Simulation of SBML model
bhalla_02pool.xml

Results

Simulation end time: 3600 seconds;
Animated within: 90 seconds.

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Jacobian Matrix
Reaction Network
bioLog Interactions (only available with additional index + interaction file)

Protein interactions

generated automatically from interaction file

PDGF enzymatically (b) activates PDGFR;
internalization enzymatically inhibits PDGFR;
PDGFR enzymatically (b+p) activates SHC;
SHC enzymatically (b) activates Grb2;
Grb2 enzymatically (b) activates SOS;
PKC enzymatically (p) activates GEF;
PKC enzymatically (p) inhibits GAP;
SOS enzymatically (GDPexchange) activates Ras;
GEF enzymatically (GDPexchange) activates Ras;
GAP enzymatically (GTPhydrolysis) inhibits Ras;
Ras enzymatically (GTPhydrolysis) inhibits Ras;
PKC enzymatically (p) activates Raf;
ERK enzymatically (p) inhibits Raf;
PP2A enzymatically (2dep) inhibits Raf;
Ras enzymatically (b) activates Raf;
Raf enzymatically (2p) activates MEK;
PP2A enzymatically (2dep) inhibits MEK;
MEK enzymatically (2p) activates ERK;
ERK enzymatically (2p) inhibits MKP1;
ubiquitination enzymatically (deg) consumes MKP1
;
MKP1 enzymatically (2dep) inhibits ERK;
MKP2 enzymatically (2dep) inhibits ERK;
ERK enzymatically (loc) activates nuclear_ERK;
nuclear_ERK enzymatically (TS) activates MKP1_RNA;
MKP1_RNA enzymatically (loc/TL) activates MKP1;
ERK enzymatically (p) activates PLA2;
ERK enzymatically (p) activates SOS;
Ca enzymatically (b) activates PLA2;
DAG enzymatically (b) activates PLA2;
PIP2 enzymatically (b) activates PLA2;
PP2A enzymatically (dep) inhibits PLA2;
PLA2 enzymatically (lip) consumes APC;
PLA2 enzymatically (lip) activates AA;
AA enzymatically (b) activates PKC;
DAG enzymatically (b) activates PKC;
Ca enzymatically (b) activates PKC;

activates: PDGF binds to PDGFR
PDGF -> PDGFR: b
inhibits: internalization binds to PDGFR
activates: PDGFR binds to SHC
PDGFR phosphorylates SHC
activates: SHC binds to Grb2
SHC -> Grb2: b
activates: Grb2 binds to SOS
Grb2 -> SOS: b
activates: PKC binds to GEF
PKC phosphorylates GEF
inhibits: PKC binds to GAP
PKC phosphorylates GAP
activates: SOS binds to Ras
SOS -> Ras: GDPexchange
activates: GEF binds to Ras
GEF -> Ras: GDPexchange
inhibits: GAP binds to Ras
GAP -> Ras: GTPhydrolysis
inhibits: Ras binds to Ras
Ras -> Ras: GTPhydrolysis
activates: PKC binds to Raf
PKC phosphorylates Raf
inhibits: ERK binds to Raf
ERK phosphorylates Raf
inhibits: PP2A binds to Raf
PP2A phosphorylates Raf
activates: Ras binds to Raf
Ras -> Raf: b
activates: Raf binds to MEK
Raf phosphorylates MEK 2 times
inhibits: PP2A binds to MEK
PP2A phosphorylates MEK
activates: MEK binds to ERK
MEK phosphorylates ERK 2 times
inhibits: ERK binds to MKP1
ERK phosphorylates MKP1 2 times
consumes: ubiquitination binds to MKP1

ubiquitination -> MKP1
: deg
inhibits: MKP1 binds to ERK
MKP1 phosphorylates ERK
inhibits: MKP2 binds to ERK
MKP2 phosphorylates ERK
activates: ERK binds to nuclear_ERK
ERK -> nuclear_ERK: loc
activates: nuclear_ERK binds to MKP1_RNA
nuclear_ERK -> MKP1_RNA: TS
activates: MKP1_RNA binds to MKP1
MKP1_RNA -> MKP1: loc
MKP1_RNA -> MKP1: TL
activates: ERK binds to PLA2
ERK phosphorylates PLA2
activates: ERK binds to SOS
ERK phosphorylates SOS
activates: Ca binds to PLA2
Ca -> PLA2: b
activates: DAG binds to PLA2
DAG -> PLA2: b
activates: PIP2 binds to PLA2
PIP2 -> PLA2: b
inhibits: PP2A binds to PLA2
PP2A phosphorylates PLA2
consumes: PLA2 binds to APC
PLA2 phosphorylates APC
activates: PLA2 binds to AA
PLA2 phosphorylates AA
activates: AA binds to PKC
AA -> PKC: b
activates: DAG binds to PKC
DAG -> PKC: b
activates: Ca binds to PKC
Ca -> PKC: b

Model details


Model Statistics:
Model id: bhalla_02_Fig1b
Model name: (not set)

Compartments: 1
Species: 96
Reactions: 103
Rules: 2
Events: 0
Functions: 0


# Initial Conditions for Species and Compartments:
# Compartments:
c = 1; dimensions 3;
# Species concentrations in `compartment' c
GDP_Ras_Shc_a_Sos_Grb2 = 0;
craf_1_PKC_a_pool = 0;
GAP_PKC_a_pool = 0;
inact_GEF_PKC_a_pool = 0;
craf_1_a_MAPK_a = 0;
PLA2_cytosolic_MAPK_a = 0;
MKP_1_MAPK_a = 0;
MKP_1_ser359_a_MAPK_a = 0;
MAPK_tyr_MKP_1 = 0;
MAPK_a_MKP_1 = 0;
craf_1_a_PPhosphatase2A = 0;
MAPKK_a_PPhosphatase2A = 0;
MAPKK_ser_PPhosphatase2A = 0;
craf_1_a_a_PPhosphatase2A = 0;
MAPK_tyr_MKP_2 = 0;
MAPK_a_MKP_2 = 0;
Shc_a_Sos_Grb2 = 0;
DAG = 11.661; constant;
Ca = 0.08; constant;
AA = 6.12;
MAPK_a = 0;
MKP_1 = 0.0004;
PPhosphatase2A = 0.224;
temp_PIP2 = 2.5; constant;
tot_MKP1 = 0;
MKP_2 = 0.002;
Sos_a_Grb2 = 0;
Grb2 = 1;
Sos_Grb2 = 0;
Sos_a = 0;
Sos = 0.1;
PKC_a_pool = 0; boundary;
PKC_Ca = 3.7208e-17;
PKC_DAG_AA_a = 4.9137e-18;
PKC_Ca_AA_a = 1.75e-16;
PKC_Ca_memb_a = 1.3896e-17;
PKC_DAG_memb_a = 9.4352e-21;
PKC_basal_a = 0.02;
PKC_AA_a = 1.8133e-17;
PKC_Ca_DAG = 8.4632e-23;
PKC_DAG = 1.161e-16;
PKC_DAG_AA = 2.5188e-19;
PKC_cytosolic = 1;
MAPK_MAPKK_a = 0;
MAPK_tyr_MAPKK_a = 0;
MAPKK_Raf_GTP_Ras_a = 0;
MAPKK_ser_Raf_GTP_Ras_a = 0;
MAPKK_RGR = 0;
MAPKK_ser_RGR = 0;
MAPK_tyr_MKP_1_a_a = 0;
MAPK_a_MKP_1_a_a = 0;
Nucleotides_nuc_MAPK_a = 0;
craf_1 = 0.2;
craf_1_a = 0;
MAPKK = 0.18;
MAPK = 0.36;
craf_1_a_a = 0;
MAPK_tyr = 0;
MAPKK_a = 0;
MAPKK_ser = 0;
Raf_GTP_Ras_a = 0;
RGR = 0;
Ubiquitination = 0;
MKP_1_ser359_a = 0;
MKP_1_a_a = 0;
nuc_MAPK_a = 0;
MKP1_RNA = 0.0001;
Nucleotides = 0.1; constant;
APC_PLA2_Ca_a = 0;
APC_PIP2_PLA2_a = 0;
APC_PIP2_Ca_PLA2_a = 0;
APC_DAG_Ca_PLA2_a = 0;
APC_PLA2_a_Ca = 0;
PLA2_cytosolic = 0.4;
PLA2_Ca_a = 0;
PIP2_PLA2_a = 0;
PIP2_Ca_PLA2_a = 0;
DAG_Ca_PLA2_a = 0;
APC = 30; constant;
PLA2_a_Ca = 0;
PLA2_a = 0;
GDP_Ras_GEF_a = 0;
GTP_Ras_GAP = 0;
inact_GEF = 0.1;
GEF_a = 0;
GTP_Ras = 0;
GDP_Ras = 0.2;
GAP_a = 0;
GAP = 0.002;
SHC_L_PDGFR = 0;
PDGFR = 0.10833;
L_PDGFR = 0;
PDGF = 0.0015; boundary;
SHC = 0.5;
SHC_a = 0;
Internal_L_PDGFR = 0;


# Reactions:
r1: craf_1_a + GTP_Ras <-> Raf_GTP_Ras_a; Kf * craf_1_a * GTP_Ras - Kb * Raf_GTP_Ras_a; kf = 0.0001; kb = 0.5; Kf = 60; Kb = 0.5;
r2: craf_1 + GTP_Ras <-> RGR; Kf * craf_1 * GTP_Ras - Kb * RGR; kf = 1e-05; kb = 1; Kf = 6; Kb = 1;
r3a: GDP_Ras + Shc_a_Sos_Grb2 <-> GDP_Ras_Shc_a_Sos_Grb2; k1 * GDP_Ras * Shc_a_Sos_Grb2 - k2 * GDP_Ras_Shc_a_Sos_Grb2; k1 = 0.198; k2 = 0.08;
r3b: GDP_Ras_Shc_a_Sos_Grb2 <-> Shc_a_Sos_Grb2 + GTP_Ras; k3 * GDP_Ras_Shc_a_Sos_Grb2; k3 = 0.02;
r4a: craf_1 + PKC_a_pool <-> craf_1_PKC_a_pool; k1 * craf_1 * PKC_a_pool - k2 * craf_1_PKC_a_pool; k1 = 0.3; k2 = 16;
r4b: craf_1_PKC_a_pool <-> PKC_a_pool + craf_1_a; k3 * craf_1_PKC_a_pool; k3 = 4;
r10a: GAP + PKC_a_pool <-> GAP_PKC_a_pool; k1 * GAP * PKC_a_pool - k2 * GAP_PKC_a_pool; k1 = 1.875; k2 = 100;
r10b: GAP_PKC_a_pool <-> PKC_a_pool + GAP_a; k3 * GAP_PKC_a_pool; k3 = 25;
r16a: inact_GEF + PKC_a_pool <-> inact_GEF_PKC_a_pool; k1 * inact_GEF * PKC_a_pool - k2 * inact_GEF_PKC_a_pool; k1 = 0.3; k2 = 16;
r16b: inact_GEF_PKC_a_pool <-> PKC_a_pool + GEF_a; k3 * inact_GEF_PKC_a_pool; k3 = 4;
r22a: craf_1_a + MAPK_a <-> craf_1_a_MAPK_a; k1 * craf_1_a * MAPK_a - k2 * craf_1_a_MAPK_a; k1 = 1.95; k2 = 40;
r22b: craf_1_a_MAPK_a <-> MAPK_a + craf_1_a_a; k3 * craf_1_a_MAPK_a; k3 = 10;
r23a: PLA2_cytosolic + MAPK_a <-> PLA2_cytosolic_MAPK_a; k1 * PLA2_cytosolic * MAPK_a - k2 * PLA2_cytosolic_MAPK_a; k1 = 3.9; k2 = 80;
r23b: PLA2_cytosolic_MAPK_a <-> MAPK_a + PLA2_a; k3 * PLA2_cytosolic_MAPK_a; k3 = 20;
r24a: MKP_1 + MAPK_a <-> MKP_1_MAPK_a; k1 * MKP_1 * MAPK_a - k2 * MKP_1_MAPK_a; k1 = 0.195; k2 = 4;
r24b: MKP_1_MAPK_a <-> MAPK_a + MKP_1_ser359_a; k3 * MKP_1_MAPK_a; k3 = 1;
r25a: MKP_1_ser359_a + MAPK_a <-> MKP_1_ser359_a_MAPK_a; k1 * MKP_1_ser359_a * MAPK_a - k2 * MKP_1_ser359_a_MAPK_a; k1 = 0.195; k2 = 4;
r25b: MKP_1_ser359_a_MAPK_a <-> MAPK_a + MKP_1_a_a; k3 * MKP_1_ser359_a_MAPK_a; k3 = 1;
r26a: MAPK_tyr + MKP_1 <-> MAPK_tyr_MKP_1; k1 * MAPK_tyr * MKP_1 - k2 * MAPK_tyr_MKP_1; k1 = 74.999; k2 = 4;
r26b: MAPK_tyr_MKP_1 <-> MKP_1 + MAPK; k3 * MAPK_tyr_MKP_1; k3 = 1;
r27a: MAPK_a + MKP_1 <-> MAPK_a_MKP_1; k1 * MAPK_a * MKP_1 - k2 * MAPK_a_MKP_1; k1 = 74.999; k2 = 4;
r27b: MAPK_a_MKP_1 <-> MKP_1 + MAPK_tyr; k3 * MAPK_a_MKP_1; k3 = 1;
r28a: craf_1_a + PPhosphatase2A <-> craf_1_a_PPhosphatase2A; k1 * craf_1_a * PPhosphatase2A - k2 * craf_1_a_PPhosphatase2A; k1 = 1.98; k2 = 25.0002;
r28b: craf_1_a_PPhosphatase2A <-> PPhosphatase2A + craf_1; k3 * craf_1_a_PPhosphatase2A; k3 = 6;
r29a: MAPKK_a + PPhosphatase2A <-> MAPKK_a_PPhosphatase2A; k1 * MAPKK_a * PPhosphatase2A - k2 * MAPKK_a_PPhosphatase2A; k1 = 1.98; k2 = 25.0002;
r29b: MAPKK_a_PPhosphatase2A <-> PPhosphatase2A + MAPKK_ser; k3 * MAPKK_a_PPhosphatase2A; k3 = 6;
r30a: MAPKK_ser + PPhosphatase2A <-> MAPKK_ser_PPhosphatase2A; k1 * MAPKK_ser * PPhosphatase2A - k2 * MAPKK_ser_PPhosphatase2A; k1 = 1.98; k2 = 25.0002;
r30b: MAPKK_ser_PPhosphatase2A <-> PPhosphatase2A + MAPKK; k3 * MAPKK_ser_PPhosphatase2A; k3 = 6;
r31a: craf_1_a_a + PPhosphatase2A <-> craf_1_a_a_PPhosphatase2A; k1 * craf_1_a_a * PPhosphatase2A - k2 * craf_1_a_a_PPhosphatase2A; k1 = 1.98; k2 = 25.0002;
r31b: craf_1_a_a_PPhosphatase2A <-> PPhosphatase2A + craf_1_a; k3 * craf_1_a_a_PPhosphatase2A; k3 = 6;
r32a: MAPK_tyr + MKP_2 <-> MAPK_tyr_MKP_2; k1 * MAPK_tyr * MKP_2 - k2 * MAPK_tyr_MKP_2; k1 = 74.999; k2 = 4;
r32b: MAPK_tyr_MKP_2 <-> MKP_2 + MAPK; k3 * MAPK_tyr_MKP_2; k3 = 1;
r33a: MAPK_a + MKP_2 <-> MAPK_a_MKP_2; k1 * MAPK_a * MKP_2 - k2 * MAPK_a_MKP_2; k1 = 74.999; k2 = 4;
r33b: MAPK_a_MKP_2 <-> MKP_2 + MAPK_tyr; k3 * MAPK_a_MKP_2; k3 = 1;
r34: Sos_Grb2 + SHC_a <-> Shc_a_Sos_Grb2; Kf * Sos_Grb2 * SHC_a - Kb * Shc_a_Sos_Grb2; kf = 8.333e-07; kb = 0.1; Kf = 0.49998; Kb = 0.1;
r35: Sos_a + Grb2 <-> Sos_a_Grb2; Kf * Sos_a * Grb2 - Kb * Sos_a_Grb2; kf = 4.1667e-08; kb = 0.0168; Kf = 0.025; Kb = 0.0168;
r36: Sos_a <-> Sos; Kf * Sos_a - Kb * Sos; kf = 0.001; kb = 0; Kf = 0.001; Kb = 0;
r37: Grb2 + Sos <-> Sos_Grb2; Kf * Grb2 * Sos - Kb * Sos_Grb2; kf = 4.1667e-08; kb = 0.0168; Kf = 0.025; Kb = 0.0168;
r38: PKC_cytosolic + Ca <-> PKC_Ca; Kf * PKC_cytosolic * Ca - Kb * PKC_Ca; kf = 1e-06; kb = 0.5; Kf = 0.6; Kb = 0.5;
r39: DAG + PKC_Ca <-> PKC_Ca_DAG; Kf * DAG * PKC_Ca - Kb * PKC_Ca_DAG; kf = 1.3333e-08; kb = 8.6348; Kf = 0.0079998; Kb = 8.6348;
r40: PKC_Ca <-> PKC_Ca_memb_a; Kf * PKC_Ca - Kb * PKC_Ca_memb_a; kf = 1.2705; kb = 3.5026; Kf = 1.2705; Kb = 3.5026;
r41: PKC_Ca_DAG <-> PKC_DAG_memb_a; Kf * PKC_Ca_DAG - Kb * PKC_DAG_memb_a; kf = 1; kb = 0.1; Kf = 1; Kb = 0.1;
r42: PKC_Ca + AA <-> PKC_Ca_AA_a; Kf * PKC_Ca * AA - Kb * PKC_Ca_AA_a; kf = 2e-09; kb = 0.1; Kf = 0.0012; Kb = 0.1;
r43: PKC_DAG_AA <-> PKC_DAG_AA_a; Kf * PKC_DAG_AA - Kb * PKC_DAG_AA_a; kf = 2; kb = 0.2; Kf = 2; Kb = 0.2;
r44: PKC_cytosolic <-> PKC_basal_a; Kf * PKC_cytosolic - Kb * PKC_basal_a; kf = 1; kb = 50; Kf = 1; Kb = 50;
r45: AA + PKC_cytosolic <-> PKC_AA_a; Kf * AA * PKC_cytosolic - Kb * PKC_AA_a; kf = 2e-10; kb = 0.1; Kf = 0.00012; Kb = 0.1;
r46: PKC_cytosolic + DAG <-> PKC_DAG; Kf * PKC_cytosolic * DAG - Kb * PKC_DAG; kf = 1e-09; kb = 0.1; Kf = 0.0006; Kb = 0.1;
r47: PKC_DAG + AA <-> PKC_DAG_AA; Kf * PKC_DAG * AA - Kb * PKC_DAG_AA; kf = 3e-08; kb = 2; Kf = 0.018; Kb = 2;
r48: MKP_1 <-> Ubiquitination; Kf * MKP_1 - Kb * Ubiquitination; kf = 0.00037; kb = 0; Kf = 0.00037; Kb = 0;
r49: MKP_1_a_a <-> Ubiquitination; Kf * MKP_1_a_a - Kb * Ubiquitination; kf = 0.0001; kb = 0; Kf = 0.0001; Kb = 0;
r50: MKP_1_ser359_a <-> Ubiquitination; Kf * MKP_1_ser359_a - Kb * Ubiquitination; kf = 0.0001; kb = 0; Kf = 0.0001; Kb = 0;
r51: MKP_1_ser359_a <-> MKP_1; Kf * MKP_1_ser359_a - Kb * MKP_1; kf = 0.0001; kb = 0; Kf = 0.0001; Kb = 0;
r52: MKP_1_a_a <-> MKP_1_ser359_a; Kf * MKP_1_a_a - Kb * MKP_1_ser359_a; kf = 0.0001; kb = 0; Kf = 0.0001; Kb = 0;
r53: 2 MAPK_a <-> nuc_MAPK_a; Kf * pow(MAPK_a, 2) - Kb * nuc_MAPK_a; kf = 1.6667e-08; kb = 0.005; Kf = 0.01; Kb = 0.005;
r54: MKP1_RNA <-> MKP_1; Kf * MKP1_RNA - Kb * MKP_1; kf = 0.002; kb = 0; Kf = 0.002; Kb = 0;
r55: Nucleotides <-> MKP1_RNA; Kf * Nucleotides - Kb * MKP1_RNA; kf = 5e-06; kb = 0; Kf = 5e-06; Kb = 0;
r56a: MAPK + MAPKK_a <-> MAPK_MAPKK_a; k1 * MAPK * MAPKK_a - k2 * MAPK_MAPKK_a; k1 = 16.2; k2 = 0.6;
r56b: MAPK_MAPKK_a <-> MAPKK_a + MAPK_tyr; k3 * MAPK_MAPKK_a; k3 = 0.15;
r57a: MAPK_tyr + MAPKK_a <-> MAPK_tyr_MAPKK_a; k1 * MAPK_tyr * MAPKK_a - k2 * MAPK_tyr_MAPKK_a; k1 = 16.2; k2 = 0.6;
r57b: MAPK_tyr_MAPKK_a <-> MAPKK_a + MAPK_a; k3 * MAPK_tyr_MAPKK_a; k3 = 0.15;
r58a: MAPKK + Raf_GTP_Ras_a <-> MAPKK_Raf_GTP_Ras_a; k1 * MAPKK * Raf_GTP_Ras_a - k2 * MAPKK_Raf_GTP_Ras_a; k1 = 3.3; k2 = 0.42;
r58b: MAPKK_Raf_GTP_Ras_a <-> Raf_GTP_Ras_a + MAPKK_ser; k3 * MAPKK_Raf_GTP_Ras_a; k3 = 0.105;
r59a: MAPKK_ser + Raf_GTP_Ras_a <-> MAPKK_ser_Raf_GTP_Ras_a; k1 * MAPKK_ser * Raf_GTP_Ras_a - k2 * MAPKK_ser_Raf_GTP_Ras_a; k1 = 3.3; k2 = 0.42;
r59b: MAPKK_ser_Raf_GTP_Ras_a <-> Raf_GTP_Ras_a + MAPKK_a; k3 * MAPKK_ser_Raf_GTP_Ras_a; k3 = 0.105;
r60a: MAPKK + RGR <-> MAPKK_RGR; k1 * MAPKK * RGR - k2 * MAPKK_RGR; k1 = 3.3; k2 = 0.42;
r60b: MAPKK_RGR <-> RGR + MAPKK_ser; k3 * MAPKK_RGR; k3 = 0.105;
r61a: MAPKK_ser + RGR <-> MAPKK_ser_RGR; k1 * MAPKK_ser * RGR - k2 * MAPKK_ser_RGR; k1 = 3.3; k2 = 0.42;
r61b: MAPKK_ser_RGR <-> RGR + MAPKK_a; k3 * MAPKK_ser_RGR; k3 = 0.105;
r62a: MAPK_tyr + MKP_1_a_a <-> MAPK_tyr_MKP_1_a_a; k1 * MAPK_tyr * MKP_1_a_a - k2 * MAPK_tyr_MKP_1_a_a; k1 = 74.999; k2 = 4;
r62b: MAPK_tyr_MKP_1_a_a <-> MKP_1_a_a + MAPK; k3 * MAPK_tyr_MKP_1_a_a; k3 = 1;
r63a: MAPK_a + MKP_1_a_a <-> MAPK_a_MKP_1_a_a; k1 * MAPK_a * MKP_1_a_a - k2 * MAPK_a_MKP_1_a_a; k1 = 74.999; k2 = 4;
r63b: MAPK_a_MKP_1_a_a <-> MKP_1_a_a + MAPK_tyr; k3 * MAPK_a_MKP_1_a_a; k3 = 1;
r64a: Nucleotides + nuc_MAPK_a <-> Nucleotides_nuc_MAPK_a; k1 * Nucleotides * nuc_MAPK_a - k2 * Nucleotides_nuc_MAPK_a; k1 = 0.001; k2 = 0.0032;
r64b: Nucleotides_nuc_MAPK_a <-> nuc_MAPK_a + MKP1_RNA; k3 * Nucleotides_nuc_MAPK_a; k3 = 0.0008;
r65: PLA2_cytosolic + Ca <-> PLA2_Ca_a; Kf * PLA2_cytosolic * Ca - Kb * PLA2_Ca_a; kf = 1.6667e-06; kb = 0.1; Kf = 1; Kb = 0.1;
r66: temp_PIP2 + PLA2_cytosolic <-> PIP2_PLA2_a; Kf * temp_PIP2 * PLA2_cytosolic - Kb * PIP2_PLA2_a; kf = 2e-09; kb = 0.5; Kf = 0.0012; Kb = 0.5;
r67: temp_PIP2 + PLA2_Ca_a <-> PIP2_Ca_PLA2_a; Kf * temp_PIP2 * PLA2_Ca_a - Kb * PIP2_Ca_PLA2_a; kf = 2e-08; kb = 0.1; Kf = 0.012; Kb = 0.1;
r68: DAG + PLA2_Ca_a <-> DAG_Ca_PLA2_a; Kf * DAG * PLA2_Ca_a - Kb * DAG_Ca_PLA2_a; kf = 5e-09; kb = 4; Kf = 0.003; Kb = 4;
r69: AA <-> APC; Kf * AA - Kb * APC; kf = 0.4; kb = 0; Kf = 0.4; Kb = 0;
r70: PLA2_a + Ca <-> PLA2_a_Ca; Kf * PLA2_a * Ca - Kb * PLA2_a_Ca; kf = 1e-05; kb = 0.1; Kf = 6; Kb = 0.1;
r71: PLA2_a <-> PLA2_cytosolic; Kf * PLA2_a - Kb * PLA2_cytosolic; kf = 0.17; kb = 0; Kf = 0.17; Kb = 0;
r72a: APC + PLA2_Ca_a <-> APC_PLA2_Ca_a; k1 * APC * PLA2_Ca_a - k2 * APC_PLA2_Ca_a; k1 = 1.35; k2 = 21.6;
r72b: APC_PLA2_Ca_a <-> PLA2_Ca_a + AA; k3 * APC_PLA2_Ca_a; k3 = 5.4;
r73a: APC + PIP2_PLA2_a <-> APC_PIP2_PLA2_a; k1 * APC * PIP2_PLA2_a - k2 * APC_PIP2_PLA2_a; k1 = 2.76; k2 = 44.16;
r73b: APC_PIP2_PLA2_a <-> PIP2_PLA2_a + AA; k3 * APC_PIP2_PLA2_a; k3 = 11.04;
r74a: APC + PIP2_Ca_PLA2_a <-> APC_PIP2_Ca_PLA2_a; k1 * APC * PIP2_Ca_PLA2_a - k2 * APC_PIP2_Ca_PLA2_a; k1 = 9; k2 = 144;
r74b: APC_PIP2_Ca_PLA2_a <-> PIP2_Ca_PLA2_a + AA; k3 * APC_PIP2_Ca_PLA2_a; k3 = 36;
r75a: APC + DAG_Ca_PLA2_a <-> APC_DAG_Ca_PLA2_a; k1 * APC * DAG_Ca_PLA2_a - k2 * APC_DAG_Ca_PLA2_a; k1 = 15; k2 = 240;
r75b: APC_DAG_Ca_PLA2_a <-> DAG_Ca_PLA2_a + AA; k3 * APC_DAG_Ca_PLA2_a; k3 = 60;
r76a: APC + PLA2_a_Ca <-> APC_PLA2_a_Ca; k1 * APC * PLA2_a_Ca - k2 * APC_PLA2_a_Ca; k1 = 30; k2 = 480;
r76b: APC_PLA2_a_Ca <-> PLA2_a_Ca + AA; k3 * APC_PLA2_a_Ca; k3 = 120;
r77: GEF_a <-> inact_GEF; Kf * GEF_a - Kb * inact_GEF; kf = 0.1; kb = 0; Kf = 0.1; Kb = 0;
r78: GTP_Ras <-> GDP_Ras; Kf * GTP_Ras - Kb * GDP_Ras; kf = 0.0001; kb = 0; Kf = 0.0001; Kb = 0;
r79: GAP_a <-> GAP; Kf * GAP_a - Kb * GAP; kf = 0.1; kb = 0; Kf = 0.1; Kb = 0;
r80a: GDP_Ras + GEF_a <-> GDP_Ras_GEF_a; k1 * GDP_Ras * GEF_a - k2 * GDP_Ras_GEF_a; k1 = 0.198; k2 = 0.08;
r80b: GDP_Ras_GEF_a <-> GEF_a + GTP_Ras; k3 * GDP_Ras_GEF_a; k3 = 0.02;
r81a: GTP_Ras + GAP <-> GTP_Ras_GAP; k1 * GTP_Ras * GAP - k2 * GTP_Ras_GAP; k1 = 999.6; k2 = 1000;
r81b: GTP_Ras_GAP <-> GAP + GDP_Ras; k3 * GTP_Ras_GAP; k3 = 10;
r82: PDGFR + PDGF <-> L_PDGFR; Kf * PDGFR * PDGF - Kb * L_PDGFR; kf = 0.00033333; kb = 0.1; Kf = 200; Kb = 0.1;
r83: SHC_a <-> SHC; Kf * SHC_a - Kb * SHC; kf = 0.01; kb = 0; Kf = 0.01; Kb = 0;
r84: L_PDGFR <-> Internal_L_PDGFR; Kf * L_PDGFR - Kb * Internal_L_PDGFR; kf = 0.001; kb = 0.00066; Kf = 0.001; Kb = 0.00066;
r85a: SHC + L_PDGFR <-> SHC_L_PDGFR; k1 * SHC * L_PDGFR - k2 * SHC_L_PDGFR; k1 = 0.3; k2 = 0.2;
r85b: SHC_L_PDGFR <-> L_PDGFR + SHC_a; k3 * SHC_L_PDGFR; k3 = 0.05;
# Rules:
assignmentRule (scalar): PDGF = piecewise(geq(time, 300), 0, 0.0015)
assignmentRule (scalar): PKC_a_pool = PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a


