.

Ort: Computer-Praktikumsraum des Inst. f. Theoret. Chemie,
Rennweg 95b, 1030 Wien EINGANG: Dr. Bohrg. 7, großes Gebäude im Hof.

Thema 2009:

Bacterial small RNAs and their targets

Bacterial genomes encode not only protein coding genes, but also a noncoding RNAs, typically of around 50 to 500 nt in length, called small RNAs. These small RNAs perform regulatory functions, in most cases by binding mRNAs and thereby regulating transcription, translation, or mRNA stability.

A crucial step towords understanding the function of small RNAs is therefore to identify their mRNA targets. We will therefore perform target predictions for bacterial small RNAs using recently developed methods.

Literatur

Bacterial RNA review by Gottesman
Our own paper small RNA target prediction

Data Files and Instructions

Short outline of tasks
Directory with data files

Last modified: 2010-03-03 08:46:00 ivo