# Derived system of Ordinary Differential Equations (ODEs):
# Parameters:
DAG = 11.661
Ca = 0.08
temp_PIP2 = 2.5
Nucleotides = 0.1
APC = 30
# ODEs:
1: dGDP_Ras_Shc_a_Sos_Grb2/dt = 0.198 * GDP_Ras * Shc_a_Sos_Grb2 - 0.08 * GDP_Ras_Shc_a_Sos_Grb2 - 0.02 * GDP_Ras_Shc_a_Sos_Grb2;
2: dcraf_1_PKC_a_pool/dt = 0.3 * craf_1 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a) - 16 * craf_1_PKC_a_pool - 4 * craf_1_PKC_a_pool;
3: dGAP_PKC_a_pool/dt = 1.875 * GAP * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a) - 100 * GAP_PKC_a_pool - 25 * GAP_PKC_a_pool;
4: dinact_GEF_PKC_a_pool/dt = 0.3 * inact_GEF * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a) - 16 * inact_GEF_PKC_a_pool - 4 * inact_GEF_PKC_a_pool;
5: dcraf_1_a_MAPK_a/dt = 1.95 * craf_1_a * MAPK_a - 40 * craf_1_a_MAPK_a - 10 * craf_1_a_MAPK_a;
6: dPLA2_cytosolic_MAPK_a/dt = 3.9 * PLA2_cytosolic * MAPK_a - 80 * PLA2_cytosolic_MAPK_a - 20 * PLA2_cytosolic_MAPK_a;
7: dMKP_1_MAPK_a/dt = 0.195 * MKP_1 * MAPK_a - 4 * MKP_1_MAPK_a - MKP_1_MAPK_a;
8: dMKP_1_ser359_a_MAPK_a/dt = 0.195 * MKP_1_ser359_a * MAPK_a - 4 * MKP_1_ser359_a_MAPK_a - MKP_1_ser359_a_MAPK_a;
9: dMAPK_tyr_MKP_1/dt = 74.999 * MAPK_tyr * MKP_1 - 4 * MAPK_tyr_MKP_1 - MAPK_tyr_MKP_1;
10: dMAPK_a_MKP_1/dt = 74.999 * MAPK_a * MKP_1 - 4 * MAPK_a_MKP_1 - MAPK_a_MKP_1;
11: dcraf_1_a_PPhosphatase2A/dt = 1.98 * craf_1_a * PPhosphatase2A - 25.0002 * craf_1_a_PPhosphatase2A - 6 * craf_1_a_PPhosphatase2A;
12: dMAPKK_a_PPhosphatase2A/dt = 1.98 * MAPKK_a * PPhosphatase2A - 25.0002 * MAPKK_a_PPhosphatase2A - 6 * MAPKK_a_PPhosphatase2A;
13: dMAPKK_ser_PPhosphatase2A/dt = 1.98 * MAPKK_ser * PPhosphatase2A - 25.0002 * MAPKK_ser_PPhosphatase2A - 6 * MAPKK_ser_PPhosphatase2A;
14: dcraf_1_a_a_PPhosphatase2A/dt = 1.98 * craf_1_a_a * PPhosphatase2A - 25.0002 * craf_1_a_a_PPhosphatase2A - 6 * craf_1_a_a_PPhosphatase2A;
15: dMAPK_tyr_MKP_2/dt = 74.999 * MAPK_tyr * MKP_2 - 4 * MAPK_tyr_MKP_2 - MAPK_tyr_MKP_2;
16: dMAPK_a_MKP_2/dt = 74.999 * MAPK_a * MKP_2 - 4 * MAPK_a_MKP_2 - MAPK_a_MKP_2;
17: dShc_a_Sos_Grb2/dt = -(0.198 * GDP_Ras * Shc_a_Sos_Grb2 - 0.08 * GDP_Ras_Shc_a_Sos_Grb2) + 0.02 * GDP_Ras_Shc_a_Sos_Grb2 + (0.49998 * Sos_Grb2 * SHC_a - 0.1 * Shc_a_Sos_Grb2);
18: dAA/dt = -(0.0012 * PKC_Ca * AA - 0.1 * PKC_Ca_AA_a) - (0.00012 * AA * PKC_cytosolic - 0.1 * PKC_AA_a) - (0.018 * PKC_DAG * AA - 2 * PKC_DAG_AA) - 0.4 * AA + 5.4 * APC_PLA2_Ca_a + 11.04 * APC_PIP2_PLA2_a + 36 * APC_PIP2_Ca_PLA2_a + 60 * APC_DAG_Ca_PLA2_a + 120 * APC_PLA2_a_Ca;
19: dMAPK_a/dt = -(1.95 * craf_1_a * MAPK_a - 40 * craf_1_a_MAPK_a) + 10 * craf_1_a_MAPK_a - (3.9 * PLA2_cytosolic * MAPK_a - 80 * PLA2_cytosolic_MAPK_a) + 20 * PLA2_cytosolic_MAPK_a - (0.195 * MKP_1 * MAPK_a - 4 * MKP_1_MAPK_a) + MKP_1_MAPK_a - (0.195 * MKP_1_ser359_a * MAPK_a - 4 * MKP_1_ser359_a_MAPK_a) + MKP_1_ser359_a_MAPK_a - (74.999 * MAPK_a * MKP_1 - 4 * MAPK_a_MKP_1) - (74.999 * MAPK_a * MKP_2 - 4 * MAPK_a_MKP_2) - 2 * (0.01 * pow(MAPK_a, 2) - 0.005 * nuc_MAPK_a) + 0.15 * MAPK_tyr_MAPKK_a - (74.999 * MAPK_a * MKP_1_a_a - 4 * MAPK_a_MKP_1_a_a);
20: dMKP_1/dt = -(0.195 * MKP_1 * MAPK_a - 4 * MKP_1_MAPK_a) - (74.999 * MAPK_tyr * MKP_1 - 4 * MAPK_tyr_MKP_1) + MAPK_tyr_MKP_1 - (74.999 * MAPK_a * MKP_1 - 4 * MAPK_a_MKP_1) + MAPK_a_MKP_1 - 0.00037 * MKP_1 + 0.0001 * MKP_1_ser359_a + 0.002 * MKP1_RNA;
21: dPPhosphatase2A/dt = -(1.98 * craf_1_a * PPhosphatase2A - 25.0002 * craf_1_a_PPhosphatase2A) + 6 * craf_1_a_PPhosphatase2A - (1.98 * MAPKK_a * PPhosphatase2A - 25.0002 * MAPKK_a_PPhosphatase2A) + 6 * MAPKK_a_PPhosphatase2A - (1.98 * MAPKK_ser * PPhosphatase2A - 25.0002 * MAPKK_ser_PPhosphatase2A) + 6 * MAPKK_ser_PPhosphatase2A - (1.98 * craf_1_a_a * PPhosphatase2A - 25.0002 * craf_1_a_a_PPhosphatase2A) + 6 * craf_1_a_a_PPhosphatase2A;
22: dtot_MKP1/dt = 0;
23: dMKP_2/dt = -(74.999 * MAPK_tyr * MKP_2 - 4 * MAPK_tyr_MKP_2) + MAPK_tyr_MKP_2 - (74.999 * MAPK_a * MKP_2 - 4 * MAPK_a_MKP_2) + MAPK_a_MKP_2;
24: dSos_a_Grb2/dt = 0.025 * Sos_a * Grb2 - 0.0168 * Sos_a_Grb2;
25: dGrb2/dt = -(0.025 * Sos_a * Grb2 - 0.0168 * Sos_a_Grb2) - (0.025 * Grb2 * Sos - 0.0168 * Sos_Grb2);
26: dSos_Grb2/dt = -(0.49998 * Sos_Grb2 * SHC_a - 0.1 * Shc_a_Sos_Grb2) + (0.025 * Grb2 * Sos - 0.0168 * Sos_Grb2);
27: dSos_a/dt = -(0.025 * Sos_a * Grb2 - 0.0168 * Sos_a_Grb2) - 0.001 * Sos_a;
28: dSos/dt = 0.001 * Sos_a - (0.025 * Grb2 * Sos - 0.0168 * Sos_Grb2);
29: dPKC_Ca/dt = 0.6 * PKC_cytosolic * 0.08 - 0.5 * PKC_Ca - (0.0079998 * 11.661 * PKC_Ca - 8.6348 * PKC_Ca_DAG) - (1.2705 * PKC_Ca - 3.5026 * PKC_Ca_memb_a) - (0.0012 * PKC_Ca * AA - 0.1 * PKC_Ca_AA_a);
30: dPKC_DAG_AA_a/dt = 2 * PKC_DAG_AA - 0.2 * PKC_DAG_AA_a;
31: dPKC_Ca_AA_a/dt = 0.0012 * PKC_Ca * AA - 0.1 * PKC_Ca_AA_a;
32: dPKC_Ca_memb_a/dt = 1.2705 * PKC_Ca - 3.5026 * PKC_Ca_memb_a;
33: dPKC_DAG_memb_a/dt = PKC_Ca_DAG - 0.1 * PKC_DAG_memb_a;
34: dPKC_basal_a/dt = PKC_cytosolic - 50 * PKC_basal_a;
35: dPKC_AA_a/dt = 0.00012 * AA * PKC_cytosolic - 0.1 * PKC_AA_a;
36: dPKC_Ca_DAG/dt = 0.0079998 * 11.661 * PKC_Ca - 8.6348 * PKC_Ca_DAG - (PKC_Ca_DAG - 0.1 * PKC_DAG_memb_a);
37: dPKC_DAG/dt = 0.0006 * PKC_cytosolic * 11.661 - 0.1 * PKC_DAG - (0.018 * PKC_DAG * AA - 2 * PKC_DAG_AA);
38: dPKC_DAG_AA/dt = -(2 * PKC_DAG_AA - 0.2 * PKC_DAG_AA_a) + (0.018 * PKC_DAG * AA - 2 * PKC_DAG_AA);
39: dPKC_cytosolic/dt = -(0.6 * PKC_cytosolic * 0.08 - 0.5 * PKC_Ca) - (PKC_cytosolic - 50 * PKC_basal_a) - (0.00012 * AA * PKC_cytosolic - 0.1 * PKC_AA_a) - (0.0006 * PKC_cytosolic * 11.661 - 0.1 * PKC_DAG);
40: dMAPK_MAPKK_a/dt = 16.2 * MAPK * MAPKK_a - 0.6 * MAPK_MAPKK_a - 0.15 * MAPK_MAPKK_a;
41: dMAPK_tyr_MAPKK_a/dt = 16.2 * MAPK_tyr * MAPKK_a - 0.6 * MAPK_tyr_MAPKK_a - 0.15 * MAPK_tyr_MAPKK_a;
42: dMAPKK_Raf_GTP_Ras_a/dt = 3.3 * MAPKK * Raf_GTP_Ras_a - 0.42 * MAPKK_Raf_GTP_Ras_a - 0.105 * MAPKK_Raf_GTP_Ras_a;
43: dMAPKK_ser_Raf_GTP_Ras_a/dt = 3.3 * MAPKK_ser * Raf_GTP_Ras_a - 0.42 * MAPKK_ser_Raf_GTP_Ras_a - 0.105 * MAPKK_ser_Raf_GTP_Ras_a;
44: dMAPKK_RGR/dt = 3.3 * MAPKK * RGR - 0.42 * MAPKK_RGR - 0.105 * MAPKK_RGR;
45: dMAPKK_ser_RGR/dt = 3.3 * MAPKK_ser * RGR - 0.42 * MAPKK_ser_RGR - 0.105 * MAPKK_ser_RGR;
46: dMAPK_tyr_MKP_1_a_a/dt = 74.999 * MAPK_tyr * MKP_1_a_a - 4 * MAPK_tyr_MKP_1_a_a - MAPK_tyr_MKP_1_a_a;
47: dMAPK_a_MKP_1_a_a/dt = 74.999 * MAPK_a * MKP_1_a_a - 4 * MAPK_a_MKP_1_a_a - MAPK_a_MKP_1_a_a;
48: dNucleotides_nuc_MAPK_a/dt = 0.001 * 0.1 * nuc_MAPK_a - 0.0032 * Nucleotides_nuc_MAPK_a - 0.0008 * Nucleotides_nuc_MAPK_a;
49: dcraf_1/dt = -(6 * craf_1 * GTP_Ras - RGR) - (0.3 * craf_1 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a) - 16 * craf_1_PKC_a_pool) + 6 * craf_1_a_PPhosphatase2A;
50: dcraf_1_a/dt = -(60 * craf_1_a * GTP_Ras - 0.5 * Raf_GTP_Ras_a) + 4 * craf_1_PKC_a_pool - (1.95 * craf_1_a * MAPK_a - 40 * craf_1_a_MAPK_a) - (1.98 * craf_1_a * PPhosphatase2A - 25.0002 * craf_1_a_PPhosphatase2A) + 6 * craf_1_a_a_PPhosphatase2A;
51: dMAPKK/dt = 6 * MAPKK_ser_PPhosphatase2A - (3.3 * MAPKK * Raf_GTP_Ras_a - 0.42 * MAPKK_Raf_GTP_Ras_a) - (3.3 * MAPKK * RGR - 0.42 * MAPKK_RGR);
52: dMAPK/dt = MAPK_tyr_MKP_1 + MAPK_tyr_MKP_2 - (16.2 * MAPK * MAPKK_a - 0.6 * MAPK_MAPKK_a) + MAPK_tyr_MKP_1_a_a;
53: dcraf_1_a_a/dt = 10 * craf_1_a_MAPK_a - (1.98 * craf_1_a_a * PPhosphatase2A - 25.0002 * craf_1_a_a_PPhosphatase2A);
54: dMAPK_tyr/dt = -(74.999 * MAPK_tyr * MKP_1 - 4 * MAPK_tyr_MKP_1) + MAPK_a_MKP_1 - (74.999 * MAPK_tyr * MKP_2 - 4 * MAPK_tyr_MKP_2) + MAPK_a_MKP_2 + 0.15 * MAPK_MAPKK_a - (16.2 * MAPK_tyr * MAPKK_a - 0.6 * MAPK_tyr_MAPKK_a) - (74.999 * MAPK_tyr * MKP_1_a_a - 4 * MAPK_tyr_MKP_1_a_a) + MAPK_a_MKP_1_a_a;
55: dMAPKK_a/dt = -(1.98 * MAPKK_a * PPhosphatase2A - 25.0002 * MAPKK_a_PPhosphatase2A) - (16.2 * MAPK * MAPKK_a - 0.6 * MAPK_MAPKK_a) + 0.15 * MAPK_MAPKK_a - (16.2 * MAPK_tyr * MAPKK_a - 0.6 * MAPK_tyr_MAPKK_a) + 0.15 * MAPK_tyr_MAPKK_a + 0.105 * MAPKK_ser_Raf_GTP_Ras_a + 0.105 * MAPKK_ser_RGR;
56: dMAPKK_ser/dt = 6 * MAPKK_a_PPhosphatase2A - (1.98 * MAPKK_ser * PPhosphatase2A - 25.0002 * MAPKK_ser_PPhosphatase2A) + 0.105 * MAPKK_Raf_GTP_Ras_a - (3.3 * MAPKK_ser * Raf_GTP_Ras_a - 0.42 * MAPKK_ser_Raf_GTP_Ras_a) + 0.105 * MAPKK_RGR - (3.3 * MAPKK_ser * RGR - 0.42 * MAPKK_ser_RGR);
57: dRaf_GTP_Ras_a/dt = 60 * craf_1_a * GTP_Ras - 0.5 * Raf_GTP_Ras_a - (3.3 * MAPKK * Raf_GTP_Ras_a - 0.42 * MAPKK_Raf_GTP_Ras_a) + 0.105 * MAPKK_Raf_GTP_Ras_a - (3.3 * MAPKK_ser * Raf_GTP_Ras_a - 0.42 * MAPKK_ser_Raf_GTP_Ras_a) + 0.105 * MAPKK_ser_Raf_GTP_Ras_a;
58: dRGR/dt = 6 * craf_1 * GTP_Ras - RGR - (3.3 * MAPKK * RGR - 0.42 * MAPKK_RGR) + 0.105 * MAPKK_RGR - (3.3 * MAPKK_ser * RGR - 0.42 * MAPKK_ser_RGR) + 0.105 * MAPKK_ser_RGR;
59: dUbiquitination/dt = 0.00037 * MKP_1 + 0.0001 * MKP_1_a_a + 0.0001 * MKP_1_ser359_a;
60: dMKP_1_ser359_a/dt = MKP_1_MAPK_a - (0.195 * MKP_1_ser359_a * MAPK_a - 4 * MKP_1_ser359_a_MAPK_a) - 0.0001 * MKP_1_ser359_a - 0.0001 * MKP_1_ser359_a + 0.0001 * MKP_1_a_a;
61: dMKP_1_a_a/dt = MKP_1_ser359_a_MAPK_a - 0.0001 * MKP_1_a_a - 0.0001 * MKP_1_a_a - (74.999 * MAPK_tyr * MKP_1_a_a - 4 * MAPK_tyr_MKP_1_a_a) + MAPK_tyr_MKP_1_a_a - (74.999 * MAPK_a * MKP_1_a_a - 4 * MAPK_a_MKP_1_a_a) + MAPK_a_MKP_1_a_a;
62: dnuc_MAPK_a/dt = 0.01 * pow(MAPK_a, 2) - 0.005 * nuc_MAPK_a - (0.001 * 0.1 * nuc_MAPK_a - 0.0032 * Nucleotides_nuc_MAPK_a) + 0.0008 * Nucleotides_nuc_MAPK_a;
63: dMKP1_RNA/dt = -(0.002 * MKP1_RNA) + 5e-06 * 0.1 + 0.0008 * Nucleotides_nuc_MAPK_a;
64: dAPC_PLA2_Ca_a/dt = 1.35 * 30 * PLA2_Ca_a - 21.6 * APC_PLA2_Ca_a - 5.4 * APC_PLA2_Ca_a;
65: dAPC_PIP2_PLA2_a/dt = 2.76 * 30 * PIP2_PLA2_a - 44.16 * APC_PIP2_PLA2_a - 11.04 * APC_PIP2_PLA2_a;
66: dAPC_PIP2_Ca_PLA2_a/dt = 9 * 30 * PIP2_Ca_PLA2_a - 144 * APC_PIP2_Ca_PLA2_a - 36 * APC_PIP2_Ca_PLA2_a;
67: dAPC_DAG_Ca_PLA2_a/dt = 15 * 30 * DAG_Ca_PLA2_a - 240 * APC_DAG_Ca_PLA2_a - 60 * APC_DAG_Ca_PLA2_a;
68: dAPC_PLA2_a_Ca/dt = 30 * 30 * PLA2_a_Ca - 480 * APC_PLA2_a_Ca - 120 * APC_PLA2_a_Ca;
69: dPLA2_cytosolic/dt = -(3.9 * PLA2_cytosolic * MAPK_a - 80 * PLA2_cytosolic_MAPK_a) - (PLA2_cytosolic * 0.08 - 0.1 * PLA2_Ca_a) - (0.0012 * 2.5 * PLA2_cytosolic - 0.5 * PIP2_PLA2_a) + 0.17 * PLA2_a;
70: dPLA2_Ca_a/dt = PLA2_cytosolic * 0.08 - 0.1 * PLA2_Ca_a - (0.012 * 2.5 * PLA2_Ca_a - 0.1 * PIP2_Ca_PLA2_a) - (0.003 * 11.661 * PLA2_Ca_a - 4 * DAG_Ca_PLA2_a) - (1.35 * 30 * PLA2_Ca_a - 21.6 * APC_PLA2_Ca_a) + 5.4 * APC_PLA2_Ca_a;
71: dPIP2_PLA2_a/dt = 0.0012 * 2.5 * PLA2_cytosolic - 0.5 * PIP2_PLA2_a - (2.76 * 30 * PIP2_PLA2_a - 44.16 * APC_PIP2_PLA2_a) + 11.04 * APC_PIP2_PLA2_a;
72: dPIP2_Ca_PLA2_a/dt = 0.012 * 2.5 * PLA2_Ca_a - 0.1 * PIP2_Ca_PLA2_a - (9 * 30 * PIP2_Ca_PLA2_a - 144 * APC_PIP2_Ca_PLA2_a) + 36 * APC_PIP2_Ca_PLA2_a;
73: dDAG_Ca_PLA2_a/dt = 0.003 * 11.661 * PLA2_Ca_a - 4 * DAG_Ca_PLA2_a - (15 * 30 * DAG_Ca_PLA2_a - 240 * APC_DAG_Ca_PLA2_a) + 60 * APC_DAG_Ca_PLA2_a;
74: dPLA2_a_Ca/dt = 6 * PLA2_a * 0.08 - 0.1 * PLA2_a_Ca - (30 * 30 * PLA2_a_Ca - 480 * APC_PLA2_a_Ca) + 120 * APC_PLA2_a_Ca;
75: dPLA2_a/dt = 20 * PLA2_cytosolic_MAPK_a - (6 * PLA2_a * 0.08 - 0.1 * PLA2_a_Ca) - 0.17 * PLA2_a;
76: dGDP_Ras_GEF_a/dt = 0.198 * GDP_Ras * GEF_a - 0.08 * GDP_Ras_GEF_a - 0.02 * GDP_Ras_GEF_a;
77: dGTP_Ras_GAP/dt = 999.6 * GTP_Ras * GAP - 1000 * GTP_Ras_GAP - 10 * GTP_Ras_GAP;
78: dinact_GEF/dt = -(0.3 * inact_GEF * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a) - 16 * inact_GEF_PKC_a_pool) + 0.1 * GEF_a;
79: dGEF_a/dt = 4 * inact_GEF_PKC_a_pool - 0.1 * GEF_a - (0.198 * GDP_Ras * GEF_a - 0.08 * GDP_Ras_GEF_a) + 0.02 * GDP_Ras_GEF_a;
80: dGTP_Ras/dt = -(60 * craf_1_a * GTP_Ras - 0.5 * Raf_GTP_Ras_a) - (6 * craf_1 * GTP_Ras - RGR) + 0.02 * GDP_Ras_Shc_a_Sos_Grb2 - 0.0001 * GTP_Ras + 0.02 * GDP_Ras_GEF_a - (999.6 * GTP_Ras * GAP - 1000 * GTP_Ras_GAP);
81: dGDP_Ras/dt = -(0.198 * GDP_Ras * Shc_a_Sos_Grb2 - 0.08 * GDP_Ras_Shc_a_Sos_Grb2) + 0.0001 * GTP_Ras - (0.198 * GDP_Ras * GEF_a - 0.08 * GDP_Ras_GEF_a) + 10 * GTP_Ras_GAP;
82: dGAP_a/dt = 25 * GAP_PKC_a_pool - 0.1 * GAP_a;
83: dGAP/dt = -(1.875 * GAP * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a) - 100 * GAP_PKC_a_pool) + 0.1 * GAP_a - (999.6 * GTP_Ras * GAP - 1000 * GTP_Ras_GAP) + 10 * GTP_Ras_GAP;
84: dSHC_L_PDGFR/dt = 0.3 * SHC * L_PDGFR - 0.2 * SHC_L_PDGFR - 0.05 * SHC_L_PDGFR;
85: dPDGFR/dt = -(200 * PDGFR * piecewise(geq(time, 300), 0, 0.0015) - 0.1 * L_PDGFR);
86: dL_PDGFR/dt = 200 * PDGFR * piecewise(geq(time, 300), 0, 0.0015) - 0.1 * L_PDGFR - (0.001 * L_PDGFR - 0.00066 * Internal_L_PDGFR) - (0.3 * SHC * L_PDGFR - 0.2 * SHC_L_PDGFR) + 0.05 * SHC_L_PDGFR;
87: dSHC/dt = 0.01 * SHC_a - (0.3 * SHC * L_PDGFR - 0.2 * SHC_L_PDGFR);
88: dSHC_a/dt = -(0.49998 * Sos_Grb2 * SHC_a - 0.1 * Shc_a_Sos_Grb2) - 0.01 * SHC_a + 0.05 * SHC_L_PDGFR;
89: dInternal_L_PDGFR/dt = 0.001 * L_PDGFR - 0.00066 * Internal_L_PDGFR;


# Jacobian Matrix:
# GDP_Ras_Shc_a_Sos_Grb2:
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = -0.08 - 0.02;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Shc_a_Sos_Grb2] = 0.198 * GDP_Ras;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[AA] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP_1] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PPhosphatase2A] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[tot_MKP1] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP_2] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Sos_a_Grb2] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Grb2] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Sos_Grb2] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Sos_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Sos] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_Ca] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_basal_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_AA_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_Ca_DAG] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_DAG] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_DAG_AA] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PKC_cytosolic] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_RGR] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[craf_1_a_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[RGR] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Ubiquitination] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP_1_ser359_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP_1_a_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[nuc_MAPK_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[MKP1_RNA] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PLA2_cytosolic] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PLA2_Ca_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PIP2_PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PLA2_a_Ca] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PLA2_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GTP_Ras_GAP] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[inact_GEF] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GEF_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GTP_Ras] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GDP_Ras] = 0.198 * Shc_a_Sos_Grb2;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GAP_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[GAP] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[SHC_L_PDGFR] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[PDGFR] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[L_PDGFR] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[SHC] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[SHC_a] = 0;
(d[GDP_Ras_Shc_a_Sos_Grb2]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1_PKC_a_pool:
(d[craf_1_PKC_a_pool]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[craf_1_PKC_a_pool] = -16 - 4;
(d[craf_1_PKC_a_pool]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[AA] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP_1] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PPhosphatase2A] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[tot_MKP1] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP_2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Grb2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Sos_Grb2] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Sos_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Sos] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_Ca] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_DAG_AA_a] = 0.3 * craf_1;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_Ca_AA_a] = 0.3 * craf_1;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_Ca_memb_a] = 0.3 * craf_1;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_DAG_memb_a] = 0.3 * craf_1;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_basal_a] = 0.3 * craf_1;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_AA_a] = 0.3 * craf_1;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_DAG] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[craf_1] = 0.3 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a);
(d[craf_1_PKC_a_pool]/dt)/d[craf_1_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[craf_1_a_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPK_tyr] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MAPKK_ser] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[RGR] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Ubiquitination] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[MKP1_RNA] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PLA2_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[inact_GEF] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GEF_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GTP_Ras] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GDP_Ras] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GAP_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[GAP] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[PDGFR] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[L_PDGFR] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[SHC] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[SHC_a] = 0;
(d[craf_1_PKC_a_pool]/dt)/d[Internal_L_PDGFR] = 0;
# GAP_PKC_a_pool:
(d[GAP_PKC_a_pool]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GAP_PKC_a_pool] = -100 - 25;
(d[GAP_PKC_a_pool]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[AA] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP_1] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PPhosphatase2A] = 0;
(d[GAP_PKC_a_pool]/dt)/d[tot_MKP1] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP_2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Sos_a_Grb2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Grb2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Sos_Grb2] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Sos_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Sos] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PKC_Ca] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PKC_DAG_AA_a] = 1.875 * GAP;
(d[GAP_PKC_a_pool]/dt)/d[PKC_Ca_AA_a] = 1.875 * GAP;
(d[GAP_PKC_a_pool]/dt)/d[PKC_Ca_memb_a] = 1.875 * GAP;
(d[GAP_PKC_a_pool]/dt)/d[PKC_DAG_memb_a] = 1.875 * GAP;
(d[GAP_PKC_a_pool]/dt)/d[PKC_basal_a] = 1.875 * GAP;
(d[GAP_PKC_a_pool]/dt)/d[PKC_AA_a] = 1.875 * GAP;
(d[GAP_PKC_a_pool]/dt)/d[PKC_Ca_DAG] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PKC_DAG] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PKC_DAG_AA] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PKC_cytosolic] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_RGR] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK] = 0;
(d[GAP_PKC_a_pool]/dt)/d[craf_1_a_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPK_tyr] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MAPKK_ser] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[RGR] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Ubiquitination] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP_1_ser359_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP_1_a_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[nuc_MAPK_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[MKP1_RNA] = 0;
(d[GAP_PKC_a_pool]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PLA2_cytosolic] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PLA2_Ca_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PIP2_PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PLA2_a_Ca] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PLA2_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GTP_Ras_GAP] = 0;
(d[GAP_PKC_a_pool]/dt)/d[inact_GEF] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GEF_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GTP_Ras] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GDP_Ras] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GAP_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[GAP] = 1.875 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a);
(d[GAP_PKC_a_pool]/dt)/d[SHC_L_PDGFR] = 0;
(d[GAP_PKC_a_pool]/dt)/d[PDGFR] = 0;
(d[GAP_PKC_a_pool]/dt)/d[L_PDGFR] = 0;
(d[GAP_PKC_a_pool]/dt)/d[SHC] = 0;
(d[GAP_PKC_a_pool]/dt)/d[SHC_a] = 0;
(d[GAP_PKC_a_pool]/dt)/d[Internal_L_PDGFR] = 0;
# inact_GEF_PKC_a_pool:
(d[inact_GEF_PKC_a_pool]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GAP_PKC_a_pool] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[inact_GEF_PKC_a_pool] = -16 - 4;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP_1_MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_a_MKP_1] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_a_MKP_2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[AA] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP_1] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PPhosphatase2A] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[tot_MKP1] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP_2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Sos_a_Grb2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Grb2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Sos_Grb2] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Sos_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Sos] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_Ca] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_DAG_AA_a] = 0.3 * inact_GEF;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_Ca_AA_a] = 0.3 * inact_GEF;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_Ca_memb_a] = 0.3 * inact_GEF;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_DAG_memb_a] = 0.3 * inact_GEF;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_basal_a] = 0.3 * inact_GEF;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_AA_a] = 0.3 * inact_GEF;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_Ca_DAG] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_DAG] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_DAG_AA] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PKC_cytosolic] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_MAPKK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_RGR] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_ser_RGR] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[craf_1_a_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPK_tyr] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MAPKK_ser] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[RGR] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Ubiquitination] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP_1_ser359_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP_1_a_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[nuc_MAPK_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[MKP1_RNA] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PLA2_cytosolic] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PLA2_Ca_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PIP2_PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PLA2_a_Ca] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PLA2_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GTP_Ras_GAP] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[inact_GEF] = 0.3 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a);
(d[inact_GEF_PKC_a_pool]/dt)/d[GEF_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GTP_Ras] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GDP_Ras] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GAP_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[GAP] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[SHC_L_PDGFR] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[PDGFR] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[L_PDGFR] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[SHC] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[SHC_a] = 0;
(d[inact_GEF_PKC_a_pool]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1_a_MAPK_a:
(d[craf_1_a_MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1_a_MAPK_a] = -40 - 10;
(d[craf_1_a_MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[AA] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_a] = 1.95 * craf_1_a;
(d[craf_1_a_MAPK_a]/dt)/d[MKP_1] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MKP_2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Grb2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Sos_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Sos] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1_a] = 1.95 * MAPK_a;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[RGR] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PLA2_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[inact_GEF] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GEF_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GAP_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[GAP] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[PDGFR] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[SHC] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[SHC_a] = 0;
(d[craf_1_a_MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# PLA2_cytosolic_MAPK_a:
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = -80 - 20;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[AA] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_a] = 3.9 * PLA2_cytosolic;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP_1] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP_2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Grb2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Sos_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Sos] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[RGR] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP_1_a_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PLA2_cytosolic] = 3.9 * MAPK_a;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PLA2_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[inact_GEF] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GEF_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GAP_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[GAP] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[PDGFR] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[SHC] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[SHC_a] = 0;
(d[PLA2_cytosolic_MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MKP_1_MAPK_a:
(d[MKP_1_MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP_1_MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MKP_1_MAPK_a] = -4 - 1;
(d[MKP_1_MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[AA] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_a] = 0.195 * MKP_1;
(d[MKP_1_MAPK_a]/dt)/d[MKP_1] = 0.195 * MAPK_a;
(d[MKP_1_MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[MKP_1_MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MKP_2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Grb2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Sos_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Sos] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK] = 0;
(d[MKP_1_MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[RGR] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MKP_1_a_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[MKP_1_MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PLA2_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP_1_MAPK_a]/dt)/d[inact_GEF] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GEF_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GAP_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[GAP] = 0;
(d[MKP_1_MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP_1_MAPK_a]/dt)/d[PDGFR] = 0;
(d[MKP_1_MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[MKP_1_MAPK_a]/dt)/d[SHC] = 0;
(d[MKP_1_MAPK_a]/dt)/d[SHC_a] = 0;
(d[MKP_1_MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MKP_1_ser359_a_MAPK_a:
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = -4 - 1;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[AA] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_a] = 0.195 * MKP_1_ser359_a;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP_1] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP_2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Grb2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Sos_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Sos] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[RGR] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP_1_ser359_a] = 0.195 * MAPK_a;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP_1_a_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PLA2_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[inact_GEF] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GEF_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GAP_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[GAP] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[PDGFR] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[SHC] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[SHC_a] = 0;
(d[MKP_1_ser359_a_MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_tyr_MKP_1:
(d[MAPK_tyr_MKP_1]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_tyr_MKP_1] = -4 - 1;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[AA] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP_1] = 74.999 * MAPK_tyr;
(d[MAPK_tyr_MKP_1]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[tot_MKP1] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP_2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Grb2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Sos_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Sos] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_Ca] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_DAG] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPK_tyr] = 74.999 * MKP_1;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[RGR] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Ubiquitination] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PLA2_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[inact_GEF] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GEF_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GTP_Ras] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GDP_Ras] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GAP_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[GAP] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[PDGFR] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[L_PDGFR] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[SHC] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[SHC_a] = 0;
(d[MAPK_tyr_MKP_1]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_a_MKP_1:
(d[MAPK_a_MKP_1]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_a_MKP_1]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_a_MKP_1]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_a_MKP_1] = -4 - 1;
(d[MAPK_a_MKP_1]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[AA] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_a] = 74.999 * MKP_1;
(d[MAPK_a_MKP_1]/dt)/d[MKP_1] = 74.999 * MAPK_a;
(d[MAPK_a_MKP_1]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1]/dt)/d[tot_MKP1] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MKP_2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Grb2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Sos_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Sos] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_Ca] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_DAG] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[craf_1] = 0;
(d[MAPK_a_MKP_1]/dt)/d[craf_1_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK] = 0;
(d[MAPK_a_MKP_1]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPK_tyr] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[RGR] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Ubiquitination] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_a_MKP_1]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PLA2_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_a_MKP_1]/dt)/d[inact_GEF] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GEF_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GTP_Ras] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GDP_Ras] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GAP_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[GAP] = 0;
(d[MAPK_a_MKP_1]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_a_MKP_1]/dt)/d[PDGFR] = 0;
(d[MAPK_a_MKP_1]/dt)/d[L_PDGFR] = 0;
(d[MAPK_a_MKP_1]/dt)/d[SHC] = 0;
(d[MAPK_a_MKP_1]/dt)/d[SHC_a] = 0;
(d[MAPK_a_MKP_1]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1_a_PPhosphatase2A:
(d[craf_1_a_PPhosphatase2A]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1_a_PPhosphatase2A] = -25.0002 - 6;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[AA] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP_1] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PPhosphatase2A] = 1.98 * craf_1_a;
(d[craf_1_a_PPhosphatase2A]/dt)/d[tot_MKP1] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP_2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Grb2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Sos_Grb2] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Sos_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Sos] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_Ca] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_DAG_AA_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_Ca_AA_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_Ca_memb_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_DAG_memb_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_basal_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_AA_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_DAG] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1_a] = 1.98 * PPhosphatase2A;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[craf_1_a_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPK_tyr] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MAPKK_ser] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[RGR] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Ubiquitination] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[MKP1_RNA] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PLA2_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[inact_GEF] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GEF_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GTP_Ras] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GDP_Ras] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GAP_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[GAP] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[PDGFR] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[L_PDGFR] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[SHC] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[SHC_a] = 0;
(d[craf_1_a_PPhosphatase2A]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_a_PPhosphatase2A:
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_a_PPhosphatase2A] = -25.0002 - 6;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[AA] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP_1] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PPhosphatase2A] = 1.98 * MAPKK_a;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP_2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Grb2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Sos_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Sos] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_RGR] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_a] = 1.98 * PPhosphatase2A;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MAPKK_ser] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[RGR] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PLA2_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[inact_GEF] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GEF_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GAP_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[GAP] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[PDGFR] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[SHC] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[SHC_a] = 0;
(d[MAPKK_a_PPhosphatase2A]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_ser_PPhosphatase2A:
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_ser_PPhosphatase2A] = -25.0002 - 6;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[AA] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP_1] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PPhosphatase2A] = 1.98 * MAPKK_ser;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP_2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Grb2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Sos_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Sos] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_RGR] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MAPKK_ser] = 1.98 * PPhosphatase2A;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[RGR] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PLA2_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[inact_GEF] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GEF_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GAP_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[GAP] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[PDGFR] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[SHC] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[SHC_a] = 0;
(d[MAPKK_ser_PPhosphatase2A]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1_a_a_PPhosphatase2A:
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1_a_a_PPhosphatase2A] = -25.0002 - 6;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[AA] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP_1] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PPhosphatase2A] = 1.98 * craf_1_a_a;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[tot_MKP1] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP_2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Grb2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Sos_Grb2] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Sos_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Sos] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_Ca] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_DAG_AA_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_Ca_AA_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_Ca_memb_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_DAG_memb_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_basal_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_AA_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_DAG] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[craf_1_a_a] = 1.98 * PPhosphatase2A;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPK_tyr] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MAPKK_ser] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[RGR] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Ubiquitination] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[MKP1_RNA] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PLA2_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[inact_GEF] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GEF_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GTP_Ras] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GDP_Ras] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GAP_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[GAP] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[PDGFR] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[L_PDGFR] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[SHC] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[SHC_a] = 0;
(d[craf_1_a_a_PPhosphatase2A]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_tyr_MKP_2:
(d[MAPK_tyr_MKP_2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_tyr_MKP_2] = -4 - 1;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[AA] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP_1] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[tot_MKP1] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP_2] = 74.999 * MAPK_tyr;
(d[MAPK_tyr_MKP_2]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Grb2] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Sos_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Sos] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_Ca] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_DAG] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPK_tyr] = 74.999 * MKP_2;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[RGR] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Ubiquitination] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PLA2_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[inact_GEF] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GEF_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GTP_Ras] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GDP_Ras] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GAP_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[GAP] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[PDGFR] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[L_PDGFR] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[SHC] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[SHC_a] = 0;
(d[MAPK_tyr_MKP_2]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_a_MKP_2:
(d[MAPK_a_MKP_2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_a_MKP_2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_a_MKP_2] = -4 - 1;
(d[MAPK_a_MKP_2]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_a_MKP_2]/dt)/d[AA] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_a] = 74.999 * MKP_2;
(d[MAPK_a_MKP_2]/dt)/d[MKP_1] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_a_MKP_2]/dt)/d[tot_MKP1] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MKP_2] = 74.999 * MAPK_a;
(d[MAPK_a_MKP_2]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Grb2] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Sos_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Sos] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_Ca] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_DAG] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK] = 0;
(d[MAPK_a_MKP_2]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPK_tyr] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[RGR] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Ubiquitination] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_a_MKP_2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PLA2_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_a_MKP_2]/dt)/d[inact_GEF] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GEF_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GTP_Ras] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GDP_Ras] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GAP_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[GAP] = 0;
(d[MAPK_a_MKP_2]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_a_MKP_2]/dt)/d[PDGFR] = 0;
(d[MAPK_a_MKP_2]/dt)/d[L_PDGFR] = 0;
(d[MAPK_a_MKP_2]/dt)/d[SHC] = 0;
(d[MAPK_a_MKP_2]/dt)/d[SHC_a] = 0;
(d[MAPK_a_MKP_2]/dt)/d[Internal_L_PDGFR] = 0;
# Shc_a_Sos_Grb2:
(d[Shc_a_Sos_Grb2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0.08 + 0.02;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Shc_a_Sos_Grb2] = -(0.198 * GDP_Ras) + -0.1;
(d[Shc_a_Sos_Grb2]/dt)/d[AA] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP_1] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PPhosphatase2A] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[tot_MKP1] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP_2] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Sos_a_Grb2] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Grb2] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Sos_Grb2] = 0.49998 * SHC_a;
(d[Shc_a_Sos_Grb2]/dt)/d[Sos_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Sos] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_Ca] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_basal_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_AA_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_Ca_DAG] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_DAG] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_DAG_AA] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PKC_cytosolic] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_RGR] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[craf_1_a_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPK_tyr] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MAPKK_ser] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[RGR] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[Ubiquitination] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP_1_ser359_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP_1_a_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[nuc_MAPK_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[MKP1_RNA] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PLA2_cytosolic] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PLA2_Ca_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PIP2_PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PLA2_a_Ca] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PLA2_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GTP_Ras_GAP] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[inact_GEF] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GEF_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GTP_Ras] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GDP_Ras] = -(0.198 * Shc_a_Sos_Grb2);
(d[Shc_a_Sos_Grb2]/dt)/d[GAP_a] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[GAP] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[SHC_L_PDGFR] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[PDGFR] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[L_PDGFR] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[SHC] = 0;
(d[Shc_a_Sos_Grb2]/dt)/d[SHC_a] = 0.49998 * Sos_Grb2;
(d[Shc_a_Sos_Grb2]/dt)/d[Internal_L_PDGFR] = 0;
# AA:
(d[AA]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[AA]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[AA]/dt)/d[GAP_PKC_a_pool] = 0;
(d[AA]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[AA]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[AA]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[AA]/dt)/d[MKP_1_MAPK_a] = 0;
(d[AA]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[AA]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[AA]/dt)/d[MAPK_a_MKP_1] = 0;
(d[AA]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[AA]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[AA]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[AA]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[AA]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[AA]/dt)/d[MAPK_a_MKP_2] = 0;
(d[AA]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[AA]/dt)/d[AA] = -(0.0012 * PKC_Ca) - 0.00012 * PKC_cytosolic - 0.018 * PKC_DAG - 0.4;
(d[AA]/dt)/d[MAPK_a] = 0;
(d[AA]/dt)/d[MKP_1] = 0;
(d[AA]/dt)/d[PPhosphatase2A] = 0;
(d[AA]/dt)/d[tot_MKP1] = 0;
(d[AA]/dt)/d[MKP_2] = 0;
(d[AA]/dt)/d[Sos_a_Grb2] = 0;
(d[AA]/dt)/d[Grb2] = 0;
(d[AA]/dt)/d[Sos_Grb2] = 0;
(d[AA]/dt)/d[Sos_a] = 0;
(d[AA]/dt)/d[Sos] = 0;
(d[AA]/dt)/d[PKC_Ca] = -(0.0012 * AA);
(d[AA]/dt)/d[PKC_DAG_AA_a] = 0;
(d[AA]/dt)/d[PKC_Ca_AA_a] = 0.1;
(d[AA]/dt)/d[PKC_Ca_memb_a] = 0;
(d[AA]/dt)/d[PKC_DAG_memb_a] = 0;
(d[AA]/dt)/d[PKC_basal_a] = 0;
(d[AA]/dt)/d[PKC_AA_a] = --0.1;
(d[AA]/dt)/d[PKC_Ca_DAG] = 0;
(d[AA]/dt)/d[PKC_DAG] = -(0.018 * AA);
(d[AA]/dt)/d[PKC_DAG_AA] = --2;
(d[AA]/dt)/d[PKC_cytosolic] = -(0.00012 * AA);
(d[AA]/dt)/d[MAPK_MAPKK_a] = 0;
(d[AA]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[AA]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[AA]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[AA]/dt)/d[MAPKK_RGR] = 0;
(d[AA]/dt)/d[MAPKK_ser_RGR] = 0;
(d[AA]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[AA]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[AA]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[AA]/dt)/d[craf_1] = 0;
(d[AA]/dt)/d[craf_1_a] = 0;
(d[AA]/dt)/d[MAPKK] = 0;
(d[AA]/dt)/d[MAPK] = 0;
(d[AA]/dt)/d[craf_1_a_a] = 0;
(d[AA]/dt)/d[MAPK_tyr] = 0;
(d[AA]/dt)/d[MAPKK_a] = 0;
(d[AA]/dt)/d[MAPKK_ser] = 0;
(d[AA]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[AA]/dt)/d[RGR] = 0;
(d[AA]/dt)/d[Ubiquitination] = 0;
(d[AA]/dt)/d[MKP_1_ser359_a] = 0;
(d[AA]/dt)/d[MKP_1_a_a] = 0;
(d[AA]/dt)/d[nuc_MAPK_a] = 0;
(d[AA]/dt)/d[MKP1_RNA] = 0;
(d[AA]/dt)/d[APC_PLA2_Ca_a] = 5.4;
(d[AA]/dt)/d[APC_PIP2_PLA2_a] = 11.04;
(d[AA]/dt)/d[APC_PIP2_Ca_PLA2_a] = 36;
(d[AA]/dt)/d[APC_DAG_Ca_PLA2_a] = 60;
(d[AA]/dt)/d[APC_PLA2_a_Ca] = 120;
(d[AA]/dt)/d[PLA2_cytosolic] = 0;
(d[AA]/dt)/d[PLA2_Ca_a] = 0;
(d[AA]/dt)/d[PIP2_PLA2_a] = 0;
(d[AA]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[AA]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[AA]/dt)/d[PLA2_a_Ca] = 0;
(d[AA]/dt)/d[PLA2_a] = 0;
(d[AA]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[AA]/dt)/d[GTP_Ras_GAP] = 0;
(d[AA]/dt)/d[inact_GEF] = 0;
(d[AA]/dt)/d[GEF_a] = 0;
(d[AA]/dt)/d[GTP_Ras] = 0;
(d[AA]/dt)/d[GDP_Ras] = 0;
(d[AA]/dt)/d[GAP_a] = 0;
(d[AA]/dt)/d[GAP] = 0;
(d[AA]/dt)/d[SHC_L_PDGFR] = 0;
(d[AA]/dt)/d[PDGFR] = 0;
(d[AA]/dt)/d[L_PDGFR] = 0;
(d[AA]/dt)/d[SHC] = 0;
(d[AA]/dt)/d[SHC_a] = 0;
(d[AA]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_a:
(d[MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_a]/dt)/d[craf_1_a_MAPK_a] = 40 + 10;
(d[MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = --80 + 20;
(d[MAPK_a]/dt)/d[MKP_1_MAPK_a] = --4 + 1;
(d[MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = --4 + 1;
(d[MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_a]/dt)/d[MAPK_a_MKP_1] = --4;
(d[MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_a]/dt)/d[MAPK_a_MKP_2] = --4;
(d[MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_a]/dt)/d[AA] = 0;
(d[MAPK_a]/dt)/d[MAPK_a] = -(1.95 * craf_1_a) - 3.9 * PLA2_cytosolic - 0.195 * MKP_1 - 0.195 * MKP_1_ser359_a - 74.999 * MKP_1 - 74.999 * MKP_2 - 2 * 0.01 * 2 * MAPK_a - 74.999 * MKP_1_a_a;
(d[MAPK_a]/dt)/d[MKP_1] = -(0.195 * MAPK_a) - 74.999 * MAPK_a;
(d[MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[MAPK_a]/dt)/d[MKP_2] = -(74.999 * MAPK_a);
(d[MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_a]/dt)/d[Grb2] = 0;
(d[MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_a]/dt)/d[Sos_a] = 0;
(d[MAPK_a]/dt)/d[Sos] = 0;
(d[MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0.15;
(d[MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = --4;
(d[MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_a]/dt)/d[craf_1] = 0;
(d[MAPK_a]/dt)/d[craf_1_a] = -(1.95 * MAPK_a);
(d[MAPK_a]/dt)/d[MAPKK] = 0;
(d[MAPK_a]/dt)/d[MAPK] = 0;
(d[MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_a]/dt)/d[RGR] = 0;
(d[MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[MAPK_a]/dt)/d[MKP_1_ser359_a] = -(0.195 * MAPK_a);
(d[MAPK_a]/dt)/d[MKP_1_a_a] = -(74.999 * MAPK_a);
(d[MAPK_a]/dt)/d[nuc_MAPK_a] = --0.01;
(d[MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_a]/dt)/d[PLA2_cytosolic] = -(3.9 * MAPK_a);
(d[MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_a]/dt)/d[PLA2_a] = 0;
(d[MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_a]/dt)/d[inact_GEF] = 0;
(d[MAPK_a]/dt)/d[GEF_a] = 0;
(d[MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[MAPK_a]/dt)/d[GAP_a] = 0;
(d[MAPK_a]/dt)/d[GAP] = 0;
(d[MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_a]/dt)/d[PDGFR] = 0;
(d[MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[MAPK_a]/dt)/d[SHC] = 0;
(d[MAPK_a]/dt)/d[SHC_a] = 0;
(d[MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MKP_1:
(d[MKP_1]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP_1]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP_1]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP_1]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP_1]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP_1]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP_1]/dt)/d[MKP_1_MAPK_a] = 4;
(d[MKP_1]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MKP_1]/dt)/d[MAPK_tyr_MKP_1] = --4 + 1;
(d[MKP_1]/dt)/d[MAPK_a_MKP_1] = --4 + 1;
(d[MKP_1]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP_1]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP_1]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP_1]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP_1]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MKP_1]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MKP_1]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP_1]/dt)/d[AA] = 0;
(d[MKP_1]/dt)/d[MAPK_a] = -(0.195 * MKP_1) - 74.999 * MKP_1;
(d[MKP_1]/dt)/d[MKP_1] = -(0.195 * MAPK_a) - 74.999 * MAPK_tyr - 74.999 * MAPK_a - 0.00037;
(d[MKP_1]/dt)/d[PPhosphatase2A] = 0;
(d[MKP_1]/dt)/d[tot_MKP1] = 0;
(d[MKP_1]/dt)/d[MKP_2] = 0;
(d[MKP_1]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP_1]/dt)/d[Grb2] = 0;
(d[MKP_1]/dt)/d[Sos_Grb2] = 0;
(d[MKP_1]/dt)/d[Sos_a] = 0;
(d[MKP_1]/dt)/d[Sos] = 0;
(d[MKP_1]/dt)/d[PKC_Ca] = 0;
(d[MKP_1]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP_1]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP_1]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP_1]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP_1]/dt)/d[PKC_basal_a] = 0;
(d[MKP_1]/dt)/d[PKC_AA_a] = 0;
(d[MKP_1]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP_1]/dt)/d[PKC_DAG] = 0;
(d[MKP_1]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP_1]/dt)/d[PKC_cytosolic] = 0;
(d[MKP_1]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP_1]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP_1]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP_1]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP_1]/dt)/d[MAPKK_RGR] = 0;
(d[MKP_1]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP_1]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MKP_1]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MKP_1]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MKP_1]/dt)/d[craf_1] = 0;
(d[MKP_1]/dt)/d[craf_1_a] = 0;
(d[MKP_1]/dt)/d[MAPKK] = 0;
(d[MKP_1]/dt)/d[MAPK] = 0;
(d[MKP_1]/dt)/d[craf_1_a_a] = 0;
(d[MKP_1]/dt)/d[MAPK_tyr] = -(74.999 * MKP_1);
(d[MKP_1]/dt)/d[MAPKK_a] = 0;
(d[MKP_1]/dt)/d[MAPKK_ser] = 0;
(d[MKP_1]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP_1]/dt)/d[RGR] = 0;
(d[MKP_1]/dt)/d[Ubiquitination] = 0;
(d[MKP_1]/dt)/d[MKP_1_ser359_a] = 0.0001;
(d[MKP_1]/dt)/d[MKP_1_a_a] = 0;
(d[MKP_1]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP_1]/dt)/d[MKP1_RNA] = 0.002;
(d[MKP_1]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP_1]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP_1]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP_1]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP_1]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP_1]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP_1]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP_1]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP_1]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP_1]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP_1]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP_1]/dt)/d[PLA2_a] = 0;
(d[MKP_1]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP_1]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP_1]/dt)/d[inact_GEF] = 0;
(d[MKP_1]/dt)/d[GEF_a] = 0;
(d[MKP_1]/dt)/d[GTP_Ras] = 0;
(d[MKP_1]/dt)/d[GDP_Ras] = 0;
(d[MKP_1]/dt)/d[GAP_a] = 0;
(d[MKP_1]/dt)/d[GAP] = 0;
(d[MKP_1]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP_1]/dt)/d[PDGFR] = 0;
(d[MKP_1]/dt)/d[L_PDGFR] = 0;
(d[MKP_1]/dt)/d[SHC] = 0;
(d[MKP_1]/dt)/d[SHC_a] = 0;
(d[MKP_1]/dt)/d[Internal_L_PDGFR] = 0;
# PPhosphatase2A:
(d[PPhosphatase2A]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PPhosphatase2A]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PPhosphatase2A]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PPhosphatase2A]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PPhosphatase2A]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PPhosphatase2A]/dt)/d[craf_1_a_PPhosphatase2A] = 25.0002 + 6;
(d[PPhosphatase2A]/dt)/d[MAPKK_a_PPhosphatase2A] = --25.0002 + 6;
(d[PPhosphatase2A]/dt)/d[MAPKK_ser_PPhosphatase2A] = --25.0002 + 6;
(d[PPhosphatase2A]/dt)/d[craf_1_a_a_PPhosphatase2A] = --25.0002 + 6;
(d[PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PPhosphatase2A]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PPhosphatase2A]/dt)/d[AA] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MKP_1] = 0;
(d[PPhosphatase2A]/dt)/d[PPhosphatase2A] = -(1.98 * craf_1_a) - 1.98 * MAPKK_a - 1.98 * MAPKK_ser - 1.98 * craf_1_a_a;
(d[PPhosphatase2A]/dt)/d[tot_MKP1] = 0;
(d[PPhosphatase2A]/dt)/d[MKP_2] = 0;
(d[PPhosphatase2A]/dt)/d[Sos_a_Grb2] = 0;
(d[PPhosphatase2A]/dt)/d[Grb2] = 0;
(d[PPhosphatase2A]/dt)/d[Sos_Grb2] = 0;
(d[PPhosphatase2A]/dt)/d[Sos_a] = 0;
(d[PPhosphatase2A]/dt)/d[Sos] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_Ca] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_basal_a] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_AA_a] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_Ca_DAG] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_DAG] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_DAG_AA] = 0;
(d[PPhosphatase2A]/dt)/d[PKC_cytosolic] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PPhosphatase2A]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PPhosphatase2A]/dt)/d[MAPKK_RGR] = 0;
(d[PPhosphatase2A]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PPhosphatase2A]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[craf_1] = 0;
(d[PPhosphatase2A]/dt)/d[craf_1_a] = -(1.98 * PPhosphatase2A);
(d[PPhosphatase2A]/dt)/d[MAPKK] = 0;
(d[PPhosphatase2A]/dt)/d[MAPK] = 0;
(d[PPhosphatase2A]/dt)/d[craf_1_a_a] = -(1.98 * PPhosphatase2A);
(d[PPhosphatase2A]/dt)/d[MAPK_tyr] = 0;
(d[PPhosphatase2A]/dt)/d[MAPKK_a] = -(1.98 * PPhosphatase2A);
(d[PPhosphatase2A]/dt)/d[MAPKK_ser] = -(1.98 * PPhosphatase2A);
(d[PPhosphatase2A]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PPhosphatase2A]/dt)/d[RGR] = 0;
(d[PPhosphatase2A]/dt)/d[Ubiquitination] = 0;
(d[PPhosphatase2A]/dt)/d[MKP_1_ser359_a] = 0;
(d[PPhosphatase2A]/dt)/d[MKP_1_a_a] = 0;
(d[PPhosphatase2A]/dt)/d[nuc_MAPK_a] = 0;
(d[PPhosphatase2A]/dt)/d[MKP1_RNA] = 0;
(d[PPhosphatase2A]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PPhosphatase2A]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PPhosphatase2A]/dt)/d[PLA2_cytosolic] = 0;
(d[PPhosphatase2A]/dt)/d[PLA2_Ca_a] = 0;
(d[PPhosphatase2A]/dt)/d[PIP2_PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[PLA2_a_Ca] = 0;
(d[PPhosphatase2A]/dt)/d[PLA2_a] = 0;
(d[PPhosphatase2A]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PPhosphatase2A]/dt)/d[GTP_Ras_GAP] = 0;
(d[PPhosphatase2A]/dt)/d[inact_GEF] = 0;
(d[PPhosphatase2A]/dt)/d[GEF_a] = 0;
(d[PPhosphatase2A]/dt)/d[GTP_Ras] = 0;
(d[PPhosphatase2A]/dt)/d[GDP_Ras] = 0;
(d[PPhosphatase2A]/dt)/d[GAP_a] = 0;
(d[PPhosphatase2A]/dt)/d[GAP] = 0;
(d[PPhosphatase2A]/dt)/d[SHC_L_PDGFR] = 0;
(d[PPhosphatase2A]/dt)/d[PDGFR] = 0;
(d[PPhosphatase2A]/dt)/d[L_PDGFR] = 0;
(d[PPhosphatase2A]/dt)/d[SHC] = 0;
(d[PPhosphatase2A]/dt)/d[SHC_a] = 0;
(d[PPhosphatase2A]/dt)/d[Internal_L_PDGFR] = 0;
# tot_MKP1:
(d[tot_MKP1]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[tot_MKP1]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[tot_MKP1]/dt)/d[GAP_PKC_a_pool] = 0;
(d[tot_MKP1]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[tot_MKP1]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[MKP_1_MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[tot_MKP1]/dt)/d[MAPK_a_MKP_1] = 0;
(d[tot_MKP1]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[tot_MKP1]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[tot_MKP1]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[tot_MKP1]/dt)/d[MAPK_a_MKP_2] = 0;
(d[tot_MKP1]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[tot_MKP1]/dt)/d[AA] = 0;
(d[tot_MKP1]/dt)/d[MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[MKP_1] = 0;
(d[tot_MKP1]/dt)/d[PPhosphatase2A] = 0;
(d[tot_MKP1]/dt)/d[tot_MKP1] = 0;
(d[tot_MKP1]/dt)/d[MKP_2] = 0;
(d[tot_MKP1]/dt)/d[Sos_a_Grb2] = 0;
(d[tot_MKP1]/dt)/d[Grb2] = 0;
(d[tot_MKP1]/dt)/d[Sos_Grb2] = 0;
(d[tot_MKP1]/dt)/d[Sos_a] = 0;
(d[tot_MKP1]/dt)/d[Sos] = 0;
(d[tot_MKP1]/dt)/d[PKC_Ca] = 0;
(d[tot_MKP1]/dt)/d[PKC_DAG_AA_a] = 0;
(d[tot_MKP1]/dt)/d[PKC_Ca_AA_a] = 0;
(d[tot_MKP1]/dt)/d[PKC_Ca_memb_a] = 0;
(d[tot_MKP1]/dt)/d[PKC_DAG_memb_a] = 0;
(d[tot_MKP1]/dt)/d[PKC_basal_a] = 0;
(d[tot_MKP1]/dt)/d[PKC_AA_a] = 0;
(d[tot_MKP1]/dt)/d[PKC_Ca_DAG] = 0;
(d[tot_MKP1]/dt)/d[PKC_DAG] = 0;
(d[tot_MKP1]/dt)/d[PKC_DAG_AA] = 0;
(d[tot_MKP1]/dt)/d[PKC_cytosolic] = 0;
(d[tot_MKP1]/dt)/d[MAPK_MAPKK_a] = 0;
(d[tot_MKP1]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_RGR] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_ser_RGR] = 0;
(d[tot_MKP1]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[tot_MKP1]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[tot_MKP1]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[craf_1] = 0;
(d[tot_MKP1]/dt)/d[craf_1_a] = 0;
(d[tot_MKP1]/dt)/d[MAPKK] = 0;
(d[tot_MKP1]/dt)/d[MAPK] = 0;
(d[tot_MKP1]/dt)/d[craf_1_a_a] = 0;
(d[tot_MKP1]/dt)/d[MAPK_tyr] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_a] = 0;
(d[tot_MKP1]/dt)/d[MAPKK_ser] = 0;
(d[tot_MKP1]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[tot_MKP1]/dt)/d[RGR] = 0;
(d[tot_MKP1]/dt)/d[Ubiquitination] = 0;
(d[tot_MKP1]/dt)/d[MKP_1_ser359_a] = 0;
(d[tot_MKP1]/dt)/d[MKP_1_a_a] = 0;
(d[tot_MKP1]/dt)/d[nuc_MAPK_a] = 0;
(d[tot_MKP1]/dt)/d[MKP1_RNA] = 0;
(d[tot_MKP1]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[tot_MKP1]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[tot_MKP1]/dt)/d[PLA2_cytosolic] = 0;
(d[tot_MKP1]/dt)/d[PLA2_Ca_a] = 0;
(d[tot_MKP1]/dt)/d[PIP2_PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[PLA2_a_Ca] = 0;
(d[tot_MKP1]/dt)/d[PLA2_a] = 0;
(d[tot_MKP1]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[tot_MKP1]/dt)/d[GTP_Ras_GAP] = 0;
(d[tot_MKP1]/dt)/d[inact_GEF] = 0;
(d[tot_MKP1]/dt)/d[GEF_a] = 0;
(d[tot_MKP1]/dt)/d[GTP_Ras] = 0;
(d[tot_MKP1]/dt)/d[GDP_Ras] = 0;
(d[tot_MKP1]/dt)/d[GAP_a] = 0;
(d[tot_MKP1]/dt)/d[GAP] = 0;
(d[tot_MKP1]/dt)/d[SHC_L_PDGFR] = 0;
(d[tot_MKP1]/dt)/d[PDGFR] = 0;
(d[tot_MKP1]/dt)/d[L_PDGFR] = 0;
(d[tot_MKP1]/dt)/d[SHC] = 0;
(d[tot_MKP1]/dt)/d[SHC_a] = 0;
(d[tot_MKP1]/dt)/d[Internal_L_PDGFR] = 0;
# MKP_2:
(d[MKP_2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP_2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP_2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP_2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP_2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP_2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP_2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MKP_2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MKP_2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MKP_2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MKP_2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP_2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP_2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP_2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP_2]/dt)/d[MAPK_tyr_MKP_2] = 4 + 1;
(d[MKP_2]/dt)/d[MAPK_a_MKP_2] = --4 + 1;
(d[MKP_2]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP_2]/dt)/d[AA] = 0;
(d[MKP_2]/dt)/d[MAPK_a] = -(74.999 * MKP_2);
(d[MKP_2]/dt)/d[MKP_1] = 0;
(d[MKP_2]/dt)/d[PPhosphatase2A] = 0;
(d[MKP_2]/dt)/d[tot_MKP1] = 0;
(d[MKP_2]/dt)/d[MKP_2] = -(74.999 * MAPK_tyr) - 74.999 * MAPK_a;
(d[MKP_2]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP_2]/dt)/d[Grb2] = 0;
(d[MKP_2]/dt)/d[Sos_Grb2] = 0;
(d[MKP_2]/dt)/d[Sos_a] = 0;
(d[MKP_2]/dt)/d[Sos] = 0;
(d[MKP_2]/dt)/d[PKC_Ca] = 0;
(d[MKP_2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP_2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP_2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP_2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP_2]/dt)/d[PKC_basal_a] = 0;
(d[MKP_2]/dt)/d[PKC_AA_a] = 0;
(d[MKP_2]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP_2]/dt)/d[PKC_DAG] = 0;
(d[MKP_2]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP_2]/dt)/d[PKC_cytosolic] = 0;
(d[MKP_2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP_2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP_2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP_2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP_2]/dt)/d[MAPKK_RGR] = 0;
(d[MKP_2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP_2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MKP_2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MKP_2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MKP_2]/dt)/d[craf_1] = 0;
(d[MKP_2]/dt)/d[craf_1_a] = 0;
(d[MKP_2]/dt)/d[MAPKK] = 0;
(d[MKP_2]/dt)/d[MAPK] = 0;
(d[MKP_2]/dt)/d[craf_1_a_a] = 0;
(d[MKP_2]/dt)/d[MAPK_tyr] = -(74.999 * MKP_2);
(d[MKP_2]/dt)/d[MAPKK_a] = 0;
(d[MKP_2]/dt)/d[MAPKK_ser] = 0;
(d[MKP_2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP_2]/dt)/d[RGR] = 0;
(d[MKP_2]/dt)/d[Ubiquitination] = 0;
(d[MKP_2]/dt)/d[MKP_1_ser359_a] = 0;
(d[MKP_2]/dt)/d[MKP_1_a_a] = 0;
(d[MKP_2]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP_2]/dt)/d[MKP1_RNA] = 0;
(d[MKP_2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP_2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP_2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP_2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP_2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP_2]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP_2]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP_2]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP_2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP_2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP_2]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP_2]/dt)/d[PLA2_a] = 0;
(d[MKP_2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP_2]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP_2]/dt)/d[inact_GEF] = 0;
(d[MKP_2]/dt)/d[GEF_a] = 0;
(d[MKP_2]/dt)/d[GTP_Ras] = 0;
(d[MKP_2]/dt)/d[GDP_Ras] = 0;
(d[MKP_2]/dt)/d[GAP_a] = 0;
(d[MKP_2]/dt)/d[GAP] = 0;
(d[MKP_2]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP_2]/dt)/d[PDGFR] = 0;
(d[MKP_2]/dt)/d[L_PDGFR] = 0;
(d[MKP_2]/dt)/d[SHC] = 0;
(d[MKP_2]/dt)/d[SHC_a] = 0;
(d[MKP_2]/dt)/d[Internal_L_PDGFR] = 0;
# Sos_a_Grb2:
(d[Sos_a_Grb2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Sos_a_Grb2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Sos_a_Grb2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Sos_a_Grb2]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Sos_a_Grb2]/dt)/d[AA] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP_1] = 0;
(d[Sos_a_Grb2]/dt)/d[PPhosphatase2A] = 0;
(d[Sos_a_Grb2]/dt)/d[tot_MKP1] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP_2] = 0;
(d[Sos_a_Grb2]/dt)/d[Sos_a_Grb2] = -0.0168;
(d[Sos_a_Grb2]/dt)/d[Grb2] = 0.025 * Sos_a;
(d[Sos_a_Grb2]/dt)/d[Sos_Grb2] = 0;
(d[Sos_a_Grb2]/dt)/d[Sos_a] = 0.025 * Grb2;
(d[Sos_a_Grb2]/dt)/d[Sos] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_Ca] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_basal_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_AA_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_Ca_DAG] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_DAG] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_DAG_AA] = 0;
(d[Sos_a_Grb2]/dt)/d[PKC_cytosolic] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_RGR] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Sos_a_Grb2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK] = 0;
(d[Sos_a_Grb2]/dt)/d[craf_1_a_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPK_tyr] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MAPKK_ser] = 0;
(d[Sos_a_Grb2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Sos_a_Grb2]/dt)/d[RGR] = 0;
(d[Sos_a_Grb2]/dt)/d[Ubiquitination] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP_1_ser359_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP_1_a_a] = 0;
(d[Sos_a_Grb2]/dt)/d[nuc_MAPK_a] = 0;
(d[Sos_a_Grb2]/dt)/d[MKP1_RNA] = 0;
(d[Sos_a_Grb2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Sos_a_Grb2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Sos_a_Grb2]/dt)/d[PLA2_cytosolic] = 0;
(d[Sos_a_Grb2]/dt)/d[PLA2_Ca_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PIP2_PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[PLA2_a_Ca] = 0;
(d[Sos_a_Grb2]/dt)/d[PLA2_a] = 0;
(d[Sos_a_Grb2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Sos_a_Grb2]/dt)/d[GTP_Ras_GAP] = 0;
(d[Sos_a_Grb2]/dt)/d[inact_GEF] = 0;
(d[Sos_a_Grb2]/dt)/d[GEF_a] = 0;
(d[Sos_a_Grb2]/dt)/d[GTP_Ras] = 0;
(d[Sos_a_Grb2]/dt)/d[GDP_Ras] = 0;
(d[Sos_a_Grb2]/dt)/d[GAP_a] = 0;
(d[Sos_a_Grb2]/dt)/d[GAP] = 0;
(d[Sos_a_Grb2]/dt)/d[SHC_L_PDGFR] = 0;
(d[Sos_a_Grb2]/dt)/d[PDGFR] = 0;
(d[Sos_a_Grb2]/dt)/d[L_PDGFR] = 0;
(d[Sos_a_Grb2]/dt)/d[SHC] = 0;
(d[Sos_a_Grb2]/dt)/d[SHC_a] = 0;
(d[Sos_a_Grb2]/dt)/d[Internal_L_PDGFR] = 0;
# Grb2:
(d[Grb2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Grb2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Grb2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Grb2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Grb2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Grb2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Grb2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Grb2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Grb2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Grb2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Grb2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Grb2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Grb2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Grb2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Grb2]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Grb2]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Grb2]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Grb2]/dt)/d[AA] = 0;
(d[Grb2]/dt)/d[MAPK_a] = 0;
(d[Grb2]/dt)/d[MKP_1] = 0;
(d[Grb2]/dt)/d[PPhosphatase2A] = 0;
(d[Grb2]/dt)/d[tot_MKP1] = 0;
(d[Grb2]/dt)/d[MKP_2] = 0;
(d[Grb2]/dt)/d[Sos_a_Grb2] = 0.0168;
(d[Grb2]/dt)/d[Grb2] = -(0.025 * Sos_a) - 0.025 * Sos;
(d[Grb2]/dt)/d[Sos_Grb2] = --0.0168;
(d[Grb2]/dt)/d[Sos_a] = -(0.025 * Grb2);
(d[Grb2]/dt)/d[Sos] = -(0.025 * Grb2);
(d[Grb2]/dt)/d[PKC_Ca] = 0;
(d[Grb2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Grb2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Grb2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Grb2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Grb2]/dt)/d[PKC_basal_a] = 0;
(d[Grb2]/dt)/d[PKC_AA_a] = 0;
(d[Grb2]/dt)/d[PKC_Ca_DAG] = 0;
(d[Grb2]/dt)/d[PKC_DAG] = 0;
(d[Grb2]/dt)/d[PKC_DAG_AA] = 0;
(d[Grb2]/dt)/d[PKC_cytosolic] = 0;
(d[Grb2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Grb2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Grb2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Grb2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Grb2]/dt)/d[MAPKK_RGR] = 0;
(d[Grb2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Grb2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Grb2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Grb2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Grb2]/dt)/d[craf_1] = 0;
(d[Grb2]/dt)/d[craf_1_a] = 0;
(d[Grb2]/dt)/d[MAPKK] = 0;
(d[Grb2]/dt)/d[MAPK] = 0;
(d[Grb2]/dt)/d[craf_1_a_a] = 0;
(d[Grb2]/dt)/d[MAPK_tyr] = 0;
(d[Grb2]/dt)/d[MAPKK_a] = 0;
(d[Grb2]/dt)/d[MAPKK_ser] = 0;
(d[Grb2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Grb2]/dt)/d[RGR] = 0;
(d[Grb2]/dt)/d[Ubiquitination] = 0;
(d[Grb2]/dt)/d[MKP_1_ser359_a] = 0;
(d[Grb2]/dt)/d[MKP_1_a_a] = 0;
(d[Grb2]/dt)/d[nuc_MAPK_a] = 0;
(d[Grb2]/dt)/d[MKP1_RNA] = 0;
(d[Grb2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Grb2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Grb2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Grb2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Grb2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Grb2]/dt)/d[PLA2_cytosolic] = 0;
(d[Grb2]/dt)/d[PLA2_Ca_a] = 0;
(d[Grb2]/dt)/d[PIP2_PLA2_a] = 0;
(d[Grb2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Grb2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Grb2]/dt)/d[PLA2_a_Ca] = 0;
(d[Grb2]/dt)/d[PLA2_a] = 0;
(d[Grb2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Grb2]/dt)/d[GTP_Ras_GAP] = 0;
(d[Grb2]/dt)/d[inact_GEF] = 0;
(d[Grb2]/dt)/d[GEF_a] = 0;
(d[Grb2]/dt)/d[GTP_Ras] = 0;
(d[Grb2]/dt)/d[GDP_Ras] = 0;
(d[Grb2]/dt)/d[GAP_a] = 0;
(d[Grb2]/dt)/d[GAP] = 0;
(d[Grb2]/dt)/d[SHC_L_PDGFR] = 0;
(d[Grb2]/dt)/d[PDGFR] = 0;
(d[Grb2]/dt)/d[L_PDGFR] = 0;
(d[Grb2]/dt)/d[SHC] = 0;
(d[Grb2]/dt)/d[SHC_a] = 0;
(d[Grb2]/dt)/d[Internal_L_PDGFR] = 0;
# Sos_Grb2:
(d[Sos_Grb2]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Sos_Grb2]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Sos_Grb2]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Sos_Grb2]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Sos_Grb2]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Sos_Grb2]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Sos_Grb2]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Sos_Grb2]/dt)/d[Shc_a_Sos_Grb2] = 0.1;
(d[Sos_Grb2]/dt)/d[AA] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[MKP_1] = 0;
(d[Sos_Grb2]/dt)/d[PPhosphatase2A] = 0;
(d[Sos_Grb2]/dt)/d[tot_MKP1] = 0;
(d[Sos_Grb2]/dt)/d[MKP_2] = 0;
(d[Sos_Grb2]/dt)/d[Sos_a_Grb2] = 0;
(d[Sos_Grb2]/dt)/d[Grb2] = 0.025 * Sos;
(d[Sos_Grb2]/dt)/d[Sos_Grb2] = -(0.49998 * SHC_a) + -0.0168;
(d[Sos_Grb2]/dt)/d[Sos_a] = 0;
(d[Sos_Grb2]/dt)/d[Sos] = 0.025 * Grb2;
(d[Sos_Grb2]/dt)/d[PKC_Ca] = 0;
(d[Sos_Grb2]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Sos_Grb2]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Sos_Grb2]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Sos_Grb2]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Sos_Grb2]/dt)/d[PKC_basal_a] = 0;
(d[Sos_Grb2]/dt)/d[PKC_AA_a] = 0;
(d[Sos_Grb2]/dt)/d[PKC_Ca_DAG] = 0;
(d[Sos_Grb2]/dt)/d[PKC_DAG] = 0;
(d[Sos_Grb2]/dt)/d[PKC_DAG_AA] = 0;
(d[Sos_Grb2]/dt)/d[PKC_cytosolic] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_RGR] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Sos_Grb2]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[craf_1] = 0;
(d[Sos_Grb2]/dt)/d[craf_1_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK] = 0;
(d[Sos_Grb2]/dt)/d[MAPK] = 0;
(d[Sos_Grb2]/dt)/d[craf_1_a_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPK_tyr] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_a] = 0;
(d[Sos_Grb2]/dt)/d[MAPKK_ser] = 0;
(d[Sos_Grb2]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Sos_Grb2]/dt)/d[RGR] = 0;
(d[Sos_Grb2]/dt)/d[Ubiquitination] = 0;
(d[Sos_Grb2]/dt)/d[MKP_1_ser359_a] = 0;
(d[Sos_Grb2]/dt)/d[MKP_1_a_a] = 0;
(d[Sos_Grb2]/dt)/d[nuc_MAPK_a] = 0;
(d[Sos_Grb2]/dt)/d[MKP1_RNA] = 0;
(d[Sos_Grb2]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Sos_Grb2]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Sos_Grb2]/dt)/d[PLA2_cytosolic] = 0;
(d[Sos_Grb2]/dt)/d[PLA2_Ca_a] = 0;
(d[Sos_Grb2]/dt)/d[PIP2_PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[PLA2_a_Ca] = 0;
(d[Sos_Grb2]/dt)/d[PLA2_a] = 0;
(d[Sos_Grb2]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Sos_Grb2]/dt)/d[GTP_Ras_GAP] = 0;
(d[Sos_Grb2]/dt)/d[inact_GEF] = 0;
(d[Sos_Grb2]/dt)/d[GEF_a] = 0;
(d[Sos_Grb2]/dt)/d[GTP_Ras] = 0;
(d[Sos_Grb2]/dt)/d[GDP_Ras] = 0;
(d[Sos_Grb2]/dt)/d[GAP_a] = 0;
(d[Sos_Grb2]/dt)/d[GAP] = 0;
(d[Sos_Grb2]/dt)/d[SHC_L_PDGFR] = 0;
(d[Sos_Grb2]/dt)/d[PDGFR] = 0;
(d[Sos_Grb2]/dt)/d[L_PDGFR] = 0;
(d[Sos_Grb2]/dt)/d[SHC] = 0;
(d[Sos_Grb2]/dt)/d[SHC_a] = -(0.49998 * Sos_Grb2);
(d[Sos_Grb2]/dt)/d[Internal_L_PDGFR] = 0;
# Sos_a:
(d[Sos_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Sos_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Sos_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Sos_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Sos_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Sos_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Sos_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Sos_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Sos_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Sos_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Sos_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Sos_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Sos_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Sos_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Sos_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Sos_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Sos_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Sos_a]/dt)/d[AA] = 0;
(d[Sos_a]/dt)/d[MAPK_a] = 0;
(d[Sos_a]/dt)/d[MKP_1] = 0;
(d[Sos_a]/dt)/d[PPhosphatase2A] = 0;
(d[Sos_a]/dt)/d[tot_MKP1] = 0;
(d[Sos_a]/dt)/d[MKP_2] = 0;
(d[Sos_a]/dt)/d[Sos_a_Grb2] = 0.0168;
(d[Sos_a]/dt)/d[Grb2] = -(0.025 * Sos_a);
(d[Sos_a]/dt)/d[Sos_Grb2] = 0;
(d[Sos_a]/dt)/d[Sos_a] = -(0.025 * Grb2) - 0.001;
(d[Sos_a]/dt)/d[Sos] = 0;
(d[Sos_a]/dt)/d[PKC_Ca] = 0;
(d[Sos_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Sos_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Sos_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Sos_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Sos_a]/dt)/d[PKC_basal_a] = 0;
(d[Sos_a]/dt)/d[PKC_AA_a] = 0;
(d[Sos_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[Sos_a]/dt)/d[PKC_DAG] = 0;
(d[Sos_a]/dt)/d[PKC_DAG_AA] = 0;
(d[Sos_a]/dt)/d[PKC_cytosolic] = 0;
(d[Sos_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Sos_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Sos_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Sos_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Sos_a]/dt)/d[MAPKK_RGR] = 0;
(d[Sos_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Sos_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Sos_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Sos_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Sos_a]/dt)/d[craf_1] = 0;
(d[Sos_a]/dt)/d[craf_1_a] = 0;
(d[Sos_a]/dt)/d[MAPKK] = 0;
(d[Sos_a]/dt)/d[MAPK] = 0;
(d[Sos_a]/dt)/d[craf_1_a_a] = 0;
(d[Sos_a]/dt)/d[MAPK_tyr] = 0;
(d[Sos_a]/dt)/d[MAPKK_a] = 0;
(d[Sos_a]/dt)/d[MAPKK_ser] = 0;
(d[Sos_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Sos_a]/dt)/d[RGR] = 0;
(d[Sos_a]/dt)/d[Ubiquitination] = 0;
(d[Sos_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[Sos_a]/dt)/d[MKP_1_a_a] = 0;
(d[Sos_a]/dt)/d[nuc_MAPK_a] = 0;
(d[Sos_a]/dt)/d[MKP1_RNA] = 0;
(d[Sos_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Sos_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Sos_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Sos_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Sos_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Sos_a]/dt)/d[PLA2_cytosolic] = 0;
(d[Sos_a]/dt)/d[PLA2_Ca_a] = 0;
(d[Sos_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[Sos_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Sos_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Sos_a]/dt)/d[PLA2_a_Ca] = 0;
(d[Sos_a]/dt)/d[PLA2_a] = 0;
(d[Sos_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Sos_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[Sos_a]/dt)/d[inact_GEF] = 0;
(d[Sos_a]/dt)/d[GEF_a] = 0;
(d[Sos_a]/dt)/d[GTP_Ras] = 0;
(d[Sos_a]/dt)/d[GDP_Ras] = 0;
(d[Sos_a]/dt)/d[GAP_a] = 0;
(d[Sos_a]/dt)/d[GAP] = 0;
(d[Sos_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[Sos_a]/dt)/d[PDGFR] = 0;
(d[Sos_a]/dt)/d[L_PDGFR] = 0;
(d[Sos_a]/dt)/d[SHC] = 0;
(d[Sos_a]/dt)/d[SHC_a] = 0;
(d[Sos_a]/dt)/d[Internal_L_PDGFR] = 0;
# Sos:
(d[Sos]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Sos]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Sos]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Sos]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Sos]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Sos]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Sos]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Sos]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Sos]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Sos]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Sos]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Sos]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Sos]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Sos]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Sos]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Sos]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Sos]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Sos]/dt)/d[AA] = 0;
(d[Sos]/dt)/d[MAPK_a] = 0;
(d[Sos]/dt)/d[MKP_1] = 0;
(d[Sos]/dt)/d[PPhosphatase2A] = 0;
(d[Sos]/dt)/d[tot_MKP1] = 0;
(d[Sos]/dt)/d[MKP_2] = 0;
(d[Sos]/dt)/d[Sos_a_Grb2] = 0;
(d[Sos]/dt)/d[Grb2] = -(0.025 * Sos);
(d[Sos]/dt)/d[Sos_Grb2] = --0.0168;
(d[Sos]/dt)/d[Sos_a] = 0.001;
(d[Sos]/dt)/d[Sos] = -(0.025 * Grb2);
(d[Sos]/dt)/d[PKC_Ca] = 0;
(d[Sos]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Sos]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Sos]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Sos]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Sos]/dt)/d[PKC_basal_a] = 0;
(d[Sos]/dt)/d[PKC_AA_a] = 0;
(d[Sos]/dt)/d[PKC_Ca_DAG] = 0;
(d[Sos]/dt)/d[PKC_DAG] = 0;
(d[Sos]/dt)/d[PKC_DAG_AA] = 0;
(d[Sos]/dt)/d[PKC_cytosolic] = 0;
(d[Sos]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Sos]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Sos]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Sos]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Sos]/dt)/d[MAPKK_RGR] = 0;
(d[Sos]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Sos]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Sos]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Sos]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Sos]/dt)/d[craf_1] = 0;
(d[Sos]/dt)/d[craf_1_a] = 0;
(d[Sos]/dt)/d[MAPKK] = 0;
(d[Sos]/dt)/d[MAPK] = 0;
(d[Sos]/dt)/d[craf_1_a_a] = 0;
(d[Sos]/dt)/d[MAPK_tyr] = 0;
(d[Sos]/dt)/d[MAPKK_a] = 0;
(d[Sos]/dt)/d[MAPKK_ser] = 0;
(d[Sos]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Sos]/dt)/d[RGR] = 0;
(d[Sos]/dt)/d[Ubiquitination] = 0;
(d[Sos]/dt)/d[MKP_1_ser359_a] = 0;
(d[Sos]/dt)/d[MKP_1_a_a] = 0;
(d[Sos]/dt)/d[nuc_MAPK_a] = 0;
(d[Sos]/dt)/d[MKP1_RNA] = 0;
(d[Sos]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Sos]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Sos]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Sos]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Sos]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Sos]/dt)/d[PLA2_cytosolic] = 0;
(d[Sos]/dt)/d[PLA2_Ca_a] = 0;
(d[Sos]/dt)/d[PIP2_PLA2_a] = 0;
(d[Sos]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Sos]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Sos]/dt)/d[PLA2_a_Ca] = 0;
(d[Sos]/dt)/d[PLA2_a] = 0;
(d[Sos]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Sos]/dt)/d[GTP_Ras_GAP] = 0;
(d[Sos]/dt)/d[inact_GEF] = 0;
(d[Sos]/dt)/d[GEF_a] = 0;
(d[Sos]/dt)/d[GTP_Ras] = 0;
(d[Sos]/dt)/d[GDP_Ras] = 0;
(d[Sos]/dt)/d[GAP_a] = 0;
(d[Sos]/dt)/d[GAP] = 0;
(d[Sos]/dt)/d[SHC_L_PDGFR] = 0;
(d[Sos]/dt)/d[PDGFR] = 0;
(d[Sos]/dt)/d[L_PDGFR] = 0;
(d[Sos]/dt)/d[SHC] = 0;
(d[Sos]/dt)/d[SHC_a] = 0;
(d[Sos]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_Ca:
(d[PKC_Ca]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_Ca]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_Ca]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_Ca]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_Ca]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_Ca]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_Ca]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_Ca]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_Ca]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_Ca]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca]/dt)/d[AA] = -(0.0012 * PKC_Ca);
(d[PKC_Ca]/dt)/d[MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[MKP_1] = 0;
(d[PKC_Ca]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_Ca]/dt)/d[tot_MKP1] = 0;
(d[PKC_Ca]/dt)/d[MKP_2] = 0;
(d[PKC_Ca]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_Ca]/dt)/d[Grb2] = 0;
(d[PKC_Ca]/dt)/d[Sos_Grb2] = 0;
(d[PKC_Ca]/dt)/d[Sos_a] = 0;
(d[PKC_Ca]/dt)/d[Sos] = 0;
(d[PKC_Ca]/dt)/d[PKC_Ca] = -0.5 - 0.0932856678 - 1.2705 - 0.0012 * AA;
(d[PKC_Ca]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_Ca]/dt)/d[PKC_Ca_AA_a] = --0.1;
(d[PKC_Ca]/dt)/d[PKC_Ca_memb_a] = --3.5026;
(d[PKC_Ca]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_Ca]/dt)/d[PKC_basal_a] = 0;
(d[PKC_Ca]/dt)/d[PKC_AA_a] = 0;
(d[PKC_Ca]/dt)/d[PKC_Ca_DAG] = --8.6348;
(d[PKC_Ca]/dt)/d[PKC_DAG] = 0;
(d[PKC_Ca]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_Ca]/dt)/d[PKC_cytosolic] = 0.6 * 0.08;
(d[PKC_Ca]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_Ca]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_Ca]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_Ca]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_Ca]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[craf_1] = 0;
(d[PKC_Ca]/dt)/d[craf_1_a] = 0;
(d[PKC_Ca]/dt)/d[MAPKK] = 0;
(d[PKC_Ca]/dt)/d[MAPK] = 0;
(d[PKC_Ca]/dt)/d[craf_1_a_a] = 0;
(d[PKC_Ca]/dt)/d[MAPK_tyr] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_a] = 0;
(d[PKC_Ca]/dt)/d[MAPKK_ser] = 0;
(d[PKC_Ca]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_Ca]/dt)/d[RGR] = 0;
(d[PKC_Ca]/dt)/d[Ubiquitination] = 0;
(d[PKC_Ca]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_Ca]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_Ca]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_Ca]/dt)/d[MKP1_RNA] = 0;
(d[PKC_Ca]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_Ca]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_Ca]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_Ca]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_Ca]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_Ca]/dt)/d[PLA2_a] = 0;
(d[PKC_Ca]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_Ca]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_Ca]/dt)/d[inact_GEF] = 0;
(d[PKC_Ca]/dt)/d[GEF_a] = 0;
(d[PKC_Ca]/dt)/d[GTP_Ras] = 0;
(d[PKC_Ca]/dt)/d[GDP_Ras] = 0;
(d[PKC_Ca]/dt)/d[GAP_a] = 0;
(d[PKC_Ca]/dt)/d[GAP] = 0;
(d[PKC_Ca]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_Ca]/dt)/d[PDGFR] = 0;
(d[PKC_Ca]/dt)/d[L_PDGFR] = 0;
(d[PKC_Ca]/dt)/d[SHC] = 0;
(d[PKC_Ca]/dt)/d[SHC_a] = 0;
(d[PKC_Ca]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_DAG_AA_a:
(d[PKC_DAG_AA_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_DAG_AA_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[AA] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP_1] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_DAG_AA_a]/dt)/d[tot_MKP1] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP_2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Grb2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Sos_Grb2] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Sos_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Sos] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_Ca] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_DAG_AA_a] = -0.2;
(d[PKC_DAG_AA_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_basal_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_AA_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_DAG] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PKC_DAG_AA] = 2;
(d[PKC_DAG_AA_a]/dt)/d[PKC_cytosolic] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK] = 0;
(d[PKC_DAG_AA_a]/dt)/d[craf_1_a_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPK_tyr] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MAPKK_ser] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[RGR] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Ubiquitination] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[MKP1_RNA] = 0;
(d[PKC_DAG_AA_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PLA2_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_DAG_AA_a]/dt)/d[inact_GEF] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GEF_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GTP_Ras] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GDP_Ras] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GAP_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[GAP] = 0;
(d[PKC_DAG_AA_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_DAG_AA_a]/dt)/d[PDGFR] = 0;
(d[PKC_DAG_AA_a]/dt)/d[L_PDGFR] = 0;
(d[PKC_DAG_AA_a]/dt)/d[SHC] = 0;
(d[PKC_DAG_AA_a]/dt)/d[SHC_a] = 0;
(d[PKC_DAG_AA_a]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_Ca_AA_a:
(d[PKC_Ca_AA_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_Ca_AA_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[AA] = 0.0012 * PKC_Ca;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP_1] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_Ca_AA_a]/dt)/d[tot_MKP1] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP_2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Grb2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Sos_Grb2] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Sos_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Sos] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_Ca] = 0.0012 * AA;
(d[PKC_Ca_AA_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_Ca_AA_a] = -0.1;
(d[PKC_Ca_AA_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_basal_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_AA_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_DAG] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PKC_cytosolic] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK] = 0;
(d[PKC_Ca_AA_a]/dt)/d[craf_1_a_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPK_tyr] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MAPKK_ser] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[RGR] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Ubiquitination] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[MKP1_RNA] = 0;
(d[PKC_Ca_AA_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PLA2_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_Ca_AA_a]/dt)/d[inact_GEF] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GEF_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GTP_Ras] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GDP_Ras] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GAP_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[GAP] = 0;
(d[PKC_Ca_AA_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_Ca_AA_a]/dt)/d[PDGFR] = 0;
(d[PKC_Ca_AA_a]/dt)/d[L_PDGFR] = 0;
(d[PKC_Ca_AA_a]/dt)/d[SHC] = 0;
(d[PKC_Ca_AA_a]/dt)/d[SHC_a] = 0;
(d[PKC_Ca_AA_a]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_Ca_memb_a:
(d[PKC_Ca_memb_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_Ca_memb_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[AA] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP_1] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_Ca_memb_a]/dt)/d[tot_MKP1] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP_2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Grb2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Sos_Grb2] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Sos_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Sos] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_Ca] = 1.2705;
(d[PKC_Ca_memb_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_Ca_memb_a] = -3.5026;
(d[PKC_Ca_memb_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_basal_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_AA_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_DAG] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PKC_cytosolic] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK] = 0;
(d[PKC_Ca_memb_a]/dt)/d[craf_1_a_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPK_tyr] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MAPKK_ser] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[RGR] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Ubiquitination] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[MKP1_RNA] = 0;
(d[PKC_Ca_memb_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PLA2_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_Ca_memb_a]/dt)/d[inact_GEF] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GEF_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GTP_Ras] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GDP_Ras] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GAP_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[GAP] = 0;
(d[PKC_Ca_memb_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_Ca_memb_a]/dt)/d[PDGFR] = 0;
(d[PKC_Ca_memb_a]/dt)/d[L_PDGFR] = 0;
(d[PKC_Ca_memb_a]/dt)/d[SHC] = 0;
(d[PKC_Ca_memb_a]/dt)/d[SHC_a] = 0;
(d[PKC_Ca_memb_a]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_DAG_memb_a:
(d[PKC_DAG_memb_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_DAG_memb_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[AA] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP_1] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_DAG_memb_a]/dt)/d[tot_MKP1] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP_2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Grb2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Sos_Grb2] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Sos_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Sos] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_Ca] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_DAG_memb_a] = -0.1;
(d[PKC_DAG_memb_a]/dt)/d[PKC_basal_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_AA_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_Ca_DAG] = 1;
(d[PKC_DAG_memb_a]/dt)/d[PKC_DAG] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PKC_cytosolic] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK] = 0;
(d[PKC_DAG_memb_a]/dt)/d[craf_1_a_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPK_tyr] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MAPKK_ser] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[RGR] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Ubiquitination] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[MKP1_RNA] = 0;
(d[PKC_DAG_memb_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PLA2_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_DAG_memb_a]/dt)/d[inact_GEF] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GEF_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GTP_Ras] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GDP_Ras] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GAP_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[GAP] = 0;
(d[PKC_DAG_memb_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_DAG_memb_a]/dt)/d[PDGFR] = 0;
(d[PKC_DAG_memb_a]/dt)/d[L_PDGFR] = 0;
(d[PKC_DAG_memb_a]/dt)/d[SHC] = 0;
(d[PKC_DAG_memb_a]/dt)/d[SHC_a] = 0;
(d[PKC_DAG_memb_a]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_basal_a:
(d[PKC_basal_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_basal_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_basal_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_basal_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_basal_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_basal_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_basal_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_basal_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_basal_a]/dt)/d[AA] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[MKP_1] = 0;
(d[PKC_basal_a]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_basal_a]/dt)/d[tot_MKP1] = 0;
(d[PKC_basal_a]/dt)/d[MKP_2] = 0;
(d[PKC_basal_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_basal_a]/dt)/d[Grb2] = 0;
(d[PKC_basal_a]/dt)/d[Sos_Grb2] = 0;
(d[PKC_basal_a]/dt)/d[Sos_a] = 0;
(d[PKC_basal_a]/dt)/d[Sos] = 0;
(d[PKC_basal_a]/dt)/d[PKC_Ca] = 0;
(d[PKC_basal_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_basal_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_basal_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_basal_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_basal_a]/dt)/d[PKC_basal_a] = -50;
(d[PKC_basal_a]/dt)/d[PKC_AA_a] = 0;
(d[PKC_basal_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_basal_a]/dt)/d[PKC_DAG] = 0;
(d[PKC_basal_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_basal_a]/dt)/d[PKC_cytosolic] = 1;
(d[PKC_basal_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_basal_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[craf_1] = 0;
(d[PKC_basal_a]/dt)/d[craf_1_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK] = 0;
(d[PKC_basal_a]/dt)/d[MAPK] = 0;
(d[PKC_basal_a]/dt)/d[craf_1_a_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPK_tyr] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_a] = 0;
(d[PKC_basal_a]/dt)/d[MAPKK_ser] = 0;
(d[PKC_basal_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_basal_a]/dt)/d[RGR] = 0;
(d[PKC_basal_a]/dt)/d[Ubiquitination] = 0;
(d[PKC_basal_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_basal_a]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_basal_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_basal_a]/dt)/d[MKP1_RNA] = 0;
(d[PKC_basal_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_basal_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_basal_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_basal_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_basal_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_basal_a]/dt)/d[PLA2_a] = 0;
(d[PKC_basal_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_basal_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_basal_a]/dt)/d[inact_GEF] = 0;
(d[PKC_basal_a]/dt)/d[GEF_a] = 0;
(d[PKC_basal_a]/dt)/d[GTP_Ras] = 0;
(d[PKC_basal_a]/dt)/d[GDP_Ras] = 0;
(d[PKC_basal_a]/dt)/d[GAP_a] = 0;
(d[PKC_basal_a]/dt)/d[GAP] = 0;
(d[PKC_basal_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_basal_a]/dt)/d[PDGFR] = 0;
(d[PKC_basal_a]/dt)/d[L_PDGFR] = 0;
(d[PKC_basal_a]/dt)/d[SHC] = 0;
(d[PKC_basal_a]/dt)/d[SHC_a] = 0;
(d[PKC_basal_a]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_AA_a:
(d[PKC_AA_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_AA_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_AA_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_AA_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_AA_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_AA_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_AA_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_AA_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_AA_a]/dt)/d[AA] = 0.00012 * PKC_cytosolic;
(d[PKC_AA_a]/dt)/d[MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[MKP_1] = 0;
(d[PKC_AA_a]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_AA_a]/dt)/d[tot_MKP1] = 0;
(d[PKC_AA_a]/dt)/d[MKP_2] = 0;
(d[PKC_AA_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_AA_a]/dt)/d[Grb2] = 0;
(d[PKC_AA_a]/dt)/d[Sos_Grb2] = 0;
(d[PKC_AA_a]/dt)/d[Sos_a] = 0;
(d[PKC_AA_a]/dt)/d[Sos] = 0;
(d[PKC_AA_a]/dt)/d[PKC_Ca] = 0;
(d[PKC_AA_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_AA_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_AA_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_AA_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_AA_a]/dt)/d[PKC_basal_a] = 0;
(d[PKC_AA_a]/dt)/d[PKC_AA_a] = -0.1;
(d[PKC_AA_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_AA_a]/dt)/d[PKC_DAG] = 0;
(d[PKC_AA_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_AA_a]/dt)/d[PKC_cytosolic] = 0.00012 * AA;
(d[PKC_AA_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_AA_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[craf_1] = 0;
(d[PKC_AA_a]/dt)/d[craf_1_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK] = 0;
(d[PKC_AA_a]/dt)/d[MAPK] = 0;
(d[PKC_AA_a]/dt)/d[craf_1_a_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPK_tyr] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_a] = 0;
(d[PKC_AA_a]/dt)/d[MAPKK_ser] = 0;
(d[PKC_AA_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_AA_a]/dt)/d[RGR] = 0;
(d[PKC_AA_a]/dt)/d[Ubiquitination] = 0;
(d[PKC_AA_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_AA_a]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_AA_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_AA_a]/dt)/d[MKP1_RNA] = 0;
(d[PKC_AA_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_AA_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_AA_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_AA_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_AA_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_AA_a]/dt)/d[PLA2_a] = 0;
(d[PKC_AA_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_AA_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_AA_a]/dt)/d[inact_GEF] = 0;
(d[PKC_AA_a]/dt)/d[GEF_a] = 0;
(d[PKC_AA_a]/dt)/d[GTP_Ras] = 0;
(d[PKC_AA_a]/dt)/d[GDP_Ras] = 0;
(d[PKC_AA_a]/dt)/d[GAP_a] = 0;
(d[PKC_AA_a]/dt)/d[GAP] = 0;
(d[PKC_AA_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_AA_a]/dt)/d[PDGFR] = 0;
(d[PKC_AA_a]/dt)/d[L_PDGFR] = 0;
(d[PKC_AA_a]/dt)/d[SHC] = 0;
(d[PKC_AA_a]/dt)/d[SHC_a] = 0;
(d[PKC_AA_a]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_Ca_DAG:
(d[PKC_Ca_DAG]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_Ca_DAG]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_Ca_DAG]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_Ca_DAG]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_Ca_DAG]/dt)/d[AA] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP_1] = 0;
(d[PKC_Ca_DAG]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_Ca_DAG]/dt)/d[tot_MKP1] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP_2] = 0;
(d[PKC_Ca_DAG]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_Ca_DAG]/dt)/d[Grb2] = 0;
(d[PKC_Ca_DAG]/dt)/d[Sos_Grb2] = 0;
(d[PKC_Ca_DAG]/dt)/d[Sos_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[Sos] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_Ca] = 0.0932856678;
(d[PKC_Ca_DAG]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_DAG_memb_a] = --0.1;
(d[PKC_Ca_DAG]/dt)/d[PKC_basal_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_AA_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_Ca_DAG] = -8.6348 - 1;
(d[PKC_Ca_DAG]/dt)/d[PKC_DAG] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_Ca_DAG]/dt)/d[PKC_cytosolic] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK] = 0;
(d[PKC_Ca_DAG]/dt)/d[craf_1_a_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPK_tyr] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MAPKK_ser] = 0;
(d[PKC_Ca_DAG]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[RGR] = 0;
(d[PKC_Ca_DAG]/dt)/d[Ubiquitination] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[MKP1_RNA] = 0;
(d[PKC_Ca_DAG]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_Ca_DAG]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_Ca_DAG]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_Ca_DAG]/dt)/d[PLA2_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_Ca_DAG]/dt)/d[inact_GEF] = 0;
(d[PKC_Ca_DAG]/dt)/d[GEF_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[GTP_Ras] = 0;
(d[PKC_Ca_DAG]/dt)/d[GDP_Ras] = 0;
(d[PKC_Ca_DAG]/dt)/d[GAP_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[GAP] = 0;
(d[PKC_Ca_DAG]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_Ca_DAG]/dt)/d[PDGFR] = 0;
(d[PKC_Ca_DAG]/dt)/d[L_PDGFR] = 0;
(d[PKC_Ca_DAG]/dt)/d[SHC] = 0;
(d[PKC_Ca_DAG]/dt)/d[SHC_a] = 0;
(d[PKC_Ca_DAG]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_DAG:
(d[PKC_DAG]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_DAG]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_DAG]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_DAG]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_DAG]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_DAG]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_DAG]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_DAG]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_DAG]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_DAG]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG]/dt)/d[AA] = -(0.018 * PKC_DAG);
(d[PKC_DAG]/dt)/d[MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[MKP_1] = 0;
(d[PKC_DAG]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_DAG]/dt)/d[tot_MKP1] = 0;
(d[PKC_DAG]/dt)/d[MKP_2] = 0;
(d[PKC_DAG]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_DAG]/dt)/d[Grb2] = 0;
(d[PKC_DAG]/dt)/d[Sos_Grb2] = 0;
(d[PKC_DAG]/dt)/d[Sos_a] = 0;
(d[PKC_DAG]/dt)/d[Sos] = 0;
(d[PKC_DAG]/dt)/d[PKC_Ca] = 0;
(d[PKC_DAG]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_DAG]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_DAG]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_DAG]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_DAG]/dt)/d[PKC_basal_a] = 0;
(d[PKC_DAG]/dt)/d[PKC_AA_a] = 0;
(d[PKC_DAG]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_DAG]/dt)/d[PKC_DAG] = -0.1 - 0.018 * AA;
(d[PKC_DAG]/dt)/d[PKC_DAG_AA] = --2;
(d[PKC_DAG]/dt)/d[PKC_cytosolic] = 0.0006 * 11.661;
(d[PKC_DAG]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_DAG]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_DAG]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_DAG]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_DAG]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[craf_1] = 0;
(d[PKC_DAG]/dt)/d[craf_1_a] = 0;
(d[PKC_DAG]/dt)/d[MAPKK] = 0;
(d[PKC_DAG]/dt)/d[MAPK] = 0;
(d[PKC_DAG]/dt)/d[craf_1_a_a] = 0;
(d[PKC_DAG]/dt)/d[MAPK_tyr] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_a] = 0;
(d[PKC_DAG]/dt)/d[MAPKK_ser] = 0;
(d[PKC_DAG]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_DAG]/dt)/d[RGR] = 0;
(d[PKC_DAG]/dt)/d[Ubiquitination] = 0;
(d[PKC_DAG]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_DAG]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_DAG]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_DAG]/dt)/d[MKP1_RNA] = 0;
(d[PKC_DAG]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_DAG]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_DAG]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_DAG]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_DAG]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_DAG]/dt)/d[PLA2_a] = 0;
(d[PKC_DAG]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_DAG]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_DAG]/dt)/d[inact_GEF] = 0;
(d[PKC_DAG]/dt)/d[GEF_a] = 0;
(d[PKC_DAG]/dt)/d[GTP_Ras] = 0;
(d[PKC_DAG]/dt)/d[GDP_Ras] = 0;
(d[PKC_DAG]/dt)/d[GAP_a] = 0;
(d[PKC_DAG]/dt)/d[GAP] = 0;
(d[PKC_DAG]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_DAG]/dt)/d[PDGFR] = 0;
(d[PKC_DAG]/dt)/d[L_PDGFR] = 0;
(d[PKC_DAG]/dt)/d[SHC] = 0;
(d[PKC_DAG]/dt)/d[SHC_a] = 0;
(d[PKC_DAG]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_DAG_AA:
(d[PKC_DAG_AA]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_DAG_AA]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_DAG_AA]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_DAG_AA]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_DAG_AA]/dt)/d[AA] = 0.018 * PKC_DAG;
(d[PKC_DAG_AA]/dt)/d[MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP_1] = 0;
(d[PKC_DAG_AA]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_DAG_AA]/dt)/d[tot_MKP1] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP_2] = 0;
(d[PKC_DAG_AA]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_DAG_AA]/dt)/d[Grb2] = 0;
(d[PKC_DAG_AA]/dt)/d[Sos_Grb2] = 0;
(d[PKC_DAG_AA]/dt)/d[Sos_a] = 0;
(d[PKC_DAG_AA]/dt)/d[Sos] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_Ca] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_DAG_AA_a] = 0.2;
(d[PKC_DAG_AA]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_basal_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_AA_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_DAG_AA]/dt)/d[PKC_DAG] = 0.018 * AA;
(d[PKC_DAG_AA]/dt)/d[PKC_DAG_AA] = -2 + -2;
(d[PKC_DAG_AA]/dt)/d[PKC_cytosolic] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_DAG_AA]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK] = 0;
(d[PKC_DAG_AA]/dt)/d[craf_1_a_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPK_tyr] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MAPKK_ser] = 0;
(d[PKC_DAG_AA]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_DAG_AA]/dt)/d[RGR] = 0;
(d[PKC_DAG_AA]/dt)/d[Ubiquitination] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_DAG_AA]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_DAG_AA]/dt)/d[MKP1_RNA] = 0;
(d[PKC_DAG_AA]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_DAG_AA]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_DAG_AA]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_DAG_AA]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_DAG_AA]/dt)/d[PLA2_a] = 0;
(d[PKC_DAG_AA]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_DAG_AA]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_DAG_AA]/dt)/d[inact_GEF] = 0;
(d[PKC_DAG_AA]/dt)/d[GEF_a] = 0;
(d[PKC_DAG_AA]/dt)/d[GTP_Ras] = 0;
(d[PKC_DAG_AA]/dt)/d[GDP_Ras] = 0;
(d[PKC_DAG_AA]/dt)/d[GAP_a] = 0;
(d[PKC_DAG_AA]/dt)/d[GAP] = 0;
(d[PKC_DAG_AA]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_DAG_AA]/dt)/d[PDGFR] = 0;
(d[PKC_DAG_AA]/dt)/d[L_PDGFR] = 0;
(d[PKC_DAG_AA]/dt)/d[SHC] = 0;
(d[PKC_DAG_AA]/dt)/d[SHC_a] = 0;
(d[PKC_DAG_AA]/dt)/d[Internal_L_PDGFR] = 0;
# PKC_cytosolic:
(d[PKC_cytosolic]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PKC_cytosolic]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PKC_cytosolic]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PKC_cytosolic]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PKC_cytosolic]/dt)/d[AA] = -(0.00012 * PKC_cytosolic);
(d[PKC_cytosolic]/dt)/d[MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MKP_1] = 0;
(d[PKC_cytosolic]/dt)/d[PPhosphatase2A] = 0;
(d[PKC_cytosolic]/dt)/d[tot_MKP1] = 0;
(d[PKC_cytosolic]/dt)/d[MKP_2] = 0;
(d[PKC_cytosolic]/dt)/d[Sos_a_Grb2] = 0;
(d[PKC_cytosolic]/dt)/d[Grb2] = 0;
(d[PKC_cytosolic]/dt)/d[Sos_Grb2] = 0;
(d[PKC_cytosolic]/dt)/d[Sos_a] = 0;
(d[PKC_cytosolic]/dt)/d[Sos] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_Ca] = 0.5;
(d[PKC_cytosolic]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_basal_a] = --50;
(d[PKC_cytosolic]/dt)/d[PKC_AA_a] = --0.1;
(d[PKC_cytosolic]/dt)/d[PKC_Ca_DAG] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_DAG] = --0.1;
(d[PKC_cytosolic]/dt)/d[PKC_DAG_AA] = 0;
(d[PKC_cytosolic]/dt)/d[PKC_cytosolic] = -0.048 - 1 - 0.00012 * AA - 0.0006 * 11.661;
(d[PKC_cytosolic]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_RGR] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PKC_cytosolic]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK] = 0;
(d[PKC_cytosolic]/dt)/d[craf_1_a_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPK_tyr] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MAPKK_ser] = 0;
(d[PKC_cytosolic]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PKC_cytosolic]/dt)/d[RGR] = 0;
(d[PKC_cytosolic]/dt)/d[Ubiquitination] = 0;
(d[PKC_cytosolic]/dt)/d[MKP_1_ser359_a] = 0;
(d[PKC_cytosolic]/dt)/d[MKP_1_a_a] = 0;
(d[PKC_cytosolic]/dt)/d[nuc_MAPK_a] = 0;
(d[PKC_cytosolic]/dt)/d[MKP1_RNA] = 0;
(d[PKC_cytosolic]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PKC_cytosolic]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PKC_cytosolic]/dt)/d[PLA2_cytosolic] = 0;
(d[PKC_cytosolic]/dt)/d[PLA2_Ca_a] = 0;
(d[PKC_cytosolic]/dt)/d[PIP2_PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[PLA2_a_Ca] = 0;
(d[PKC_cytosolic]/dt)/d[PLA2_a] = 0;
(d[PKC_cytosolic]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PKC_cytosolic]/dt)/d[GTP_Ras_GAP] = 0;
(d[PKC_cytosolic]/dt)/d[inact_GEF] = 0;
(d[PKC_cytosolic]/dt)/d[GEF_a] = 0;
(d[PKC_cytosolic]/dt)/d[GTP_Ras] = 0;
(d[PKC_cytosolic]/dt)/d[GDP_Ras] = 0;
(d[PKC_cytosolic]/dt)/d[GAP_a] = 0;
(d[PKC_cytosolic]/dt)/d[GAP] = 0;
(d[PKC_cytosolic]/dt)/d[SHC_L_PDGFR] = 0;
(d[PKC_cytosolic]/dt)/d[PDGFR] = 0;
(d[PKC_cytosolic]/dt)/d[L_PDGFR] = 0;
(d[PKC_cytosolic]/dt)/d[SHC] = 0;
(d[PKC_cytosolic]/dt)/d[SHC_a] = 0;
(d[PKC_cytosolic]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_MAPKK_a:
(d[MAPK_MAPKK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_MAPKK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_MAPKK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_MAPKK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_MAPKK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[AA] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP_1] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_MAPKK_a]/dt)/d[tot_MKP1] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP_2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Grb2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Sos_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Sos] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_Ca] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_DAG] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_MAPKK_a] = -0.6 - 0.15;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[craf_1] = 0;
(d[MAPK_MAPKK_a]/dt)/d[craf_1_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK] = 16.2 * MAPKK_a;
(d[MAPK_MAPKK_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPK_tyr] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_a] = 16.2 * MAPK;
(d[MAPK_MAPKK_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[RGR] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Ubiquitination] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_MAPKK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PLA2_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_MAPKK_a]/dt)/d[inact_GEF] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GEF_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GTP_Ras] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GDP_Ras] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GAP_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[GAP] = 0;
(d[MAPK_MAPKK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_MAPKK_a]/dt)/d[PDGFR] = 0;
(d[MAPK_MAPKK_a]/dt)/d[L_PDGFR] = 0;
(d[MAPK_MAPKK_a]/dt)/d[SHC] = 0;
(d[MAPK_MAPKK_a]/dt)/d[SHC_a] = 0;
(d[MAPK_MAPKK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_tyr_MAPKK_a:
(d[MAPK_tyr_MAPKK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[AA] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP_1] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[tot_MKP1] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP_2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Grb2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Sos_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Sos] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_Ca] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_DAG] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_tyr_MAPKK_a] = -0.6 - 0.15;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPK_tyr] = 16.2 * MAPKK_a;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_a] = 16.2 * MAPK_tyr;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[RGR] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Ubiquitination] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PLA2_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[inact_GEF] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GEF_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GTP_Ras] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GDP_Ras] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GAP_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[GAP] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[PDGFR] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[L_PDGFR] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[SHC] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[SHC_a] = 0;
(d[MAPK_tyr_MAPKK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_Raf_GTP_Ras_a:
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[AA] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP_1] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP_2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Grb2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Sos_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Sos] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = -0.42 - 0.105;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK] = 3.3 * Raf_GTP_Ras_a;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Raf_GTP_Ras_a] = 3.3 * MAPKK;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[RGR] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PLA2_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[inact_GEF] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GEF_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GAP_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[GAP] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[PDGFR] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[SHC] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[SHC_a] = 0;
(d[MAPKK_Raf_GTP_Ras_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_ser_Raf_GTP_Ras_a:
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[AA] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP_1] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP_2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Grb2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Sos_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Sos] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = -0.42 - 0.105;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MAPKK_ser] = 3.3 * Raf_GTP_Ras_a;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Raf_GTP_Ras_a] = 3.3 * MAPKK_ser;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[RGR] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PLA2_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[inact_GEF] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GEF_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GAP_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[GAP] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[PDGFR] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[SHC] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[SHC_a] = 0;
(d[MAPKK_ser_Raf_GTP_Ras_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_RGR:
(d[MAPKK_RGR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_RGR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_RGR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_RGR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_RGR]/dt)/d[AA] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MKP_1] = 0;
(d[MAPKK_RGR]/dt)/d[PPhosphatase2A] = 0;
(d[MAPKK_RGR]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_RGR]/dt)/d[MKP_2] = 0;
(d[MAPKK_RGR]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_RGR]/dt)/d[Grb2] = 0;
(d[MAPKK_RGR]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_RGR]/dt)/d[Sos_a] = 0;
(d[MAPKK_RGR]/dt)/d[Sos] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_RGR]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_RGR] = -0.42 - 0.105;
(d[MAPKK_RGR]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_RGR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK] = 3.3 * RGR;
(d[MAPKK_RGR]/dt)/d[MAPK] = 0;
(d[MAPKK_RGR]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MAPKK_ser] = 0;
(d[MAPKK_RGR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPKK_RGR]/dt)/d[RGR] = 3.3 * MAPKK;
(d[MAPKK_RGR]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_RGR]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_RGR]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_RGR]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_RGR]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_RGR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_RGR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_RGR]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_RGR]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_RGR]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_RGR]/dt)/d[PLA2_a] = 0;
(d[MAPKK_RGR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_RGR]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_RGR]/dt)/d[inact_GEF] = 0;
(d[MAPKK_RGR]/dt)/d[GEF_a] = 0;
(d[MAPKK_RGR]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_RGR]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_RGR]/dt)/d[GAP_a] = 0;
(d[MAPKK_RGR]/dt)/d[GAP] = 0;
(d[MAPKK_RGR]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_RGR]/dt)/d[PDGFR] = 0;
(d[MAPKK_RGR]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_RGR]/dt)/d[SHC] = 0;
(d[MAPKK_RGR]/dt)/d[SHC_a] = 0;
(d[MAPKK_RGR]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_ser_RGR:
(d[MAPKK_ser_RGR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_ser_RGR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[AA] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP_1] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PPhosphatase2A] = 0;
(d[MAPKK_ser_RGR]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP_2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Grb2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Sos_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Sos] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_RGR] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_ser_RGR] = -0.42 - 0.105;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK] = 0;
(d[MAPKK_ser_RGR]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MAPKK_ser] = 3.3 * RGR;
(d[MAPKK_ser_RGR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[RGR] = 3.3 * MAPKK_ser;
(d[MAPKK_ser_RGR]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_ser_RGR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PLA2_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_ser_RGR]/dt)/d[inact_GEF] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GEF_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GAP_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[GAP] = 0;
(d[MAPKK_ser_RGR]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_ser_RGR]/dt)/d[PDGFR] = 0;
(d[MAPKK_ser_RGR]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_ser_RGR]/dt)/d[SHC] = 0;
(d[MAPKK_ser_RGR]/dt)/d[SHC_a] = 0;
(d[MAPKK_ser_RGR]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_tyr_MKP_1_a_a:
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[AA] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP_1] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[tot_MKP1] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP_2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Grb2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Sos_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Sos] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_Ca] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_DAG] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = -4 - 1;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPK_tyr] = 74.999 * MKP_1_a_a;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[RGR] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Ubiquitination] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP_1_a_a] = 74.999 * MAPK_tyr;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PLA2_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[inact_GEF] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GEF_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GTP_Ras] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GDP_Ras] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GAP_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[GAP] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[PDGFR] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[L_PDGFR] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[SHC] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[SHC_a] = 0;
(d[MAPK_tyr_MKP_1_a_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_a_MKP_1_a_a:
(d[MAPK_a_MKP_1_a_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[AA] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_a] = 74.999 * MKP_1_a_a;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP_1] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[tot_MKP1] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP_2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Grb2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Sos_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Sos] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_Ca] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_DAG] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_a_MKP_1_a_a] = -4 - 1;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPK_tyr] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[RGR] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Ubiquitination] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP_1_a_a] = 74.999 * MAPK_a;
(d[MAPK_a_MKP_1_a_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PLA2_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[inact_GEF] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GEF_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GTP_Ras] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GDP_Ras] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GAP_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[GAP] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[PDGFR] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[L_PDGFR] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[SHC] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[SHC_a] = 0;
(d[MAPK_a_MKP_1_a_a]/dt)/d[Internal_L_PDGFR] = 0;
# Nucleotides_nuc_MAPK_a:
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[AA] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP_1] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP_2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Grb2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Sos_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Sos] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = -0.0032 - 0.0008;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[RGR] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP_1_a_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[nuc_MAPK_a] = 0.0001;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PLA2_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[inact_GEF] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GEF_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GAP_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[GAP] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[PDGFR] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[SHC] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[SHC_a] = 0;
(d[Nucleotides_nuc_MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1:
(d[craf_1]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1]/dt)/d[craf_1_PKC_a_pool] = --16;
(d[craf_1]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[craf_1]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1]/dt)/d[craf_1_a_PPhosphatase2A] = 6;
(d[craf_1]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[craf_1]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1]/dt)/d[AA] = 0;
(d[craf_1]/dt)/d[MAPK_a] = 0;
(d[craf_1]/dt)/d[MKP_1] = 0;
(d[craf_1]/dt)/d[PPhosphatase2A] = 0;
(d[craf_1]/dt)/d[tot_MKP1] = 0;
(d[craf_1]/dt)/d[MKP_2] = 0;
(d[craf_1]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1]/dt)/d[Grb2] = 0;
(d[craf_1]/dt)/d[Sos_Grb2] = 0;
(d[craf_1]/dt)/d[Sos_a] = 0;
(d[craf_1]/dt)/d[Sos] = 0;
(d[craf_1]/dt)/d[PKC_Ca] = 0;
(d[craf_1]/dt)/d[PKC_DAG_AA_a] = -(0.3 * craf_1);
(d[craf_1]/dt)/d[PKC_Ca_AA_a] = -(0.3 * craf_1);
(d[craf_1]/dt)/d[PKC_Ca_memb_a] = -(0.3 * craf_1);
(d[craf_1]/dt)/d[PKC_DAG_memb_a] = -(0.3 * craf_1);
(d[craf_1]/dt)/d[PKC_basal_a] = -(0.3 * craf_1);
(d[craf_1]/dt)/d[PKC_AA_a] = -(0.3 * craf_1);
(d[craf_1]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1]/dt)/d[PKC_DAG] = 0;
(d[craf_1]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1]/dt)/d[craf_1] = -(6 * GTP_Ras) - 0.3 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a);
(d[craf_1]/dt)/d[craf_1_a] = 0;
(d[craf_1]/dt)/d[MAPKK] = 0;
(d[craf_1]/dt)/d[MAPK] = 0;
(d[craf_1]/dt)/d[craf_1_a_a] = 0;
(d[craf_1]/dt)/d[MAPK_tyr] = 0;
(d[craf_1]/dt)/d[MAPKK_a] = 0;
(d[craf_1]/dt)/d[MAPKK_ser] = 0;
(d[craf_1]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[craf_1]/dt)/d[RGR] = 1;
(d[craf_1]/dt)/d[Ubiquitination] = 0;
(d[craf_1]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1]/dt)/d[MKP1_RNA] = 0;
(d[craf_1]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1]/dt)/d[PLA2_a] = 0;
(d[craf_1]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1]/dt)/d[inact_GEF] = 0;
(d[craf_1]/dt)/d[GEF_a] = 0;
(d[craf_1]/dt)/d[GTP_Ras] = -(6 * craf_1);
(d[craf_1]/dt)/d[GDP_Ras] = 0;
(d[craf_1]/dt)/d[GAP_a] = 0;
(d[craf_1]/dt)/d[GAP] = 0;
(d[craf_1]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1]/dt)/d[PDGFR] = 0;
(d[craf_1]/dt)/d[L_PDGFR] = 0;
(d[craf_1]/dt)/d[SHC] = 0;
(d[craf_1]/dt)/d[SHC_a] = 0;
(d[craf_1]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1_a:
(d[craf_1_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1_a]/dt)/d[craf_1_PKC_a_pool] = 4;
(d[craf_1_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1_a]/dt)/d[craf_1_a_MAPK_a] = --40;
(d[craf_1_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1_a]/dt)/d[craf_1_a_PPhosphatase2A] = --25.0002;
(d[craf_1_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 6;
(d[craf_1_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1_a]/dt)/d[AA] = 0;
(d[craf_1_a]/dt)/d[MAPK_a] = -(1.95 * craf_1_a);
(d[craf_1_a]/dt)/d[MKP_1] = 0;
(d[craf_1_a]/dt)/d[PPhosphatase2A] = -(1.98 * craf_1_a);
(d[craf_1_a]/dt)/d[tot_MKP1] = 0;
(d[craf_1_a]/dt)/d[MKP_2] = 0;
(d[craf_1_a]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1_a]/dt)/d[Grb2] = 0;
(d[craf_1_a]/dt)/d[Sos_Grb2] = 0;
(d[craf_1_a]/dt)/d[Sos_a] = 0;
(d[craf_1_a]/dt)/d[Sos] = 0;
(d[craf_1_a]/dt)/d[PKC_Ca] = 0;
(d[craf_1_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[craf_1_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[craf_1_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[craf_1_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[craf_1_a]/dt)/d[PKC_basal_a] = 0;
(d[craf_1_a]/dt)/d[PKC_AA_a] = 0;
(d[craf_1_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1_a]/dt)/d[PKC_DAG] = 0;
(d[craf_1_a]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1_a]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1_a]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1_a]/dt)/d[craf_1] = 0;
(d[craf_1_a]/dt)/d[craf_1_a] = -(60 * GTP_Ras) - 1.95 * MAPK_a - 1.98 * PPhosphatase2A;
(d[craf_1_a]/dt)/d[MAPKK] = 0;
(d[craf_1_a]/dt)/d[MAPK] = 0;
(d[craf_1_a]/dt)/d[craf_1_a_a] = 0;
(d[craf_1_a]/dt)/d[MAPK_tyr] = 0;
(d[craf_1_a]/dt)/d[MAPKK_a] = 0;
(d[craf_1_a]/dt)/d[MAPKK_ser] = 0;
(d[craf_1_a]/dt)/d[Raf_GTP_Ras_a] = 0.5;
(d[craf_1_a]/dt)/d[RGR] = 0;
(d[craf_1_a]/dt)/d[Ubiquitination] = 0;
(d[craf_1_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1_a]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1_a]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1_a]/dt)/d[MKP1_RNA] = 0;
(d[craf_1_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1_a]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1_a]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1_a]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1_a]/dt)/d[PLA2_a] = 0;
(d[craf_1_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1_a]/dt)/d[inact_GEF] = 0;
(d[craf_1_a]/dt)/d[GEF_a] = 0;
(d[craf_1_a]/dt)/d[GTP_Ras] = -(60 * craf_1_a);
(d[craf_1_a]/dt)/d[GDP_Ras] = 0;
(d[craf_1_a]/dt)/d[GAP_a] = 0;
(d[craf_1_a]/dt)/d[GAP] = 0;
(d[craf_1_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1_a]/dt)/d[PDGFR] = 0;
(d[craf_1_a]/dt)/d[L_PDGFR] = 0;
(d[craf_1_a]/dt)/d[SHC] = 0;
(d[craf_1_a]/dt)/d[SHC_a] = 0;
(d[craf_1_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK:
(d[MAPKK]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPKK]/dt)/d[MAPKK_ser_PPhosphatase2A] = 6;
(d[MAPKK]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK]/dt)/d[AA] = 0;
(d[MAPKK]/dt)/d[MAPK_a] = 0;
(d[MAPKK]/dt)/d[MKP_1] = 0;
(d[MAPKK]/dt)/d[PPhosphatase2A] = 0;
(d[MAPKK]/dt)/d[tot_MKP1] = 0;
(d[MAPKK]/dt)/d[MKP_2] = 0;
(d[MAPKK]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK]/dt)/d[Grb2] = 0;
(d[MAPKK]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK]/dt)/d[Sos_a] = 0;
(d[MAPKK]/dt)/d[Sos] = 0;
(d[MAPKK]/dt)/d[PKC_Ca] = 0;
(d[MAPKK]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK]/dt)/d[PKC_DAG] = 0;
(d[MAPKK]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK]/dt)/d[MAPKK_Raf_GTP_Ras_a] = --0.42;
(d[MAPKK]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPKK]/dt)/d[MAPKK_RGR] = --0.42;
(d[MAPKK]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPKK]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK]/dt)/d[craf_1] = 0;
(d[MAPKK]/dt)/d[craf_1_a] = 0;
(d[MAPKK]/dt)/d[MAPKK] = -(3.3 * Raf_GTP_Ras_a) - 3.3 * RGR;
(d[MAPKK]/dt)/d[MAPK] = 0;
(d[MAPKK]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK]/dt)/d[MAPKK_a] = 0;
(d[MAPKK]/dt)/d[MAPKK_ser] = 0;
(d[MAPKK]/dt)/d[Raf_GTP_Ras_a] = -(3.3 * MAPKK);
(d[MAPKK]/dt)/d[RGR] = -(3.3 * MAPKK);
(d[MAPKK]/dt)/d[Ubiquitination] = 0;
(d[MAPKK]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK]/dt)/d[PLA2_a] = 0;
(d[MAPKK]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK]/dt)/d[inact_GEF] = 0;
(d[MAPKK]/dt)/d[GEF_a] = 0;
(d[MAPKK]/dt)/d[GTP_Ras] = 0;
(d[MAPKK]/dt)/d[GDP_Ras] = 0;
(d[MAPKK]/dt)/d[GAP_a] = 0;
(d[MAPKK]/dt)/d[GAP] = 0;
(d[MAPKK]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK]/dt)/d[PDGFR] = 0;
(d[MAPKK]/dt)/d[L_PDGFR] = 0;
(d[MAPKK]/dt)/d[SHC] = 0;
(d[MAPKK]/dt)/d[SHC_a] = 0;
(d[MAPKK]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK:
(d[MAPK]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK]/dt)/d[MAPK_tyr_MKP_1] = 1;
(d[MAPK]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPK]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK]/dt)/d[MAPK_tyr_MKP_2] = 1;
(d[MAPK]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPK]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK]/dt)/d[AA] = 0;
(d[MAPK]/dt)/d[MAPK_a] = 0;
(d[MAPK]/dt)/d[MKP_1] = 0;
(d[MAPK]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK]/dt)/d[tot_MKP1] = 0;
(d[MAPK]/dt)/d[MKP_2] = 0;
(d[MAPK]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK]/dt)/d[Grb2] = 0;
(d[MAPK]/dt)/d[Sos_Grb2] = 0;
(d[MAPK]/dt)/d[Sos_a] = 0;
(d[MAPK]/dt)/d[Sos] = 0;
(d[MAPK]/dt)/d[PKC_Ca] = 0;
(d[MAPK]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK]/dt)/d[PKC_basal_a] = 0;
(d[MAPK]/dt)/d[PKC_AA_a] = 0;
(d[MAPK]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK]/dt)/d[PKC_DAG] = 0;
(d[MAPK]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK]/dt)/d[MAPK_MAPKK_a] = --0.6;
(d[MAPK]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPK]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK]/dt)/d[MAPK_tyr_MKP_1_a_a] = 1;
(d[MAPK]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPK]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK]/dt)/d[craf_1] = 0;
(d[MAPK]/dt)/d[craf_1_a] = 0;
(d[MAPK]/dt)/d[MAPKK] = 0;
(d[MAPK]/dt)/d[MAPK] = -(16.2 * MAPKK_a);
(d[MAPK]/dt)/d[craf_1_a_a] = 0;
(d[MAPK]/dt)/d[MAPK_tyr] = 0;
(d[MAPK]/dt)/d[MAPKK_a] = -(16.2 * MAPK);
(d[MAPK]/dt)/d[MAPKK_ser] = 0;
(d[MAPK]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK]/dt)/d[RGR] = 0;
(d[MAPK]/dt)/d[Ubiquitination] = 0;
(d[MAPK]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK]/dt)/d[MKP_1_a_a] = 0;
(d[MAPK]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK]/dt)/d[MKP1_RNA] = 0;
(d[MAPK]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK]/dt)/d[PLA2_a] = 0;
(d[MAPK]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK]/dt)/d[inact_GEF] = 0;
(d[MAPK]/dt)/d[GEF_a] = 0;
(d[MAPK]/dt)/d[GTP_Ras] = 0;
(d[MAPK]/dt)/d[GDP_Ras] = 0;
(d[MAPK]/dt)/d[GAP_a] = 0;
(d[MAPK]/dt)/d[GAP] = 0;
(d[MAPK]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK]/dt)/d[PDGFR] = 0;
(d[MAPK]/dt)/d[L_PDGFR] = 0;
(d[MAPK]/dt)/d[SHC] = 0;
(d[MAPK]/dt)/d[SHC_a] = 0;
(d[MAPK]/dt)/d[Internal_L_PDGFR] = 0;
# craf_1_a_a:
(d[craf_1_a_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[craf_1_a_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[craf_1_a_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[craf_1_a_a]/dt)/d[craf_1_a_MAPK_a] = 10;
(d[craf_1_a_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[craf_1_a_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[craf_1_a_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[craf_1_a_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[craf_1_a_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = --25.0002;
(d[craf_1_a_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[craf_1_a_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[craf_1_a_a]/dt)/d[AA] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_a] = 0;
(d[craf_1_a_a]/dt)/d[MKP_1] = 0;
(d[craf_1_a_a]/dt)/d[PPhosphatase2A] = -(1.98 * craf_1_a_a);
(d[craf_1_a_a]/dt)/d[tot_MKP1] = 0;
(d[craf_1_a_a]/dt)/d[MKP_2] = 0;
(d[craf_1_a_a]/dt)/d[Sos_a_Grb2] = 0;
(d[craf_1_a_a]/dt)/d[Grb2] = 0;
(d[craf_1_a_a]/dt)/d[Sos_Grb2] = 0;
(d[craf_1_a_a]/dt)/d[Sos_a] = 0;
(d[craf_1_a_a]/dt)/d[Sos] = 0;
(d[craf_1_a_a]/dt)/d[PKC_Ca] = 0;
(d[craf_1_a_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[craf_1_a_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[craf_1_a_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[craf_1_a_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[craf_1_a_a]/dt)/d[PKC_basal_a] = 0;
(d[craf_1_a_a]/dt)/d[PKC_AA_a] = 0;
(d[craf_1_a_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[craf_1_a_a]/dt)/d[PKC_DAG] = 0;
(d[craf_1_a_a]/dt)/d[PKC_DAG_AA] = 0;
(d[craf_1_a_a]/dt)/d[PKC_cytosolic] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_RGR] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[craf_1_a_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[craf_1_a_a]/dt)/d[craf_1] = 0;
(d[craf_1_a_a]/dt)/d[craf_1_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK] = 0;
(d[craf_1_a_a]/dt)/d[MAPK] = 0;
(d[craf_1_a_a]/dt)/d[craf_1_a_a] = -(1.98 * PPhosphatase2A);
(d[craf_1_a_a]/dt)/d[MAPK_tyr] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_a] = 0;
(d[craf_1_a_a]/dt)/d[MAPKK_ser] = 0;
(d[craf_1_a_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[craf_1_a_a]/dt)/d[RGR] = 0;
(d[craf_1_a_a]/dt)/d[Ubiquitination] = 0;
(d[craf_1_a_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[craf_1_a_a]/dt)/d[MKP_1_a_a] = 0;
(d[craf_1_a_a]/dt)/d[nuc_MAPK_a] = 0;
(d[craf_1_a_a]/dt)/d[MKP1_RNA] = 0;
(d[craf_1_a_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[craf_1_a_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[craf_1_a_a]/dt)/d[PLA2_cytosolic] = 0;
(d[craf_1_a_a]/dt)/d[PLA2_Ca_a] = 0;
(d[craf_1_a_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[PLA2_a_Ca] = 0;
(d[craf_1_a_a]/dt)/d[PLA2_a] = 0;
(d[craf_1_a_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[craf_1_a_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[craf_1_a_a]/dt)/d[inact_GEF] = 0;
(d[craf_1_a_a]/dt)/d[GEF_a] = 0;
(d[craf_1_a_a]/dt)/d[GTP_Ras] = 0;
(d[craf_1_a_a]/dt)/d[GDP_Ras] = 0;
(d[craf_1_a_a]/dt)/d[GAP_a] = 0;
(d[craf_1_a_a]/dt)/d[GAP] = 0;
(d[craf_1_a_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[craf_1_a_a]/dt)/d[PDGFR] = 0;
(d[craf_1_a_a]/dt)/d[L_PDGFR] = 0;
(d[craf_1_a_a]/dt)/d[SHC] = 0;
(d[craf_1_a_a]/dt)/d[SHC_a] = 0;
(d[craf_1_a_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPK_tyr:
(d[MAPK_tyr]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPK_tyr]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPK_tyr]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPK_tyr]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[MAPK_tyr_MKP_1] = 4;
(d[MAPK_tyr]/dt)/d[MAPK_a_MKP_1] = 1;
(d[MAPK_tyr]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPK_tyr]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MAPK_tyr]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPK_tyr]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPK_tyr]/dt)/d[MAPK_tyr_MKP_2] = --4;
(d[MAPK_tyr]/dt)/d[MAPK_a_MKP_2] = 1;
(d[MAPK_tyr]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPK_tyr]/dt)/d[AA] = 0;
(d[MAPK_tyr]/dt)/d[MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[MKP_1] = -(74.999 * MAPK_tyr);
(d[MAPK_tyr]/dt)/d[PPhosphatase2A] = 0;
(d[MAPK_tyr]/dt)/d[tot_MKP1] = 0;
(d[MAPK_tyr]/dt)/d[MKP_2] = -(74.999 * MAPK_tyr);
(d[MAPK_tyr]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPK_tyr]/dt)/d[Grb2] = 0;
(d[MAPK_tyr]/dt)/d[Sos_Grb2] = 0;
(d[MAPK_tyr]/dt)/d[Sos_a] = 0;
(d[MAPK_tyr]/dt)/d[Sos] = 0;
(d[MAPK_tyr]/dt)/d[PKC_Ca] = 0;
(d[MAPK_tyr]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPK_tyr]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPK_tyr]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPK_tyr]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPK_tyr]/dt)/d[PKC_basal_a] = 0;
(d[MAPK_tyr]/dt)/d[PKC_AA_a] = 0;
(d[MAPK_tyr]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPK_tyr]/dt)/d[PKC_DAG] = 0;
(d[MAPK_tyr]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPK_tyr]/dt)/d[PKC_cytosolic] = 0;
(d[MAPK_tyr]/dt)/d[MAPK_MAPKK_a] = 0.15;
(d[MAPK_tyr]/dt)/d[MAPK_tyr_MAPKK_a] = --0.6;
(d[MAPK_tyr]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr]/dt)/d[MAPKK_RGR] = 0;
(d[MAPK_tyr]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MAPK_tyr]/dt)/d[MAPK_tyr_MKP_1_a_a] = --4;
(d[MAPK_tyr]/dt)/d[MAPK_a_MKP_1_a_a] = 1;
(d[MAPK_tyr]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[craf_1] = 0;
(d[MAPK_tyr]/dt)/d[craf_1_a] = 0;
(d[MAPK_tyr]/dt)/d[MAPKK] = 0;
(d[MAPK_tyr]/dt)/d[MAPK] = 0;
(d[MAPK_tyr]/dt)/d[craf_1_a_a] = 0;
(d[MAPK_tyr]/dt)/d[MAPK_tyr] = -(74.999 * MKP_1) - 74.999 * MKP_2 - 16.2 * MAPKK_a - 74.999 * MKP_1_a_a;
(d[MAPK_tyr]/dt)/d[MAPKK_a] = -(16.2 * MAPK_tyr);
(d[MAPK_tyr]/dt)/d[MAPKK_ser] = 0;
(d[MAPK_tyr]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPK_tyr]/dt)/d[RGR] = 0;
(d[MAPK_tyr]/dt)/d[Ubiquitination] = 0;
(d[MAPK_tyr]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPK_tyr]/dt)/d[MKP_1_a_a] = -(74.999 * MAPK_tyr);
(d[MAPK_tyr]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPK_tyr]/dt)/d[MKP1_RNA] = 0;
(d[MAPK_tyr]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPK_tyr]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPK_tyr]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPK_tyr]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPK_tyr]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPK_tyr]/dt)/d[PLA2_a] = 0;
(d[MAPK_tyr]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPK_tyr]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPK_tyr]/dt)/d[inact_GEF] = 0;
(d[MAPK_tyr]/dt)/d[GEF_a] = 0;
(d[MAPK_tyr]/dt)/d[GTP_Ras] = 0;
(d[MAPK_tyr]/dt)/d[GDP_Ras] = 0;
(d[MAPK_tyr]/dt)/d[GAP_a] = 0;
(d[MAPK_tyr]/dt)/d[GAP] = 0;
(d[MAPK_tyr]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPK_tyr]/dt)/d[PDGFR] = 0;
(d[MAPK_tyr]/dt)/d[L_PDGFR] = 0;
(d[MAPK_tyr]/dt)/d[SHC] = 0;
(d[MAPK_tyr]/dt)/d[SHC_a] = 0;
(d[MAPK_tyr]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_a:
(d[MAPKK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 25.0002;
(d[MAPKK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MAPKK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_a]/dt)/d[AA] = 0;
(d[MAPKK_a]/dt)/d[MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[MKP_1] = 0;
(d[MAPKK_a]/dt)/d[PPhosphatase2A] = -(1.98 * MAPKK_a);
(d[MAPKK_a]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_a]/dt)/d[MKP_2] = 0;
(d[MAPKK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_a]/dt)/d[Grb2] = 0;
(d[MAPKK_a]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_a]/dt)/d[Sos_a] = 0;
(d[MAPKK_a]/dt)/d[Sos] = 0;
(d[MAPKK_a]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_a]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_a]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_a]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_a]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_a]/dt)/d[MAPK_MAPKK_a] = --0.6 + 0.15;
(d[MAPKK_a]/dt)/d[MAPK_tyr_MAPKK_a] = --0.6 + 0.15;
(d[MAPKK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MAPKK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0.105;
(d[MAPKK_a]/dt)/d[MAPKK_RGR] = 0;
(d[MAPKK_a]/dt)/d[MAPKK_ser_RGR] = 0.105;
(d[MAPKK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[craf_1] = 0;
(d[MAPKK_a]/dt)/d[craf_1_a] = 0;
(d[MAPKK_a]/dt)/d[MAPKK] = 0;
(d[MAPKK_a]/dt)/d[MAPK] = -(16.2 * MAPKK_a);
(d[MAPKK_a]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_a]/dt)/d[MAPK_tyr] = -(16.2 * MAPKK_a);
(d[MAPKK_a]/dt)/d[MAPKK_a] = -(1.98 * PPhosphatase2A) - 16.2 * MAPK - 16.2 * MAPK_tyr;
(d[MAPKK_a]/dt)/d[MAPKK_ser] = 0;
(d[MAPKK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MAPKK_a]/dt)/d[RGR] = 0;
(d[MAPKK_a]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_a]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_a]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_a]/dt)/d[PLA2_a] = 0;
(d[MAPKK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_a]/dt)/d[inact_GEF] = 0;
(d[MAPKK_a]/dt)/d[GEF_a] = 0;
(d[MAPKK_a]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_a]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_a]/dt)/d[GAP_a] = 0;
(d[MAPKK_a]/dt)/d[GAP] = 0;
(d[MAPKK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_a]/dt)/d[PDGFR] = 0;
(d[MAPKK_a]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_a]/dt)/d[SHC] = 0;
(d[MAPKK_a]/dt)/d[SHC_a] = 0;
(d[MAPKK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MAPKK_ser:
(d[MAPKK_ser]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MAPKK_ser]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MAPKK_ser]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MAPKK_ser]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MAPKK_ser]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MAPKK_ser]/dt)/d[MAPKK_a_PPhosphatase2A] = 6;
(d[MAPKK_ser]/dt)/d[MAPKK_ser_PPhosphatase2A] = --25.0002;
(d[MAPKK_ser]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MAPKK_ser]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MAPKK_ser]/dt)/d[AA] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[MKP_1] = 0;
(d[MAPKK_ser]/dt)/d[PPhosphatase2A] = -(1.98 * MAPKK_ser);
(d[MAPKK_ser]/dt)/d[tot_MKP1] = 0;
(d[MAPKK_ser]/dt)/d[MKP_2] = 0;
(d[MAPKK_ser]/dt)/d[Sos_a_Grb2] = 0;
(d[MAPKK_ser]/dt)/d[Grb2] = 0;
(d[MAPKK_ser]/dt)/d[Sos_Grb2] = 0;
(d[MAPKK_ser]/dt)/d[Sos_a] = 0;
(d[MAPKK_ser]/dt)/d[Sos] = 0;
(d[MAPKK_ser]/dt)/d[PKC_Ca] = 0;
(d[MAPKK_ser]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MAPKK_ser]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MAPKK_ser]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MAPKK_ser]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MAPKK_ser]/dt)/d[PKC_basal_a] = 0;
(d[MAPKK_ser]/dt)/d[PKC_AA_a] = 0;
(d[MAPKK_ser]/dt)/d[PKC_Ca_DAG] = 0;
(d[MAPKK_ser]/dt)/d[PKC_DAG] = 0;
(d[MAPKK_ser]/dt)/d[PKC_DAG_AA] = 0;
(d[MAPKK_ser]/dt)/d[PKC_cytosolic] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0.105;
(d[MAPKK_ser]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = --0.42;
(d[MAPKK_ser]/dt)/d[MAPKK_RGR] = 0.105;
(d[MAPKK_ser]/dt)/d[MAPKK_ser_RGR] = --0.42;
(d[MAPKK_ser]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MAPKK_ser]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[craf_1] = 0;
(d[MAPKK_ser]/dt)/d[craf_1_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPKK] = 0;
(d[MAPKK_ser]/dt)/d[MAPK] = 0;
(d[MAPKK_ser]/dt)/d[craf_1_a_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPK_tyr] = 0;
(d[MAPKK_ser]/dt)/d[MAPKK_a] = 0;
(d[MAPKK_ser]/dt)/d[MAPKK_ser] = -(1.98 * PPhosphatase2A) - 3.3 * Raf_GTP_Ras_a - 3.3 * RGR;
(d[MAPKK_ser]/dt)/d[Raf_GTP_Ras_a] = -(3.3 * MAPKK_ser);
(d[MAPKK_ser]/dt)/d[RGR] = -(3.3 * MAPKK_ser);
(d[MAPKK_ser]/dt)/d[Ubiquitination] = 0;
(d[MAPKK_ser]/dt)/d[MKP_1_ser359_a] = 0;
(d[MAPKK_ser]/dt)/d[MKP_1_a_a] = 0;
(d[MAPKK_ser]/dt)/d[nuc_MAPK_a] = 0;
(d[MAPKK_ser]/dt)/d[MKP1_RNA] = 0;
(d[MAPKK_ser]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MAPKK_ser]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MAPKK_ser]/dt)/d[PLA2_cytosolic] = 0;
(d[MAPKK_ser]/dt)/d[PLA2_Ca_a] = 0;
(d[MAPKK_ser]/dt)/d[PIP2_PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[PLA2_a_Ca] = 0;
(d[MAPKK_ser]/dt)/d[PLA2_a] = 0;
(d[MAPKK_ser]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MAPKK_ser]/dt)/d[GTP_Ras_GAP] = 0;
(d[MAPKK_ser]/dt)/d[inact_GEF] = 0;
(d[MAPKK_ser]/dt)/d[GEF_a] = 0;
(d[MAPKK_ser]/dt)/d[GTP_Ras] = 0;
(d[MAPKK_ser]/dt)/d[GDP_Ras] = 0;
(d[MAPKK_ser]/dt)/d[GAP_a] = 0;
(d[MAPKK_ser]/dt)/d[GAP] = 0;
(d[MAPKK_ser]/dt)/d[SHC_L_PDGFR] = 0;
(d[MAPKK_ser]/dt)/d[PDGFR] = 0;
(d[MAPKK_ser]/dt)/d[L_PDGFR] = 0;
(d[MAPKK_ser]/dt)/d[SHC] = 0;
(d[MAPKK_ser]/dt)/d[SHC_a] = 0;
(d[MAPKK_ser]/dt)/d[Internal_L_PDGFR] = 0;
# Raf_GTP_Ras_a:
(d[Raf_GTP_Ras_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[AA] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP_1] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PPhosphatase2A] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[tot_MKP1] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP_2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Sos_a_Grb2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Grb2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Sos_Grb2] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Sos_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Sos] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_Ca] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_basal_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_AA_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_DAG] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_DAG_AA] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PKC_cytosolic] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = --0.42 + 0.105;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = --0.42 + 0.105;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_RGR] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1_a] = 60 * GTP_Ras;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK] = -(3.3 * Raf_GTP_Ras_a);
(d[Raf_GTP_Ras_a]/dt)/d[MAPK] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[craf_1_a_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPK_tyr] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MAPKK_ser] = -(3.3 * Raf_GTP_Ras_a);
(d[Raf_GTP_Ras_a]/dt)/d[Raf_GTP_Ras_a] = -0.5 - 3.3 * MAPKK - 3.3 * MAPKK_ser;
(d[Raf_GTP_Ras_a]/dt)/d[RGR] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Ubiquitination] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP_1_a_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[nuc_MAPK_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[MKP1_RNA] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PLA2_cytosolic] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PLA2_Ca_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PLA2_a_Ca] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PLA2_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[inact_GEF] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GEF_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GTP_Ras] = 60 * craf_1_a;
(d[Raf_GTP_Ras_a]/dt)/d[GDP_Ras] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GAP_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[GAP] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[PDGFR] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[L_PDGFR] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[SHC] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[SHC_a] = 0;
(d[Raf_GTP_Ras_a]/dt)/d[Internal_L_PDGFR] = 0;
# RGR:
(d[RGR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[RGR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[RGR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[RGR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[RGR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[RGR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[RGR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[RGR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[RGR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[RGR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[RGR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[RGR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[RGR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[RGR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[RGR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[RGR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[RGR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[RGR]/dt)/d[AA] = 0;
(d[RGR]/dt)/d[MAPK_a] = 0;
(d[RGR]/dt)/d[MKP_1] = 0;
(d[RGR]/dt)/d[PPhosphatase2A] = 0;
(d[RGR]/dt)/d[tot_MKP1] = 0;
(d[RGR]/dt)/d[MKP_2] = 0;
(d[RGR]/dt)/d[Sos_a_Grb2] = 0;
(d[RGR]/dt)/d[Grb2] = 0;
(d[RGR]/dt)/d[Sos_Grb2] = 0;
(d[RGR]/dt)/d[Sos_a] = 0;
(d[RGR]/dt)/d[Sos] = 0;
(d[RGR]/dt)/d[PKC_Ca] = 0;
(d[RGR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[RGR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[RGR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[RGR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[RGR]/dt)/d[PKC_basal_a] = 0;
(d[RGR]/dt)/d[PKC_AA_a] = 0;
(d[RGR]/dt)/d[PKC_Ca_DAG] = 0;
(d[RGR]/dt)/d[PKC_DAG] = 0;
(d[RGR]/dt)/d[PKC_DAG_AA] = 0;
(d[RGR]/dt)/d[PKC_cytosolic] = 0;
(d[RGR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[RGR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[RGR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[RGR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[RGR]/dt)/d[MAPKK_RGR] = --0.42 + 0.105;
(d[RGR]/dt)/d[MAPKK_ser_RGR] = --0.42 + 0.105;
(d[RGR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[RGR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[RGR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[RGR]/dt)/d[craf_1] = 6 * GTP_Ras;
(d[RGR]/dt)/d[craf_1_a] = 0;
(d[RGR]/dt)/d[MAPKK] = -(3.3 * RGR);
(d[RGR]/dt)/d[MAPK] = 0;
(d[RGR]/dt)/d[craf_1_a_a] = 0;
(d[RGR]/dt)/d[MAPK_tyr] = 0;
(d[RGR]/dt)/d[MAPKK_a] = 0;
(d[RGR]/dt)/d[MAPKK_ser] = -(3.3 * RGR);
(d[RGR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[RGR]/dt)/d[RGR] = -1 - 3.3 * MAPKK - 3.3 * MAPKK_ser;
(d[RGR]/dt)/d[Ubiquitination] = 0;
(d[RGR]/dt)/d[MKP_1_ser359_a] = 0;
(d[RGR]/dt)/d[MKP_1_a_a] = 0;
(d[RGR]/dt)/d[nuc_MAPK_a] = 0;
(d[RGR]/dt)/d[MKP1_RNA] = 0;
(d[RGR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[RGR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[RGR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[RGR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[RGR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[RGR]/dt)/d[PLA2_cytosolic] = 0;
(d[RGR]/dt)/d[PLA2_Ca_a] = 0;
(d[RGR]/dt)/d[PIP2_PLA2_a] = 0;
(d[RGR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[RGR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[RGR]/dt)/d[PLA2_a_Ca] = 0;
(d[RGR]/dt)/d[PLA2_a] = 0;
(d[RGR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[RGR]/dt)/d[GTP_Ras_GAP] = 0;
(d[RGR]/dt)/d[inact_GEF] = 0;
(d[RGR]/dt)/d[GEF_a] = 0;
(d[RGR]/dt)/d[GTP_Ras] = 6 * craf_1;
(d[RGR]/dt)/d[GDP_Ras] = 0;
(d[RGR]/dt)/d[GAP_a] = 0;
(d[RGR]/dt)/d[GAP] = 0;
(d[RGR]/dt)/d[SHC_L_PDGFR] = 0;
(d[RGR]/dt)/d[PDGFR] = 0;
(d[RGR]/dt)/d[L_PDGFR] = 0;
(d[RGR]/dt)/d[SHC] = 0;
(d[RGR]/dt)/d[SHC_a] = 0;
(d[RGR]/dt)/d[Internal_L_PDGFR] = 0;
# Ubiquitination:
(d[Ubiquitination]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Ubiquitination]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Ubiquitination]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Ubiquitination]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Ubiquitination]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Ubiquitination]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Ubiquitination]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Ubiquitination]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Ubiquitination]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Ubiquitination]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Ubiquitination]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Ubiquitination]/dt)/d[AA] = 0;
(d[Ubiquitination]/dt)/d[MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[MKP_1] = 0.00037;
(d[Ubiquitination]/dt)/d[PPhosphatase2A] = 0;
(d[Ubiquitination]/dt)/d[tot_MKP1] = 0;
(d[Ubiquitination]/dt)/d[MKP_2] = 0;
(d[Ubiquitination]/dt)/d[Sos_a_Grb2] = 0;
(d[Ubiquitination]/dt)/d[Grb2] = 0;
(d[Ubiquitination]/dt)/d[Sos_Grb2] = 0;
(d[Ubiquitination]/dt)/d[Sos_a] = 0;
(d[Ubiquitination]/dt)/d[Sos] = 0;
(d[Ubiquitination]/dt)/d[PKC_Ca] = 0;
(d[Ubiquitination]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Ubiquitination]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Ubiquitination]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Ubiquitination]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Ubiquitination]/dt)/d[PKC_basal_a] = 0;
(d[Ubiquitination]/dt)/d[PKC_AA_a] = 0;
(d[Ubiquitination]/dt)/d[PKC_Ca_DAG] = 0;
(d[Ubiquitination]/dt)/d[PKC_DAG] = 0;
(d[Ubiquitination]/dt)/d[PKC_DAG_AA] = 0;
(d[Ubiquitination]/dt)/d[PKC_cytosolic] = 0;
(d[Ubiquitination]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Ubiquitination]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_RGR] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Ubiquitination]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Ubiquitination]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Ubiquitination]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[craf_1] = 0;
(d[Ubiquitination]/dt)/d[craf_1_a] = 0;
(d[Ubiquitination]/dt)/d[MAPKK] = 0;
(d[Ubiquitination]/dt)/d[MAPK] = 0;
(d[Ubiquitination]/dt)/d[craf_1_a_a] = 0;
(d[Ubiquitination]/dt)/d[MAPK_tyr] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_a] = 0;
(d[Ubiquitination]/dt)/d[MAPKK_ser] = 0;
(d[Ubiquitination]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Ubiquitination]/dt)/d[RGR] = 0;
(d[Ubiquitination]/dt)/d[Ubiquitination] = 0;
(d[Ubiquitination]/dt)/d[MKP_1_ser359_a] = 0.0001;
(d[Ubiquitination]/dt)/d[MKP_1_a_a] = 0.0001;
(d[Ubiquitination]/dt)/d[nuc_MAPK_a] = 0;
(d[Ubiquitination]/dt)/d[MKP1_RNA] = 0;
(d[Ubiquitination]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Ubiquitination]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Ubiquitination]/dt)/d[PLA2_cytosolic] = 0;
(d[Ubiquitination]/dt)/d[PLA2_Ca_a] = 0;
(d[Ubiquitination]/dt)/d[PIP2_PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[PLA2_a_Ca] = 0;
(d[Ubiquitination]/dt)/d[PLA2_a] = 0;
(d[Ubiquitination]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Ubiquitination]/dt)/d[GTP_Ras_GAP] = 0;
(d[Ubiquitination]/dt)/d[inact_GEF] = 0;
(d[Ubiquitination]/dt)/d[GEF_a] = 0;
(d[Ubiquitination]/dt)/d[GTP_Ras] = 0;
(d[Ubiquitination]/dt)/d[GDP_Ras] = 0;
(d[Ubiquitination]/dt)/d[GAP_a] = 0;
(d[Ubiquitination]/dt)/d[GAP] = 0;
(d[Ubiquitination]/dt)/d[SHC_L_PDGFR] = 0;
(d[Ubiquitination]/dt)/d[PDGFR] = 0;
(d[Ubiquitination]/dt)/d[L_PDGFR] = 0;
(d[Ubiquitination]/dt)/d[SHC] = 0;
(d[Ubiquitination]/dt)/d[SHC_a] = 0;
(d[Ubiquitination]/dt)/d[Internal_L_PDGFR] = 0;
# MKP_1_ser359_a:
(d[MKP_1_ser359_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP_1_ser359_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP_1_ser359_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MKP_1_MAPK_a] = 1;
(d[MKP_1_ser359_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = --4;
(d[MKP_1_ser359_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MKP_1_ser359_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP_1_ser359_a]/dt)/d[AA] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_a] = -(0.195 * MKP_1_ser359_a);
(d[MKP_1_ser359_a]/dt)/d[MKP_1] = 0;
(d[MKP_1_ser359_a]/dt)/d[PPhosphatase2A] = 0;
(d[MKP_1_ser359_a]/dt)/d[tot_MKP1] = 0;
(d[MKP_1_ser359_a]/dt)/d[MKP_2] = 0;
(d[MKP_1_ser359_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP_1_ser359_a]/dt)/d[Grb2] = 0;
(d[MKP_1_ser359_a]/dt)/d[Sos_Grb2] = 0;
(d[MKP_1_ser359_a]/dt)/d[Sos_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[Sos] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_Ca] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_basal_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_AA_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_DAG] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP_1_ser359_a]/dt)/d[PKC_cytosolic] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_RGR] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK] = 0;
(d[MKP_1_ser359_a]/dt)/d[craf_1_a_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPK_tyr] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MAPKK_ser] = 0;
(d[MKP_1_ser359_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[RGR] = 0;
(d[MKP_1_ser359_a]/dt)/d[Ubiquitination] = 0;
(d[MKP_1_ser359_a]/dt)/d[MKP_1_ser359_a] = -(0.195 * MAPK_a) - 0.0001 - 0.0001;
(d[MKP_1_ser359_a]/dt)/d[MKP_1_a_a] = 0.0001;
(d[MKP_1_ser359_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[MKP1_RNA] = 0;
(d[MKP_1_ser359_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP_1_ser359_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP_1_ser359_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP_1_ser359_a]/dt)/d[PLA2_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP_1_ser359_a]/dt)/d[inact_GEF] = 0;
(d[MKP_1_ser359_a]/dt)/d[GEF_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[GTP_Ras] = 0;
(d[MKP_1_ser359_a]/dt)/d[GDP_Ras] = 0;
(d[MKP_1_ser359_a]/dt)/d[GAP_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[GAP] = 0;
(d[MKP_1_ser359_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP_1_ser359_a]/dt)/d[PDGFR] = 0;
(d[MKP_1_ser359_a]/dt)/d[L_PDGFR] = 0;
(d[MKP_1_ser359_a]/dt)/d[SHC] = 0;
(d[MKP_1_ser359_a]/dt)/d[SHC_a] = 0;
(d[MKP_1_ser359_a]/dt)/d[Internal_L_PDGFR] = 0;
# MKP_1_a_a:
(d[MKP_1_a_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP_1_a_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP_1_a_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP_1_a_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP_1_a_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MKP_1_a_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 1;
(d[MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MKP_1_a_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP_1_a_a]/dt)/d[AA] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_a] = -(74.999 * MKP_1_a_a);
(d[MKP_1_a_a]/dt)/d[MKP_1] = 0;
(d[MKP_1_a_a]/dt)/d[PPhosphatase2A] = 0;
(d[MKP_1_a_a]/dt)/d[tot_MKP1] = 0;
(d[MKP_1_a_a]/dt)/d[MKP_2] = 0;
(d[MKP_1_a_a]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP_1_a_a]/dt)/d[Grb2] = 0;
(d[MKP_1_a_a]/dt)/d[Sos_Grb2] = 0;
(d[MKP_1_a_a]/dt)/d[Sos_a] = 0;
(d[MKP_1_a_a]/dt)/d[Sos] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_Ca] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_basal_a] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_AA_a] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_DAG] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP_1_a_a]/dt)/d[PKC_cytosolic] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_RGR] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = --4 + 1;
(d[MKP_1_a_a]/dt)/d[MAPK_a_MKP_1_a_a] = --4 + 1;
(d[MKP_1_a_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK] = 0;
(d[MKP_1_a_a]/dt)/d[craf_1_a_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPK_tyr] = -(74.999 * MKP_1_a_a);
(d[MKP_1_a_a]/dt)/d[MAPKK_a] = 0;
(d[MKP_1_a_a]/dt)/d[MAPKK_ser] = 0;
(d[MKP_1_a_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP_1_a_a]/dt)/d[RGR] = 0;
(d[MKP_1_a_a]/dt)/d[Ubiquitination] = 0;
(d[MKP_1_a_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[MKP_1_a_a]/dt)/d[MKP_1_a_a] = -0.0001 - 0.0001 - 74.999 * MAPK_tyr - 74.999 * MAPK_a;
(d[MKP_1_a_a]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP_1_a_a]/dt)/d[MKP1_RNA] = 0;
(d[MKP_1_a_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP_1_a_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP_1_a_a]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP_1_a_a]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP_1_a_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP_1_a_a]/dt)/d[PLA2_a] = 0;
(d[MKP_1_a_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP_1_a_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP_1_a_a]/dt)/d[inact_GEF] = 0;
(d[MKP_1_a_a]/dt)/d[GEF_a] = 0;
(d[MKP_1_a_a]/dt)/d[GTP_Ras] = 0;
(d[MKP_1_a_a]/dt)/d[GDP_Ras] = 0;
(d[MKP_1_a_a]/dt)/d[GAP_a] = 0;
(d[MKP_1_a_a]/dt)/d[GAP] = 0;
(d[MKP_1_a_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP_1_a_a]/dt)/d[PDGFR] = 0;
(d[MKP_1_a_a]/dt)/d[L_PDGFR] = 0;
(d[MKP_1_a_a]/dt)/d[SHC] = 0;
(d[MKP_1_a_a]/dt)/d[SHC_a] = 0;
(d[MKP_1_a_a]/dt)/d[Internal_L_PDGFR] = 0;
# nuc_MAPK_a:
(d[nuc_MAPK_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[nuc_MAPK_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[nuc_MAPK_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[nuc_MAPK_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[nuc_MAPK_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[nuc_MAPK_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[nuc_MAPK_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[nuc_MAPK_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[nuc_MAPK_a]/dt)/d[AA] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_a] = 0.01 * 2 * MAPK_a;
(d[nuc_MAPK_a]/dt)/d[MKP_1] = 0;
(d[nuc_MAPK_a]/dt)/d[PPhosphatase2A] = 0;
(d[nuc_MAPK_a]/dt)/d[tot_MKP1] = 0;
(d[nuc_MAPK_a]/dt)/d[MKP_2] = 0;
(d[nuc_MAPK_a]/dt)/d[Sos_a_Grb2] = 0;
(d[nuc_MAPK_a]/dt)/d[Grb2] = 0;
(d[nuc_MAPK_a]/dt)/d[Sos_Grb2] = 0;
(d[nuc_MAPK_a]/dt)/d[Sos_a] = 0;
(d[nuc_MAPK_a]/dt)/d[Sos] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_Ca] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_basal_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_AA_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_DAG] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_DAG_AA] = 0;
(d[nuc_MAPK_a]/dt)/d[PKC_cytosolic] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_RGR] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[nuc_MAPK_a]/dt)/d[Nucleotides_nuc_MAPK_a] = --0.0032 + 0.0008;
(d[nuc_MAPK_a]/dt)/d[craf_1] = 0;
(d[nuc_MAPK_a]/dt)/d[craf_1_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK] = 0;
(d[nuc_MAPK_a]/dt)/d[craf_1_a_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPK_tyr] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MAPKK_ser] = 0;
(d[nuc_MAPK_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[nuc_MAPK_a]/dt)/d[RGR] = 0;
(d[nuc_MAPK_a]/dt)/d[Ubiquitination] = 0;
(d[nuc_MAPK_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[nuc_MAPK_a]/dt)/d[MKP_1_a_a] = 0;
(d[nuc_MAPK_a]/dt)/d[nuc_MAPK_a] = -0.005 - 0.0001;
(d[nuc_MAPK_a]/dt)/d[MKP1_RNA] = 0;
(d[nuc_MAPK_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[nuc_MAPK_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[nuc_MAPK_a]/dt)/d[PLA2_cytosolic] = 0;
(d[nuc_MAPK_a]/dt)/d[PLA2_Ca_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[PLA2_a_Ca] = 0;
(d[nuc_MAPK_a]/dt)/d[PLA2_a] = 0;
(d[nuc_MAPK_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[nuc_MAPK_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[nuc_MAPK_a]/dt)/d[inact_GEF] = 0;
(d[nuc_MAPK_a]/dt)/d[GEF_a] = 0;
(d[nuc_MAPK_a]/dt)/d[GTP_Ras] = 0;
(d[nuc_MAPK_a]/dt)/d[GDP_Ras] = 0;
(d[nuc_MAPK_a]/dt)/d[GAP_a] = 0;
(d[nuc_MAPK_a]/dt)/d[GAP] = 0;
(d[nuc_MAPK_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[nuc_MAPK_a]/dt)/d[PDGFR] = 0;
(d[nuc_MAPK_a]/dt)/d[L_PDGFR] = 0;
(d[nuc_MAPK_a]/dt)/d[SHC] = 0;
(d[nuc_MAPK_a]/dt)/d[SHC_a] = 0;
(d[nuc_MAPK_a]/dt)/d[Internal_L_PDGFR] = 0;
# MKP1_RNA:
(d[MKP1_RNA]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[MKP1_RNA]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[MKP1_RNA]/dt)/d[GAP_PKC_a_pool] = 0;
(d[MKP1_RNA]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[MKP1_RNA]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[MKP1_RNA]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[MKP1_RNA]/dt)/d[MKP_1_MAPK_a] = 0;
(d[MKP1_RNA]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_a_MKP_1] = 0;
(d[MKP1_RNA]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[MKP1_RNA]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_a_MKP_2] = 0;
(d[MKP1_RNA]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[MKP1_RNA]/dt)/d[AA] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_a] = 0;
(d[MKP1_RNA]/dt)/d[MKP_1] = 0;
(d[MKP1_RNA]/dt)/d[PPhosphatase2A] = 0;
(d[MKP1_RNA]/dt)/d[tot_MKP1] = 0;
(d[MKP1_RNA]/dt)/d[MKP_2] = 0;
(d[MKP1_RNA]/dt)/d[Sos_a_Grb2] = 0;
(d[MKP1_RNA]/dt)/d[Grb2] = 0;
(d[MKP1_RNA]/dt)/d[Sos_Grb2] = 0;
(d[MKP1_RNA]/dt)/d[Sos_a] = 0;
(d[MKP1_RNA]/dt)/d[Sos] = 0;
(d[MKP1_RNA]/dt)/d[PKC_Ca] = 0;
(d[MKP1_RNA]/dt)/d[PKC_DAG_AA_a] = 0;
(d[MKP1_RNA]/dt)/d[PKC_Ca_AA_a] = 0;
(d[MKP1_RNA]/dt)/d[PKC_Ca_memb_a] = 0;
(d[MKP1_RNA]/dt)/d[PKC_DAG_memb_a] = 0;
(d[MKP1_RNA]/dt)/d[PKC_basal_a] = 0;
(d[MKP1_RNA]/dt)/d[PKC_AA_a] = 0;
(d[MKP1_RNA]/dt)/d[PKC_Ca_DAG] = 0;
(d[MKP1_RNA]/dt)/d[PKC_DAG] = 0;
(d[MKP1_RNA]/dt)/d[PKC_DAG_AA] = 0;
(d[MKP1_RNA]/dt)/d[PKC_cytosolic] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_MAPKK_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_RGR] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_ser_RGR] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[MKP1_RNA]/dt)/d[Nucleotides_nuc_MAPK_a] = 0.0008;
(d[MKP1_RNA]/dt)/d[craf_1] = 0;
(d[MKP1_RNA]/dt)/d[craf_1_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK] = 0;
(d[MKP1_RNA]/dt)/d[MAPK] = 0;
(d[MKP1_RNA]/dt)/d[craf_1_a_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPK_tyr] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_a] = 0;
(d[MKP1_RNA]/dt)/d[MAPKK_ser] = 0;
(d[MKP1_RNA]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[MKP1_RNA]/dt)/d[RGR] = 0;
(d[MKP1_RNA]/dt)/d[Ubiquitination] = 0;
(d[MKP1_RNA]/dt)/d[MKP_1_ser359_a] = 0;
(d[MKP1_RNA]/dt)/d[MKP_1_a_a] = 0;
(d[MKP1_RNA]/dt)/d[nuc_MAPK_a] = 0;
(d[MKP1_RNA]/dt)/d[MKP1_RNA] = -0.002;
(d[MKP1_RNA]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[MKP1_RNA]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[MKP1_RNA]/dt)/d[PLA2_cytosolic] = 0;
(d[MKP1_RNA]/dt)/d[PLA2_Ca_a] = 0;
(d[MKP1_RNA]/dt)/d[PIP2_PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[PLA2_a_Ca] = 0;
(d[MKP1_RNA]/dt)/d[PLA2_a] = 0;
(d[MKP1_RNA]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[MKP1_RNA]/dt)/d[GTP_Ras_GAP] = 0;
(d[MKP1_RNA]/dt)/d[inact_GEF] = 0;
(d[MKP1_RNA]/dt)/d[GEF_a] = 0;
(d[MKP1_RNA]/dt)/d[GTP_Ras] = 0;
(d[MKP1_RNA]/dt)/d[GDP_Ras] = 0;
(d[MKP1_RNA]/dt)/d[GAP_a] = 0;
(d[MKP1_RNA]/dt)/d[GAP] = 0;
(d[MKP1_RNA]/dt)/d[SHC_L_PDGFR] = 0;
(d[MKP1_RNA]/dt)/d[PDGFR] = 0;
(d[MKP1_RNA]/dt)/d[L_PDGFR] = 0;
(d[MKP1_RNA]/dt)/d[SHC] = 0;
(d[MKP1_RNA]/dt)/d[SHC_a] = 0;
(d[MKP1_RNA]/dt)/d[Internal_L_PDGFR] = 0;
# APC_PLA2_Ca_a:
(d[APC_PLA2_Ca_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[AA] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP_1] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PPhosphatase2A] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[tot_MKP1] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP_2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Sos_a_Grb2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Grb2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Sos_Grb2] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Sos_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Sos] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_Ca] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_basal_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_AA_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_DAG] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_DAG_AA] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PKC_cytosolic] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_RGR] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[craf_1_a_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPK_tyr] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MAPKK_ser] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[RGR] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Ubiquitination] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP_1_a_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[nuc_MAPK_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[MKP1_RNA] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[APC_PLA2_Ca_a] = -21.6 - 5.4;
(d[APC_PLA2_Ca_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PLA2_cytosolic] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PLA2_Ca_a] = 40.5;
(d[APC_PLA2_Ca_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PLA2_a_Ca] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PLA2_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[inact_GEF] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GEF_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GTP_Ras] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GDP_Ras] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GAP_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[GAP] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[PDGFR] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[L_PDGFR] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[SHC] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[SHC_a] = 0;
(d[APC_PLA2_Ca_a]/dt)/d[Internal_L_PDGFR] = 0;
# APC_PIP2_PLA2_a:
(d[APC_PIP2_PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[AA] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP_1] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP_2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Grb2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Sos_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Sos] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[RGR] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = -44.16 - 11.04;
(d[APC_PIP2_PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PLA2_cytosolic] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PLA2_Ca_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PIP2_PLA2_a] = 82.8;
(d[APC_PIP2_PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PLA2_a_Ca] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PLA2_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[inact_GEF] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GEF_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GAP_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[GAP] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[PDGFR] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[SHC] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[SHC_a] = 0;
(d[APC_PIP2_PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# APC_PIP2_Ca_PLA2_a:
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[AA] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP_1] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP_2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Grb2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Sos_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Sos] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[RGR] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = -144 - 36;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PLA2_cytosolic] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PLA2_Ca_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = 270;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PLA2_a_Ca] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PLA2_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[inact_GEF] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GEF_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GAP_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[GAP] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[PDGFR] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[SHC] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[SHC_a] = 0;
(d[APC_PIP2_Ca_PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# APC_DAG_Ca_PLA2_a:
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[AA] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP_1] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP_2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Grb2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Sos_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Sos] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[RGR] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = -240 - 60;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PLA2_cytosolic] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PLA2_Ca_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = 450;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PLA2_a_Ca] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PLA2_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[inact_GEF] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GEF_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GAP_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[GAP] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[PDGFR] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[SHC] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[SHC_a] = 0;
(d[APC_DAG_Ca_PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# APC_PLA2_a_Ca:
(d[APC_PLA2_a_Ca]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GAP_PKC_a_pool] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP_1_MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_a_MKP_1] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_a_MKP_2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[AA] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP_1] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PPhosphatase2A] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[tot_MKP1] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP_2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Sos_a_Grb2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Grb2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Sos_Grb2] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Sos_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Sos] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_Ca] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_DAG_AA_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_Ca_AA_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_Ca_memb_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_DAG_memb_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_basal_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_AA_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_Ca_DAG] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_DAG] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_DAG_AA] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PKC_cytosolic] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_MAPKK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_RGR] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_ser_RGR] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[craf_1_a_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPK_tyr] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MAPKK_ser] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[RGR] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Ubiquitination] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP_1_ser359_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP_1_a_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[nuc_MAPK_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[MKP1_RNA] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[APC_PLA2_a_Ca] = -480 - 120;
(d[APC_PLA2_a_Ca]/dt)/d[PLA2_cytosolic] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PLA2_Ca_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PIP2_PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PLA2_a_Ca] = 900;
(d[APC_PLA2_a_Ca]/dt)/d[PLA2_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GTP_Ras_GAP] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[inact_GEF] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GEF_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GTP_Ras] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GDP_Ras] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GAP_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[GAP] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[SHC_L_PDGFR] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[PDGFR] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[L_PDGFR] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[SHC] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[SHC_a] = 0;
(d[APC_PLA2_a_Ca]/dt)/d[Internal_L_PDGFR] = 0;
# PLA2_cytosolic:
(d[PLA2_cytosolic]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PLA2_cytosolic]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PLA2_cytosolic]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PLA2_cytosolic_MAPK_a] = 80;
(d[PLA2_cytosolic]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PLA2_cytosolic]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PLA2_cytosolic]/dt)/d[AA] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_a] = -(3.9 * PLA2_cytosolic);
(d[PLA2_cytosolic]/dt)/d[MKP_1] = 0;
(d[PLA2_cytosolic]/dt)/d[PPhosphatase2A] = 0;
(d[PLA2_cytosolic]/dt)/d[tot_MKP1] = 0;
(d[PLA2_cytosolic]/dt)/d[MKP_2] = 0;
(d[PLA2_cytosolic]/dt)/d[Sos_a_Grb2] = 0;
(d[PLA2_cytosolic]/dt)/d[Grb2] = 0;
(d[PLA2_cytosolic]/dt)/d[Sos_Grb2] = 0;
(d[PLA2_cytosolic]/dt)/d[Sos_a] = 0;
(d[PLA2_cytosolic]/dt)/d[Sos] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_Ca] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_basal_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_AA_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_Ca_DAG] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_DAG] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_DAG_AA] = 0;
(d[PLA2_cytosolic]/dt)/d[PKC_cytosolic] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_RGR] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PLA2_cytosolic]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK] = 0;
(d[PLA2_cytosolic]/dt)/d[craf_1_a_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPK_tyr] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MAPKK_ser] = 0;
(d[PLA2_cytosolic]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PLA2_cytosolic]/dt)/d[RGR] = 0;
(d[PLA2_cytosolic]/dt)/d[Ubiquitination] = 0;
(d[PLA2_cytosolic]/dt)/d[MKP_1_ser359_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MKP_1_a_a] = 0;
(d[PLA2_cytosolic]/dt)/d[nuc_MAPK_a] = 0;
(d[PLA2_cytosolic]/dt)/d[MKP1_RNA] = 0;
(d[PLA2_cytosolic]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PLA2_cytosolic]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PLA2_cytosolic]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PLA2_cytosolic]/dt)/d[PLA2_cytosolic] = -(3.9 * MAPK_a) - 0.08 - 0.003;
(d[PLA2_cytosolic]/dt)/d[PLA2_Ca_a] = --0.1;
(d[PLA2_cytosolic]/dt)/d[PIP2_PLA2_a] = --0.5;
(d[PLA2_cytosolic]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PLA2_cytosolic]/dt)/d[PLA2_a_Ca] = 0;
(d[PLA2_cytosolic]/dt)/d[PLA2_a] = 0.17;
(d[PLA2_cytosolic]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PLA2_cytosolic]/dt)/d[GTP_Ras_GAP] = 0;
(d[PLA2_cytosolic]/dt)/d[inact_GEF] = 0;
(d[PLA2_cytosolic]/dt)/d[GEF_a] = 0;
(d[PLA2_cytosolic]/dt)/d[GTP_Ras] = 0;
(d[PLA2_cytosolic]/dt)/d[GDP_Ras] = 0;
(d[PLA2_cytosolic]/dt)/d[GAP_a] = 0;
(d[PLA2_cytosolic]/dt)/d[GAP] = 0;
(d[PLA2_cytosolic]/dt)/d[SHC_L_PDGFR] = 0;
(d[PLA2_cytosolic]/dt)/d[PDGFR] = 0;
(d[PLA2_cytosolic]/dt)/d[L_PDGFR] = 0;
(d[PLA2_cytosolic]/dt)/d[SHC] = 0;
(d[PLA2_cytosolic]/dt)/d[SHC_a] = 0;
(d[PLA2_cytosolic]/dt)/d[Internal_L_PDGFR] = 0;
# PLA2_Ca_a:
(d[PLA2_Ca_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PLA2_Ca_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PLA2_Ca_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PLA2_Ca_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PLA2_Ca_a]/dt)/d[AA] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP_1] = 0;
(d[PLA2_Ca_a]/dt)/d[PPhosphatase2A] = 0;
(d[PLA2_Ca_a]/dt)/d[tot_MKP1] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP_2] = 0;
(d[PLA2_Ca_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PLA2_Ca_a]/dt)/d[Grb2] = 0;
(d[PLA2_Ca_a]/dt)/d[Sos_Grb2] = 0;
(d[PLA2_Ca_a]/dt)/d[Sos_a] = 0;
(d[PLA2_Ca_a]/dt)/d[Sos] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_Ca] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_basal_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_AA_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_DAG] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PLA2_Ca_a]/dt)/d[PKC_cytosolic] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_RGR] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PLA2_Ca_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK] = 0;
(d[PLA2_Ca_a]/dt)/d[craf_1_a_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPK_tyr] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MAPKK_ser] = 0;
(d[PLA2_Ca_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PLA2_Ca_a]/dt)/d[RGR] = 0;
(d[PLA2_Ca_a]/dt)/d[Ubiquitination] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP_1_a_a] = 0;
(d[PLA2_Ca_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PLA2_Ca_a]/dt)/d[MKP1_RNA] = 0;
(d[PLA2_Ca_a]/dt)/d[APC_PLA2_Ca_a] = --21.6 + 5.4;
(d[PLA2_Ca_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PLA2_Ca_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PLA2_Ca_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PLA2_Ca_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PLA2_Ca_a]/dt)/d[PLA2_cytosolic] = 0.08;
(d[PLA2_Ca_a]/dt)/d[PLA2_Ca_a] = -0.1 - 0.03 - 0.034983 - 40.5;
(d[PLA2_Ca_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PLA2_Ca_a]/dt)/d[PIP2_Ca_PLA2_a] = --0.1;
(d[PLA2_Ca_a]/dt)/d[DAG_Ca_PLA2_a] = --4;
(d[PLA2_Ca_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PLA2_Ca_a]/dt)/d[PLA2_a] = 0;
(d[PLA2_Ca_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PLA2_Ca_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PLA2_Ca_a]/dt)/d[inact_GEF] = 0;
(d[PLA2_Ca_a]/dt)/d[GEF_a] = 0;
(d[PLA2_Ca_a]/dt)/d[GTP_Ras] = 0;
(d[PLA2_Ca_a]/dt)/d[GDP_Ras] = 0;
(d[PLA2_Ca_a]/dt)/d[GAP_a] = 0;
(d[PLA2_Ca_a]/dt)/d[GAP] = 0;
(d[PLA2_Ca_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PLA2_Ca_a]/dt)/d[PDGFR] = 0;
(d[PLA2_Ca_a]/dt)/d[L_PDGFR] = 0;
(d[PLA2_Ca_a]/dt)/d[SHC] = 0;
(d[PLA2_Ca_a]/dt)/d[SHC_a] = 0;
(d[PLA2_Ca_a]/dt)/d[Internal_L_PDGFR] = 0;
# PIP2_PLA2_a:
(d[PIP2_PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PIP2_PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PIP2_PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PIP2_PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PIP2_PLA2_a]/dt)/d[AA] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP_1] = 0;
(d[PIP2_PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[PIP2_PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP_2] = 0;
(d[PIP2_PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PIP2_PLA2_a]/dt)/d[Grb2] = 0;
(d[PIP2_PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[PIP2_PLA2_a]/dt)/d[Sos_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[Sos] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PIP2_PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK] = 0;
(d[PIP2_PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[PIP2_PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[RGR] = 0;
(d[PIP2_PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[PIP2_PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = --44.16 + 11.04;
(d[PIP2_PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PIP2_PLA2_a]/dt)/d[PLA2_cytosolic] = 0.003;
(d[PIP2_PLA2_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PIP2_PLA2_a] = -0.5 - 82.8;
(d[PIP2_PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PIP2_PLA2_a]/dt)/d[PLA2_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PIP2_PLA2_a]/dt)/d[inact_GEF] = 0;
(d[PIP2_PLA2_a]/dt)/d[GEF_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[PIP2_PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[PIP2_PLA2_a]/dt)/d[GAP_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[GAP] = 0;
(d[PIP2_PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PIP2_PLA2_a]/dt)/d[PDGFR] = 0;
(d[PIP2_PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[PIP2_PLA2_a]/dt)/d[SHC] = 0;
(d[PIP2_PLA2_a]/dt)/d[SHC_a] = 0;
(d[PIP2_PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# PIP2_Ca_PLA2_a:
(d[PIP2_Ca_PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[AA] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP_1] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP_2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Grb2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Sos_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Sos] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[RGR] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = --144 + 36;
(d[PIP2_Ca_PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PLA2_Ca_a] = 0.03;
(d[PIP2_Ca_PLA2_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = -0.1 - 270;
(d[PIP2_Ca_PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PLA2_a_Ca] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PLA2_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[inact_GEF] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GEF_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GAP_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[GAP] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[PDGFR] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[SHC] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[SHC_a] = 0;
(d[PIP2_Ca_PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# DAG_Ca_PLA2_a:
(d[DAG_Ca_PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[AA] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP_1] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP_2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Grb2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Sos_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Sos] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[RGR] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = --240 + 60;
(d[DAG_Ca_PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PLA2_cytosolic] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PLA2_Ca_a] = 0.034983;
(d[DAG_Ca_PLA2_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = -4 - 450;
(d[DAG_Ca_PLA2_a]/dt)/d[PLA2_a_Ca] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PLA2_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[inact_GEF] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GEF_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GAP_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[GAP] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[PDGFR] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[SHC] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[SHC_a] = 0;
(d[DAG_Ca_PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# PLA2_a_Ca:
(d[PLA2_a_Ca]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PLA2_a_Ca]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PLA2_a_Ca]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PLA2_a_Ca]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PLA2_a_Ca]/dt)/d[AA] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP_1] = 0;
(d[PLA2_a_Ca]/dt)/d[PPhosphatase2A] = 0;
(d[PLA2_a_Ca]/dt)/d[tot_MKP1] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP_2] = 0;
(d[PLA2_a_Ca]/dt)/d[Sos_a_Grb2] = 0;
(d[PLA2_a_Ca]/dt)/d[Grb2] = 0;
(d[PLA2_a_Ca]/dt)/d[Sos_Grb2] = 0;
(d[PLA2_a_Ca]/dt)/d[Sos_a] = 0;
(d[PLA2_a_Ca]/dt)/d[Sos] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_Ca] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_basal_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_AA_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_Ca_DAG] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_DAG] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_DAG_AA] = 0;
(d[PLA2_a_Ca]/dt)/d[PKC_cytosolic] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_RGR] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PLA2_a_Ca]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK] = 0;
(d[PLA2_a_Ca]/dt)/d[craf_1_a_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPK_tyr] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MAPKK_ser] = 0;
(d[PLA2_a_Ca]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PLA2_a_Ca]/dt)/d[RGR] = 0;
(d[PLA2_a_Ca]/dt)/d[Ubiquitination] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP_1_ser359_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP_1_a_a] = 0;
(d[PLA2_a_Ca]/dt)/d[nuc_MAPK_a] = 0;
(d[PLA2_a_Ca]/dt)/d[MKP1_RNA] = 0;
(d[PLA2_a_Ca]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PLA2_a_Ca]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PLA2_a_Ca]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PLA2_a_Ca]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PLA2_a_Ca]/dt)/d[APC_PLA2_a_Ca] = --480 + 120;
(d[PLA2_a_Ca]/dt)/d[PLA2_cytosolic] = 0;
(d[PLA2_a_Ca]/dt)/d[PLA2_Ca_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PIP2_PLA2_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PLA2_a_Ca]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PLA2_a_Ca]/dt)/d[PLA2_a_Ca] = -0.1 - 900;
(d[PLA2_a_Ca]/dt)/d[PLA2_a] = 6 * 0.08;
(d[PLA2_a_Ca]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PLA2_a_Ca]/dt)/d[GTP_Ras_GAP] = 0;
(d[PLA2_a_Ca]/dt)/d[inact_GEF] = 0;
(d[PLA2_a_Ca]/dt)/d[GEF_a] = 0;
(d[PLA2_a_Ca]/dt)/d[GTP_Ras] = 0;
(d[PLA2_a_Ca]/dt)/d[GDP_Ras] = 0;
(d[PLA2_a_Ca]/dt)/d[GAP_a] = 0;
(d[PLA2_a_Ca]/dt)/d[GAP] = 0;
(d[PLA2_a_Ca]/dt)/d[SHC_L_PDGFR] = 0;
(d[PLA2_a_Ca]/dt)/d[PDGFR] = 0;
(d[PLA2_a_Ca]/dt)/d[L_PDGFR] = 0;
(d[PLA2_a_Ca]/dt)/d[SHC] = 0;
(d[PLA2_a_Ca]/dt)/d[SHC_a] = 0;
(d[PLA2_a_Ca]/dt)/d[Internal_L_PDGFR] = 0;
# PLA2_a:
(d[PLA2_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PLA2_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PLA2_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PLA2_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PLA2_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PLA2_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 20;
(d[PLA2_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PLA2_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PLA2_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PLA2_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PLA2_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PLA2_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PLA2_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PLA2_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PLA2_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PLA2_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PLA2_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PLA2_a]/dt)/d[AA] = 0;
(d[PLA2_a]/dt)/d[MAPK_a] = 0;
(d[PLA2_a]/dt)/d[MKP_1] = 0;
(d[PLA2_a]/dt)/d[PPhosphatase2A] = 0;
(d[PLA2_a]/dt)/d[tot_MKP1] = 0;
(d[PLA2_a]/dt)/d[MKP_2] = 0;
(d[PLA2_a]/dt)/d[Sos_a_Grb2] = 0;
(d[PLA2_a]/dt)/d[Grb2] = 0;
(d[PLA2_a]/dt)/d[Sos_Grb2] = 0;
(d[PLA2_a]/dt)/d[Sos_a] = 0;
(d[PLA2_a]/dt)/d[Sos] = 0;
(d[PLA2_a]/dt)/d[PKC_Ca] = 0;
(d[PLA2_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PLA2_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PLA2_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PLA2_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PLA2_a]/dt)/d[PKC_basal_a] = 0;
(d[PLA2_a]/dt)/d[PKC_AA_a] = 0;
(d[PLA2_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[PLA2_a]/dt)/d[PKC_DAG] = 0;
(d[PLA2_a]/dt)/d[PKC_DAG_AA] = 0;
(d[PLA2_a]/dt)/d[PKC_cytosolic] = 0;
(d[PLA2_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PLA2_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PLA2_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PLA2_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PLA2_a]/dt)/d[MAPKK_RGR] = 0;
(d[PLA2_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PLA2_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PLA2_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PLA2_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PLA2_a]/dt)/d[craf_1] = 0;
(d[PLA2_a]/dt)/d[craf_1_a] = 0;
(d[PLA2_a]/dt)/d[MAPKK] = 0;
(d[PLA2_a]/dt)/d[MAPK] = 0;
(d[PLA2_a]/dt)/d[craf_1_a_a] = 0;
(d[PLA2_a]/dt)/d[MAPK_tyr] = 0;
(d[PLA2_a]/dt)/d[MAPKK_a] = 0;
(d[PLA2_a]/dt)/d[MAPKK_ser] = 0;
(d[PLA2_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PLA2_a]/dt)/d[RGR] = 0;
(d[PLA2_a]/dt)/d[Ubiquitination] = 0;
(d[PLA2_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[PLA2_a]/dt)/d[MKP_1_a_a] = 0;
(d[PLA2_a]/dt)/d[nuc_MAPK_a] = 0;
(d[PLA2_a]/dt)/d[MKP1_RNA] = 0;
(d[PLA2_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PLA2_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PLA2_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PLA2_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PLA2_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PLA2_a]/dt)/d[PLA2_cytosolic] = 0;
(d[PLA2_a]/dt)/d[PLA2_Ca_a] = 0;
(d[PLA2_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[PLA2_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PLA2_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PLA2_a]/dt)/d[PLA2_a_Ca] = --0.1;
(d[PLA2_a]/dt)/d[PLA2_a] = -0.48 - 0.17;
(d[PLA2_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PLA2_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[PLA2_a]/dt)/d[inact_GEF] = 0;
(d[PLA2_a]/dt)/d[GEF_a] = 0;
(d[PLA2_a]/dt)/d[GTP_Ras] = 0;
(d[PLA2_a]/dt)/d[GDP_Ras] = 0;
(d[PLA2_a]/dt)/d[GAP_a] = 0;
(d[PLA2_a]/dt)/d[GAP] = 0;
(d[PLA2_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[PLA2_a]/dt)/d[PDGFR] = 0;
(d[PLA2_a]/dt)/d[L_PDGFR] = 0;
(d[PLA2_a]/dt)/d[SHC] = 0;
(d[PLA2_a]/dt)/d[SHC_a] = 0;
(d[PLA2_a]/dt)/d[Internal_L_PDGFR] = 0;
# GDP_Ras_GEF_a:
(d[GDP_Ras_GEF_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[AA] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP_1] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PPhosphatase2A] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[tot_MKP1] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP_2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Sos_a_Grb2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Grb2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Sos_Grb2] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Sos_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Sos] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_Ca] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_basal_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_AA_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_DAG] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_DAG_AA] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PKC_cytosolic] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_RGR] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[craf_1_a_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPK_tyr] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MAPKK_ser] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[RGR] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Ubiquitination] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP_1_a_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[nuc_MAPK_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[MKP1_RNA] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PLA2_cytosolic] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PLA2_Ca_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PLA2_a_Ca] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PLA2_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[GDP_Ras_GEF_a] = -0.08 - 0.02;
(d[GDP_Ras_GEF_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[inact_GEF] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[GEF_a] = 0.198 * GDP_Ras;
(d[GDP_Ras_GEF_a]/dt)/d[GTP_Ras] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[GDP_Ras] = 0.198 * GEF_a;
(d[GDP_Ras_GEF_a]/dt)/d[GAP_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[GAP] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[PDGFR] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[L_PDGFR] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[SHC] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[SHC_a] = 0;
(d[GDP_Ras_GEF_a]/dt)/d[Internal_L_PDGFR] = 0;
# GTP_Ras_GAP:
(d[GTP_Ras_GAP]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GTP_Ras_GAP]/dt)/d[GAP_PKC_a_pool] = 0;
(d[GTP_Ras_GAP]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GTP_Ras_GAP]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GTP_Ras_GAP]/dt)/d[AA] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP_1] = 0;
(d[GTP_Ras_GAP]/dt)/d[PPhosphatase2A] = 0;
(d[GTP_Ras_GAP]/dt)/d[tot_MKP1] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP_2] = 0;
(d[GTP_Ras_GAP]/dt)/d[Sos_a_Grb2] = 0;
(d[GTP_Ras_GAP]/dt)/d[Grb2] = 0;
(d[GTP_Ras_GAP]/dt)/d[Sos_Grb2] = 0;
(d[GTP_Ras_GAP]/dt)/d[Sos_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[Sos] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_Ca] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_basal_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_AA_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_Ca_DAG] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_DAG] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_DAG_AA] = 0;
(d[GTP_Ras_GAP]/dt)/d[PKC_cytosolic] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_RGR] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK] = 0;
(d[GTP_Ras_GAP]/dt)/d[craf_1_a_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPK_tyr] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MAPKK_ser] = 0;
(d[GTP_Ras_GAP]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[RGR] = 0;
(d[GTP_Ras_GAP]/dt)/d[Ubiquitination] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP_1_ser359_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP_1_a_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[nuc_MAPK_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[MKP1_RNA] = 0;
(d[GTP_Ras_GAP]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GTP_Ras_GAP]/dt)/d[PLA2_cytosolic] = 0;
(d[GTP_Ras_GAP]/dt)/d[PLA2_Ca_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PIP2_PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[PLA2_a_Ca] = 0;
(d[GTP_Ras_GAP]/dt)/d[PLA2_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[GTP_Ras_GAP] = -1000 - 10;
(d[GTP_Ras_GAP]/dt)/d[inact_GEF] = 0;
(d[GTP_Ras_GAP]/dt)/d[GEF_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[GTP_Ras] = 999.6 * GAP;
(d[GTP_Ras_GAP]/dt)/d[GDP_Ras] = 0;
(d[GTP_Ras_GAP]/dt)/d[GAP_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[GAP] = 999.6 * GTP_Ras;
(d[GTP_Ras_GAP]/dt)/d[SHC_L_PDGFR] = 0;
(d[GTP_Ras_GAP]/dt)/d[PDGFR] = 0;
(d[GTP_Ras_GAP]/dt)/d[L_PDGFR] = 0;
(d[GTP_Ras_GAP]/dt)/d[SHC] = 0;
(d[GTP_Ras_GAP]/dt)/d[SHC_a] = 0;
(d[GTP_Ras_GAP]/dt)/d[Internal_L_PDGFR] = 0;
# inact_GEF:
(d[inact_GEF]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[inact_GEF]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[inact_GEF]/dt)/d[GAP_PKC_a_pool] = 0;
(d[inact_GEF]/dt)/d[inact_GEF_PKC_a_pool] = 16;
(d[inact_GEF]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[inact_GEF]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[inact_GEF]/dt)/d[MKP_1_MAPK_a] = 0;
(d[inact_GEF]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[inact_GEF]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[inact_GEF]/dt)/d[MAPK_a_MKP_1] = 0;
(d[inact_GEF]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[inact_GEF]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[inact_GEF]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[inact_GEF]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[inact_GEF]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[inact_GEF]/dt)/d[MAPK_a_MKP_2] = 0;
(d[inact_GEF]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[inact_GEF]/dt)/d[AA] = 0;
(d[inact_GEF]/dt)/d[MAPK_a] = 0;
(d[inact_GEF]/dt)/d[MKP_1] = 0;
(d[inact_GEF]/dt)/d[PPhosphatase2A] = 0;
(d[inact_GEF]/dt)/d[tot_MKP1] = 0;
(d[inact_GEF]/dt)/d[MKP_2] = 0;
(d[inact_GEF]/dt)/d[Sos_a_Grb2] = 0;
(d[inact_GEF]/dt)/d[Grb2] = 0;
(d[inact_GEF]/dt)/d[Sos_Grb2] = 0;
(d[inact_GEF]/dt)/d[Sos_a] = 0;
(d[inact_GEF]/dt)/d[Sos] = 0;
(d[inact_GEF]/dt)/d[PKC_Ca] = 0;
(d[inact_GEF]/dt)/d[PKC_DAG_AA_a] = -(0.3 * inact_GEF);
(d[inact_GEF]/dt)/d[PKC_Ca_AA_a] = -(0.3 * inact_GEF);
(d[inact_GEF]/dt)/d[PKC_Ca_memb_a] = -(0.3 * inact_GEF);
(d[inact_GEF]/dt)/d[PKC_DAG_memb_a] = -(0.3 * inact_GEF);
(d[inact_GEF]/dt)/d[PKC_basal_a] = -(0.3 * inact_GEF);
(d[inact_GEF]/dt)/d[PKC_AA_a] = -(0.3 * inact_GEF);
(d[inact_GEF]/dt)/d[PKC_Ca_DAG] = 0;
(d[inact_GEF]/dt)/d[PKC_DAG] = 0;
(d[inact_GEF]/dt)/d[PKC_DAG_AA] = 0;
(d[inact_GEF]/dt)/d[PKC_cytosolic] = 0;
(d[inact_GEF]/dt)/d[MAPK_MAPKK_a] = 0;
(d[inact_GEF]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[inact_GEF]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[inact_GEF]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[inact_GEF]/dt)/d[MAPKK_RGR] = 0;
(d[inact_GEF]/dt)/d[MAPKK_ser_RGR] = 0;
(d[inact_GEF]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[inact_GEF]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[inact_GEF]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[inact_GEF]/dt)/d[craf_1] = 0;
(d[inact_GEF]/dt)/d[craf_1_a] = 0;
(d[inact_GEF]/dt)/d[MAPKK] = 0;
(d[inact_GEF]/dt)/d[MAPK] = 0;
(d[inact_GEF]/dt)/d[craf_1_a_a] = 0;
(d[inact_GEF]/dt)/d[MAPK_tyr] = 0;
(d[inact_GEF]/dt)/d[MAPKK_a] = 0;
(d[inact_GEF]/dt)/d[MAPKK_ser] = 0;
(d[inact_GEF]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[inact_GEF]/dt)/d[RGR] = 0;
(d[inact_GEF]/dt)/d[Ubiquitination] = 0;
(d[inact_GEF]/dt)/d[MKP_1_ser359_a] = 0;
(d[inact_GEF]/dt)/d[MKP_1_a_a] = 0;
(d[inact_GEF]/dt)/d[nuc_MAPK_a] = 0;
(d[inact_GEF]/dt)/d[MKP1_RNA] = 0;
(d[inact_GEF]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[inact_GEF]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[inact_GEF]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[inact_GEF]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[inact_GEF]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[inact_GEF]/dt)/d[PLA2_cytosolic] = 0;
(d[inact_GEF]/dt)/d[PLA2_Ca_a] = 0;
(d[inact_GEF]/dt)/d[PIP2_PLA2_a] = 0;
(d[inact_GEF]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[inact_GEF]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[inact_GEF]/dt)/d[PLA2_a_Ca] = 0;
(d[inact_GEF]/dt)/d[PLA2_a] = 0;
(d[inact_GEF]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[inact_GEF]/dt)/d[GTP_Ras_GAP] = 0;
(d[inact_GEF]/dt)/d[inact_GEF] = -(0.3 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a));
(d[inact_GEF]/dt)/d[GEF_a] = 0.1;
(d[inact_GEF]/dt)/d[GTP_Ras] = 0;
(d[inact_GEF]/dt)/d[GDP_Ras] = 0;
(d[inact_GEF]/dt)/d[GAP_a] = 0;
(d[inact_GEF]/dt)/d[GAP] = 0;
(d[inact_GEF]/dt)/d[SHC_L_PDGFR] = 0;
(d[inact_GEF]/dt)/d[PDGFR] = 0;
(d[inact_GEF]/dt)/d[L_PDGFR] = 0;
(d[inact_GEF]/dt)/d[SHC] = 0;
(d[inact_GEF]/dt)/d[SHC_a] = 0;
(d[inact_GEF]/dt)/d[Internal_L_PDGFR] = 0;
# GEF_a:
(d[GEF_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[GEF_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GEF_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[GEF_a]/dt)/d[inact_GEF_PKC_a_pool] = 4;
(d[GEF_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GEF_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GEF_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GEF_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GEF_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GEF_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GEF_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GEF_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GEF_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GEF_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GEF_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GEF_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GEF_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GEF_a]/dt)/d[AA] = 0;
(d[GEF_a]/dt)/d[MAPK_a] = 0;
(d[GEF_a]/dt)/d[MKP_1] = 0;
(d[GEF_a]/dt)/d[PPhosphatase2A] = 0;
(d[GEF_a]/dt)/d[tot_MKP1] = 0;
(d[GEF_a]/dt)/d[MKP_2] = 0;
(d[GEF_a]/dt)/d[Sos_a_Grb2] = 0;
(d[GEF_a]/dt)/d[Grb2] = 0;
(d[GEF_a]/dt)/d[Sos_Grb2] = 0;
(d[GEF_a]/dt)/d[Sos_a] = 0;
(d[GEF_a]/dt)/d[Sos] = 0;
(d[GEF_a]/dt)/d[PKC_Ca] = 0;
(d[GEF_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GEF_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GEF_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GEF_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GEF_a]/dt)/d[PKC_basal_a] = 0;
(d[GEF_a]/dt)/d[PKC_AA_a] = 0;
(d[GEF_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[GEF_a]/dt)/d[PKC_DAG] = 0;
(d[GEF_a]/dt)/d[PKC_DAG_AA] = 0;
(d[GEF_a]/dt)/d[PKC_cytosolic] = 0;
(d[GEF_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GEF_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GEF_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GEF_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GEF_a]/dt)/d[MAPKK_RGR] = 0;
(d[GEF_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GEF_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GEF_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GEF_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GEF_a]/dt)/d[craf_1] = 0;
(d[GEF_a]/dt)/d[craf_1_a] = 0;
(d[GEF_a]/dt)/d[MAPKK] = 0;
(d[GEF_a]/dt)/d[MAPK] = 0;
(d[GEF_a]/dt)/d[craf_1_a_a] = 0;
(d[GEF_a]/dt)/d[MAPK_tyr] = 0;
(d[GEF_a]/dt)/d[MAPKK_a] = 0;
(d[GEF_a]/dt)/d[MAPKK_ser] = 0;
(d[GEF_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GEF_a]/dt)/d[RGR] = 0;
(d[GEF_a]/dt)/d[Ubiquitination] = 0;
(d[GEF_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[GEF_a]/dt)/d[MKP_1_a_a] = 0;
(d[GEF_a]/dt)/d[nuc_MAPK_a] = 0;
(d[GEF_a]/dt)/d[MKP1_RNA] = 0;
(d[GEF_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GEF_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GEF_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GEF_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GEF_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GEF_a]/dt)/d[PLA2_cytosolic] = 0;
(d[GEF_a]/dt)/d[PLA2_Ca_a] = 0;
(d[GEF_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[GEF_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GEF_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GEF_a]/dt)/d[PLA2_a_Ca] = 0;
(d[GEF_a]/dt)/d[PLA2_a] = 0;
(d[GEF_a]/dt)/d[GDP_Ras_GEF_a] = --0.08 + 0.02;
(d[GEF_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[GEF_a]/dt)/d[inact_GEF] = 0;
(d[GEF_a]/dt)/d[GEF_a] = -0.1 - 0.198 * GDP_Ras;
(d[GEF_a]/dt)/d[GTP_Ras] = 0;
(d[GEF_a]/dt)/d[GDP_Ras] = -(0.198 * GEF_a);
(d[GEF_a]/dt)/d[GAP_a] = 0;
(d[GEF_a]/dt)/d[GAP] = 0;
(d[GEF_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[GEF_a]/dt)/d[PDGFR] = 0;
(d[GEF_a]/dt)/d[L_PDGFR] = 0;
(d[GEF_a]/dt)/d[SHC] = 0;
(d[GEF_a]/dt)/d[SHC_a] = 0;
(d[GEF_a]/dt)/d[Internal_L_PDGFR] = 0;
# GTP_Ras:
(d[GTP_Ras]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0.02;
(d[GTP_Ras]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GTP_Ras]/dt)/d[GAP_PKC_a_pool] = 0;
(d[GTP_Ras]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GTP_Ras]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GTP_Ras]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GTP_Ras]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GTP_Ras]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GTP_Ras]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GTP_Ras]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GTP_Ras]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GTP_Ras]/dt)/d[AA] = 0;
(d[GTP_Ras]/dt)/d[MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[MKP_1] = 0;
(d[GTP_Ras]/dt)/d[PPhosphatase2A] = 0;
(d[GTP_Ras]/dt)/d[tot_MKP1] = 0;
(d[GTP_Ras]/dt)/d[MKP_2] = 0;
(d[GTP_Ras]/dt)/d[Sos_a_Grb2] = 0;
(d[GTP_Ras]/dt)/d[Grb2] = 0;
(d[GTP_Ras]/dt)/d[Sos_Grb2] = 0;
(d[GTP_Ras]/dt)/d[Sos_a] = 0;
(d[GTP_Ras]/dt)/d[Sos] = 0;
(d[GTP_Ras]/dt)/d[PKC_Ca] = 0;
(d[GTP_Ras]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GTP_Ras]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GTP_Ras]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GTP_Ras]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GTP_Ras]/dt)/d[PKC_basal_a] = 0;
(d[GTP_Ras]/dt)/d[PKC_AA_a] = 0;
(d[GTP_Ras]/dt)/d[PKC_Ca_DAG] = 0;
(d[GTP_Ras]/dt)/d[PKC_DAG] = 0;
(d[GTP_Ras]/dt)/d[PKC_DAG_AA] = 0;
(d[GTP_Ras]/dt)/d[PKC_cytosolic] = 0;
(d[GTP_Ras]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GTP_Ras]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_RGR] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GTP_Ras]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GTP_Ras]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GTP_Ras]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[craf_1] = -(6 * GTP_Ras);
(d[GTP_Ras]/dt)/d[craf_1_a] = -(60 * GTP_Ras);
(d[GTP_Ras]/dt)/d[MAPKK] = 0;
(d[GTP_Ras]/dt)/d[MAPK] = 0;
(d[GTP_Ras]/dt)/d[craf_1_a_a] = 0;
(d[GTP_Ras]/dt)/d[MAPK_tyr] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_a] = 0;
(d[GTP_Ras]/dt)/d[MAPKK_ser] = 0;
(d[GTP_Ras]/dt)/d[Raf_GTP_Ras_a] = 0.5;
(d[GTP_Ras]/dt)/d[RGR] = 1;
(d[GTP_Ras]/dt)/d[Ubiquitination] = 0;
(d[GTP_Ras]/dt)/d[MKP_1_ser359_a] = 0;
(d[GTP_Ras]/dt)/d[MKP_1_a_a] = 0;
(d[GTP_Ras]/dt)/d[nuc_MAPK_a] = 0;
(d[GTP_Ras]/dt)/d[MKP1_RNA] = 0;
(d[GTP_Ras]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GTP_Ras]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GTP_Ras]/dt)/d[PLA2_cytosolic] = 0;
(d[GTP_Ras]/dt)/d[PLA2_Ca_a] = 0;
(d[GTP_Ras]/dt)/d[PIP2_PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[PLA2_a_Ca] = 0;
(d[GTP_Ras]/dt)/d[PLA2_a] = 0;
(d[GTP_Ras]/dt)/d[GDP_Ras_GEF_a] = 0.02;
(d[GTP_Ras]/dt)/d[GTP_Ras_GAP] = --1000;
(d[GTP_Ras]/dt)/d[inact_GEF] = 0;
(d[GTP_Ras]/dt)/d[GEF_a] = 0;
(d[GTP_Ras]/dt)/d[GTP_Ras] = -(60 * craf_1_a) - 6 * craf_1 - 0.0001 - 999.6 * GAP;
(d[GTP_Ras]/dt)/d[GDP_Ras] = 0;
(d[GTP_Ras]/dt)/d[GAP_a] = 0;
(d[GTP_Ras]/dt)/d[GAP] = -(999.6 * GTP_Ras);
(d[GTP_Ras]/dt)/d[SHC_L_PDGFR] = 0;
(d[GTP_Ras]/dt)/d[PDGFR] = 0;
(d[GTP_Ras]/dt)/d[L_PDGFR] = 0;
(d[GTP_Ras]/dt)/d[SHC] = 0;
(d[GTP_Ras]/dt)/d[SHC_a] = 0;
(d[GTP_Ras]/dt)/d[Internal_L_PDGFR] = 0;
# GDP_Ras:
(d[GDP_Ras]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0.08;
(d[GDP_Ras]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GDP_Ras]/dt)/d[GAP_PKC_a_pool] = 0;
(d[GDP_Ras]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GDP_Ras]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GDP_Ras]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GDP_Ras]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GDP_Ras]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GDP_Ras]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GDP_Ras]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GDP_Ras]/dt)/d[Shc_a_Sos_Grb2] = -(0.198 * GDP_Ras);
(d[GDP_Ras]/dt)/d[AA] = 0;
(d[GDP_Ras]/dt)/d[MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[MKP_1] = 0;
(d[GDP_Ras]/dt)/d[PPhosphatase2A] = 0;
(d[GDP_Ras]/dt)/d[tot_MKP1] = 0;
(d[GDP_Ras]/dt)/d[MKP_2] = 0;
(d[GDP_Ras]/dt)/d[Sos_a_Grb2] = 0;
(d[GDP_Ras]/dt)/d[Grb2] = 0;
(d[GDP_Ras]/dt)/d[Sos_Grb2] = 0;
(d[GDP_Ras]/dt)/d[Sos_a] = 0;
(d[GDP_Ras]/dt)/d[Sos] = 0;
(d[GDP_Ras]/dt)/d[PKC_Ca] = 0;
(d[GDP_Ras]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GDP_Ras]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GDP_Ras]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GDP_Ras]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GDP_Ras]/dt)/d[PKC_basal_a] = 0;
(d[GDP_Ras]/dt)/d[PKC_AA_a] = 0;
(d[GDP_Ras]/dt)/d[PKC_Ca_DAG] = 0;
(d[GDP_Ras]/dt)/d[PKC_DAG] = 0;
(d[GDP_Ras]/dt)/d[PKC_DAG_AA] = 0;
(d[GDP_Ras]/dt)/d[PKC_cytosolic] = 0;
(d[GDP_Ras]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GDP_Ras]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_RGR] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GDP_Ras]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GDP_Ras]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GDP_Ras]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[craf_1] = 0;
(d[GDP_Ras]/dt)/d[craf_1_a] = 0;
(d[GDP_Ras]/dt)/d[MAPKK] = 0;
(d[GDP_Ras]/dt)/d[MAPK] = 0;
(d[GDP_Ras]/dt)/d[craf_1_a_a] = 0;
(d[GDP_Ras]/dt)/d[MAPK_tyr] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_a] = 0;
(d[GDP_Ras]/dt)/d[MAPKK_ser] = 0;
(d[GDP_Ras]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GDP_Ras]/dt)/d[RGR] = 0;
(d[GDP_Ras]/dt)/d[Ubiquitination] = 0;
(d[GDP_Ras]/dt)/d[MKP_1_ser359_a] = 0;
(d[GDP_Ras]/dt)/d[MKP_1_a_a] = 0;
(d[GDP_Ras]/dt)/d[nuc_MAPK_a] = 0;
(d[GDP_Ras]/dt)/d[MKP1_RNA] = 0;
(d[GDP_Ras]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GDP_Ras]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GDP_Ras]/dt)/d[PLA2_cytosolic] = 0;
(d[GDP_Ras]/dt)/d[PLA2_Ca_a] = 0;
(d[GDP_Ras]/dt)/d[PIP2_PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[PLA2_a_Ca] = 0;
(d[GDP_Ras]/dt)/d[PLA2_a] = 0;
(d[GDP_Ras]/dt)/d[GDP_Ras_GEF_a] = --0.08;
(d[GDP_Ras]/dt)/d[GTP_Ras_GAP] = 10;
(d[GDP_Ras]/dt)/d[inact_GEF] = 0;
(d[GDP_Ras]/dt)/d[GEF_a] = -(0.198 * GDP_Ras);
(d[GDP_Ras]/dt)/d[GTP_Ras] = 0.0001;
(d[GDP_Ras]/dt)/d[GDP_Ras] = -(0.198 * Shc_a_Sos_Grb2) - 0.198 * GEF_a;
(d[GDP_Ras]/dt)/d[GAP_a] = 0;
(d[GDP_Ras]/dt)/d[GAP] = 0;
(d[GDP_Ras]/dt)/d[SHC_L_PDGFR] = 0;
(d[GDP_Ras]/dt)/d[PDGFR] = 0;
(d[GDP_Ras]/dt)/d[L_PDGFR] = 0;
(d[GDP_Ras]/dt)/d[SHC] = 0;
(d[GDP_Ras]/dt)/d[SHC_a] = 0;
(d[GDP_Ras]/dt)/d[Internal_L_PDGFR] = 0;
# GAP_a:
(d[GAP_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[GAP_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GAP_a]/dt)/d[GAP_PKC_a_pool] = 25;
(d[GAP_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GAP_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GAP_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GAP_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GAP_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GAP_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GAP_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GAP_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GAP_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GAP_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GAP_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GAP_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GAP_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GAP_a]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GAP_a]/dt)/d[AA] = 0;
(d[GAP_a]/dt)/d[MAPK_a] = 0;
(d[GAP_a]/dt)/d[MKP_1] = 0;
(d[GAP_a]/dt)/d[PPhosphatase2A] = 0;
(d[GAP_a]/dt)/d[tot_MKP1] = 0;
(d[GAP_a]/dt)/d[MKP_2] = 0;
(d[GAP_a]/dt)/d[Sos_a_Grb2] = 0;
(d[GAP_a]/dt)/d[Grb2] = 0;
(d[GAP_a]/dt)/d[Sos_Grb2] = 0;
(d[GAP_a]/dt)/d[Sos_a] = 0;
(d[GAP_a]/dt)/d[Sos] = 0;
(d[GAP_a]/dt)/d[PKC_Ca] = 0;
(d[GAP_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[GAP_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[GAP_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[GAP_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[GAP_a]/dt)/d[PKC_basal_a] = 0;
(d[GAP_a]/dt)/d[PKC_AA_a] = 0;
(d[GAP_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[GAP_a]/dt)/d[PKC_DAG] = 0;
(d[GAP_a]/dt)/d[PKC_DAG_AA] = 0;
(d[GAP_a]/dt)/d[PKC_cytosolic] = 0;
(d[GAP_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GAP_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GAP_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GAP_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GAP_a]/dt)/d[MAPKK_RGR] = 0;
(d[GAP_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GAP_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GAP_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GAP_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GAP_a]/dt)/d[craf_1] = 0;
(d[GAP_a]/dt)/d[craf_1_a] = 0;
(d[GAP_a]/dt)/d[MAPKK] = 0;
(d[GAP_a]/dt)/d[MAPK] = 0;
(d[GAP_a]/dt)/d[craf_1_a_a] = 0;
(d[GAP_a]/dt)/d[MAPK_tyr] = 0;
(d[GAP_a]/dt)/d[MAPKK_a] = 0;
(d[GAP_a]/dt)/d[MAPKK_ser] = 0;
(d[GAP_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GAP_a]/dt)/d[RGR] = 0;
(d[GAP_a]/dt)/d[Ubiquitination] = 0;
(d[GAP_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[GAP_a]/dt)/d[MKP_1_a_a] = 0;
(d[GAP_a]/dt)/d[nuc_MAPK_a] = 0;
(d[GAP_a]/dt)/d[MKP1_RNA] = 0;
(d[GAP_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GAP_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GAP_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GAP_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GAP_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GAP_a]/dt)/d[PLA2_cytosolic] = 0;
(d[GAP_a]/dt)/d[PLA2_Ca_a] = 0;
(d[GAP_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[GAP_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GAP_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GAP_a]/dt)/d[PLA2_a_Ca] = 0;
(d[GAP_a]/dt)/d[PLA2_a] = 0;
(d[GAP_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[GAP_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[GAP_a]/dt)/d[inact_GEF] = 0;
(d[GAP_a]/dt)/d[GEF_a] = 0;
(d[GAP_a]/dt)/d[GTP_Ras] = 0;
(d[GAP_a]/dt)/d[GDP_Ras] = 0;
(d[GAP_a]/dt)/d[GAP_a] = -0.1;
(d[GAP_a]/dt)/d[GAP] = 0;
(d[GAP_a]/dt)/d[SHC_L_PDGFR] = 0;
(d[GAP_a]/dt)/d[PDGFR] = 0;
(d[GAP_a]/dt)/d[L_PDGFR] = 0;
(d[GAP_a]/dt)/d[SHC] = 0;
(d[GAP_a]/dt)/d[SHC_a] = 0;
(d[GAP_a]/dt)/d[Internal_L_PDGFR] = 0;
# GAP:
(d[GAP]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[GAP]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[GAP]/dt)/d[GAP_PKC_a_pool] = 100;
(d[GAP]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[GAP]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[GAP]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[GAP]/dt)/d[MKP_1_MAPK_a] = 0;
(d[GAP]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[GAP]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[GAP]/dt)/d[MAPK_a_MKP_1] = 0;
(d[GAP]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[GAP]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[GAP]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[GAP]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[GAP]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[GAP]/dt)/d[MAPK_a_MKP_2] = 0;
(d[GAP]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[GAP]/dt)/d[AA] = 0;
(d[GAP]/dt)/d[MAPK_a] = 0;
(d[GAP]/dt)/d[MKP_1] = 0;
(d[GAP]/dt)/d[PPhosphatase2A] = 0;
(d[GAP]/dt)/d[tot_MKP1] = 0;
(d[GAP]/dt)/d[MKP_2] = 0;
(d[GAP]/dt)/d[Sos_a_Grb2] = 0;
(d[GAP]/dt)/d[Grb2] = 0;
(d[GAP]/dt)/d[Sos_Grb2] = 0;
(d[GAP]/dt)/d[Sos_a] = 0;
(d[GAP]/dt)/d[Sos] = 0;
(d[GAP]/dt)/d[PKC_Ca] = 0;
(d[GAP]/dt)/d[PKC_DAG_AA_a] = -(1.875 * GAP);
(d[GAP]/dt)/d[PKC_Ca_AA_a] = -(1.875 * GAP);
(d[GAP]/dt)/d[PKC_Ca_memb_a] = -(1.875 * GAP);
(d[GAP]/dt)/d[PKC_DAG_memb_a] = -(1.875 * GAP);
(d[GAP]/dt)/d[PKC_basal_a] = -(1.875 * GAP);
(d[GAP]/dt)/d[PKC_AA_a] = -(1.875 * GAP);
(d[GAP]/dt)/d[PKC_Ca_DAG] = 0;
(d[GAP]/dt)/d[PKC_DAG] = 0;
(d[GAP]/dt)/d[PKC_DAG_AA] = 0;
(d[GAP]/dt)/d[PKC_cytosolic] = 0;
(d[GAP]/dt)/d[MAPK_MAPKK_a] = 0;
(d[GAP]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[GAP]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[GAP]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[GAP]/dt)/d[MAPKK_RGR] = 0;
(d[GAP]/dt)/d[MAPKK_ser_RGR] = 0;
(d[GAP]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[GAP]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[GAP]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[GAP]/dt)/d[craf_1] = 0;
(d[GAP]/dt)/d[craf_1_a] = 0;
(d[GAP]/dt)/d[MAPKK] = 0;
(d[GAP]/dt)/d[MAPK] = 0;
(d[GAP]/dt)/d[craf_1_a_a] = 0;
(d[GAP]/dt)/d[MAPK_tyr] = 0;
(d[GAP]/dt)/d[MAPKK_a] = 0;
(d[GAP]/dt)/d[MAPKK_ser] = 0;
(d[GAP]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[GAP]/dt)/d[RGR] = 0;
(d[GAP]/dt)/d[Ubiquitination] = 0;
(d[GAP]/dt)/d[MKP_1_ser359_a] = 0;
(d[GAP]/dt)/d[MKP_1_a_a] = 0;
(d[GAP]/dt)/d[nuc_MAPK_a] = 0;
(d[GAP]/dt)/d[MKP1_RNA] = 0;
(d[GAP]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[GAP]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[GAP]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[GAP]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[GAP]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[GAP]/dt)/d[PLA2_cytosolic] = 0;
(d[GAP]/dt)/d[PLA2_Ca_a] = 0;
(d[GAP]/dt)/d[PIP2_PLA2_a] = 0;
(d[GAP]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[GAP]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[GAP]/dt)/d[PLA2_a_Ca] = 0;
(d[GAP]/dt)/d[PLA2_a] = 0;
(d[GAP]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[GAP]/dt)/d[GTP_Ras_GAP] = --1000 + 10;
(d[GAP]/dt)/d[inact_GEF] = 0;
(d[GAP]/dt)/d[GEF_a] = 0;
(d[GAP]/dt)/d[GTP_Ras] = -(999.6 * GAP);
(d[GAP]/dt)/d[GDP_Ras] = 0;
(d[GAP]/dt)/d[GAP_a] = 0.1;
(d[GAP]/dt)/d[GAP] = -(1.875 * (PKC_DAG_AA_a + PKC_Ca_AA_a + PKC_AA_a + PKC_Ca_memb_a + PKC_DAG_memb_a + PKC_basal_a)) - 999.6 * GTP_Ras;
(d[GAP]/dt)/d[SHC_L_PDGFR] = 0;
(d[GAP]/dt)/d[PDGFR] = 0;
(d[GAP]/dt)/d[L_PDGFR] = 0;
(d[GAP]/dt)/d[SHC] = 0;
(d[GAP]/dt)/d[SHC_a] = 0;
(d[GAP]/dt)/d[Internal_L_PDGFR] = 0;
# SHC_L_PDGFR:
(d[SHC_L_PDGFR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[SHC_L_PDGFR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[SHC_L_PDGFR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[SHC_L_PDGFR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[SHC_L_PDGFR]/dt)/d[AA] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP_1] = 0;
(d[SHC_L_PDGFR]/dt)/d[PPhosphatase2A] = 0;
(d[SHC_L_PDGFR]/dt)/d[tot_MKP1] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP_2] = 0;
(d[SHC_L_PDGFR]/dt)/d[Sos_a_Grb2] = 0;
(d[SHC_L_PDGFR]/dt)/d[Grb2] = 0;
(d[SHC_L_PDGFR]/dt)/d[Sos_Grb2] = 0;
(d[SHC_L_PDGFR]/dt)/d[Sos_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[Sos] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_Ca] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_basal_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_AA_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_Ca_DAG] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_DAG] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_DAG_AA] = 0;
(d[SHC_L_PDGFR]/dt)/d[PKC_cytosolic] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_RGR] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_ser_RGR] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK] = 0;
(d[SHC_L_PDGFR]/dt)/d[craf_1_a_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPK_tyr] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MAPKK_ser] = 0;
(d[SHC_L_PDGFR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[RGR] = 0;
(d[SHC_L_PDGFR]/dt)/d[Ubiquitination] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP_1_ser359_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP_1_a_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[nuc_MAPK_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[MKP1_RNA] = 0;
(d[SHC_L_PDGFR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[SHC_L_PDGFR]/dt)/d[PLA2_cytosolic] = 0;
(d[SHC_L_PDGFR]/dt)/d[PLA2_Ca_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PIP2_PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[PLA2_a_Ca] = 0;
(d[SHC_L_PDGFR]/dt)/d[PLA2_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[GTP_Ras_GAP] = 0;
(d[SHC_L_PDGFR]/dt)/d[inact_GEF] = 0;
(d[SHC_L_PDGFR]/dt)/d[GEF_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[GTP_Ras] = 0;
(d[SHC_L_PDGFR]/dt)/d[GDP_Ras] = 0;
(d[SHC_L_PDGFR]/dt)/d[GAP_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[GAP] = 0;
(d[SHC_L_PDGFR]/dt)/d[SHC_L_PDGFR] = -0.2 - 0.05;
(d[SHC_L_PDGFR]/dt)/d[PDGFR] = 0;
(d[SHC_L_PDGFR]/dt)/d[L_PDGFR] = 0.3 * SHC;
(d[SHC_L_PDGFR]/dt)/d[SHC] = 0.3 * L_PDGFR;
(d[SHC_L_PDGFR]/dt)/d[SHC_a] = 0;
(d[SHC_L_PDGFR]/dt)/d[Internal_L_PDGFR] = 0;
# PDGFR:
(d[PDGFR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[PDGFR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[PDGFR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[PDGFR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[PDGFR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[PDGFR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[PDGFR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[PDGFR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[PDGFR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[PDGFR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[PDGFR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[PDGFR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[PDGFR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[PDGFR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[PDGFR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[PDGFR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[PDGFR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[PDGFR]/dt)/d[AA] = 0;
(d[PDGFR]/dt)/d[MAPK_a] = 0;
(d[PDGFR]/dt)/d[MKP_1] = 0;
(d[PDGFR]/dt)/d[PPhosphatase2A] = 0;
(d[PDGFR]/dt)/d[tot_MKP1] = 0;
(d[PDGFR]/dt)/d[MKP_2] = 0;
(d[PDGFR]/dt)/d[Sos_a_Grb2] = 0;
(d[PDGFR]/dt)/d[Grb2] = 0;
(d[PDGFR]/dt)/d[Sos_Grb2] = 0;
(d[PDGFR]/dt)/d[Sos_a] = 0;
(d[PDGFR]/dt)/d[Sos] = 0;
(d[PDGFR]/dt)/d[PKC_Ca] = 0;
(d[PDGFR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[PDGFR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[PDGFR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[PDGFR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[PDGFR]/dt)/d[PKC_basal_a] = 0;
(d[PDGFR]/dt)/d[PKC_AA_a] = 0;
(d[PDGFR]/dt)/d[PKC_Ca_DAG] = 0;
(d[PDGFR]/dt)/d[PKC_DAG] = 0;
(d[PDGFR]/dt)/d[PKC_DAG_AA] = 0;
(d[PDGFR]/dt)/d[PKC_cytosolic] = 0;
(d[PDGFR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[PDGFR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[PDGFR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[PDGFR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[PDGFR]/dt)/d[MAPKK_RGR] = 0;
(d[PDGFR]/dt)/d[MAPKK_ser_RGR] = 0;
(d[PDGFR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[PDGFR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[PDGFR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[PDGFR]/dt)/d[craf_1] = 0;
(d[PDGFR]/dt)/d[craf_1_a] = 0;
(d[PDGFR]/dt)/d[MAPKK] = 0;
(d[PDGFR]/dt)/d[MAPK] = 0;
(d[PDGFR]/dt)/d[craf_1_a_a] = 0;
(d[PDGFR]/dt)/d[MAPK_tyr] = 0;
(d[PDGFR]/dt)/d[MAPKK_a] = 0;
(d[PDGFR]/dt)/d[MAPKK_ser] = 0;
(d[PDGFR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[PDGFR]/dt)/d[RGR] = 0;
(d[PDGFR]/dt)/d[Ubiquitination] = 0;
(d[PDGFR]/dt)/d[MKP_1_ser359_a] = 0;
(d[PDGFR]/dt)/d[MKP_1_a_a] = 0;
(d[PDGFR]/dt)/d[nuc_MAPK_a] = 0;
(d[PDGFR]/dt)/d[MKP1_RNA] = 0;
(d[PDGFR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[PDGFR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[PDGFR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[PDGFR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[PDGFR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[PDGFR]/dt)/d[PLA2_cytosolic] = 0;
(d[PDGFR]/dt)/d[PLA2_Ca_a] = 0;
(d[PDGFR]/dt)/d[PIP2_PLA2_a] = 0;
(d[PDGFR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[PDGFR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[PDGFR]/dt)/d[PLA2_a_Ca] = 0;
(d[PDGFR]/dt)/d[PLA2_a] = 0;
(d[PDGFR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[PDGFR]/dt)/d[GTP_Ras_GAP] = 0;
(d[PDGFR]/dt)/d[inact_GEF] = 0;
(d[PDGFR]/dt)/d[GEF_a] = 0;
(d[PDGFR]/dt)/d[GTP_Ras] = 0;
(d[PDGFR]/dt)/d[GDP_Ras] = 0;
(d[PDGFR]/dt)/d[GAP_a] = 0;
(d[PDGFR]/dt)/d[GAP] = 0;
(d[PDGFR]/dt)/d[SHC_L_PDGFR] = 0;
(d[PDGFR]/dt)/d[PDGFR] = -(200 * piecewise(geq(time, 300), 0, 0.0015));
(d[PDGFR]/dt)/d[L_PDGFR] = 0.1;
(d[PDGFR]/dt)/d[SHC] = 0;
(d[PDGFR]/dt)/d[SHC_a] = 0;
(d[PDGFR]/dt)/d[Internal_L_PDGFR] = 0;
# L_PDGFR:
(d[L_PDGFR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[L_PDGFR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[L_PDGFR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[L_PDGFR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[L_PDGFR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[L_PDGFR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[L_PDGFR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[L_PDGFR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[L_PDGFR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[L_PDGFR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[L_PDGFR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[L_PDGFR]/dt)/d[AA] = 0;
(d[L_PDGFR]/dt)/d[MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[MKP_1] = 0;
(d[L_PDGFR]/dt)/d[PPhosphatase2A] = 0;
(d[L_PDGFR]/dt)/d[tot_MKP1] = 0;
(d[L_PDGFR]/dt)/d[MKP_2] = 0;
(d[L_PDGFR]/dt)/d[Sos_a_Grb2] = 0;
(d[L_PDGFR]/dt)/d[Grb2] = 0;
(d[L_PDGFR]/dt)/d[Sos_Grb2] = 0;
(d[L_PDGFR]/dt)/d[Sos_a] = 0;
(d[L_PDGFR]/dt)/d[Sos] = 0;
(d[L_PDGFR]/dt)/d[PKC_Ca] = 0;
(d[L_PDGFR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[L_PDGFR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[L_PDGFR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[L_PDGFR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[L_PDGFR]/dt)/d[PKC_basal_a] = 0;
(d[L_PDGFR]/dt)/d[PKC_AA_a] = 0;
(d[L_PDGFR]/dt)/d[PKC_Ca_DAG] = 0;
(d[L_PDGFR]/dt)/d[PKC_DAG] = 0;
(d[L_PDGFR]/dt)/d[PKC_DAG_AA] = 0;
(d[L_PDGFR]/dt)/d[PKC_cytosolic] = 0;
(d[L_PDGFR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[L_PDGFR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_RGR] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_ser_RGR] = 0;
(d[L_PDGFR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[L_PDGFR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[L_PDGFR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[craf_1] = 0;
(d[L_PDGFR]/dt)/d[craf_1_a] = 0;
(d[L_PDGFR]/dt)/d[MAPKK] = 0;
(d[L_PDGFR]/dt)/d[MAPK] = 0;
(d[L_PDGFR]/dt)/d[craf_1_a_a] = 0;
(d[L_PDGFR]/dt)/d[MAPK_tyr] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_a] = 0;
(d[L_PDGFR]/dt)/d[MAPKK_ser] = 0;
(d[L_PDGFR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[L_PDGFR]/dt)/d[RGR] = 0;
(d[L_PDGFR]/dt)/d[Ubiquitination] = 0;
(d[L_PDGFR]/dt)/d[MKP_1_ser359_a] = 0;
(d[L_PDGFR]/dt)/d[MKP_1_a_a] = 0;
(d[L_PDGFR]/dt)/d[nuc_MAPK_a] = 0;
(d[L_PDGFR]/dt)/d[MKP1_RNA] = 0;
(d[L_PDGFR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[L_PDGFR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[L_PDGFR]/dt)/d[PLA2_cytosolic] = 0;
(d[L_PDGFR]/dt)/d[PLA2_Ca_a] = 0;
(d[L_PDGFR]/dt)/d[PIP2_PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[PLA2_a_Ca] = 0;
(d[L_PDGFR]/dt)/d[PLA2_a] = 0;
(d[L_PDGFR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[L_PDGFR]/dt)/d[GTP_Ras_GAP] = 0;
(d[L_PDGFR]/dt)/d[inact_GEF] = 0;
(d[L_PDGFR]/dt)/d[GEF_a] = 0;
(d[L_PDGFR]/dt)/d[GTP_Ras] = 0;
(d[L_PDGFR]/dt)/d[GDP_Ras] = 0;
(d[L_PDGFR]/dt)/d[GAP_a] = 0;
(d[L_PDGFR]/dt)/d[GAP] = 0;
(d[L_PDGFR]/dt)/d[SHC_L_PDGFR] = --0.2 + 0.05;
(d[L_PDGFR]/dt)/d[PDGFR] = 200 * piecewise(geq(time, 300), 0, 0.0015);
(d[L_PDGFR]/dt)/d[L_PDGFR] = -0.1 - 0.001 - 0.3 * SHC;
(d[L_PDGFR]/dt)/d[SHC] = -(0.3 * L_PDGFR);
(d[L_PDGFR]/dt)/d[SHC_a] = 0;
(d[L_PDGFR]/dt)/d[Internal_L_PDGFR] = --0.00066;
# SHC:
(d[SHC]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[SHC]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[SHC]/dt)/d[GAP_PKC_a_pool] = 0;
(d[SHC]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[SHC]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[SHC]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[SHC]/dt)/d[MKP_1_MAPK_a] = 0;
(d[SHC]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[SHC]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[SHC]/dt)/d[MAPK_a_MKP_1] = 0;
(d[SHC]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[SHC]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[SHC]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[SHC]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[SHC]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[SHC]/dt)/d[MAPK_a_MKP_2] = 0;
(d[SHC]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[SHC]/dt)/d[AA] = 0;
(d[SHC]/dt)/d[MAPK_a] = 0;
(d[SHC]/dt)/d[MKP_1] = 0;
(d[SHC]/dt)/d[PPhosphatase2A] = 0;
(d[SHC]/dt)/d[tot_MKP1] = 0;
(d[SHC]/dt)/d[MKP_2] = 0;
(d[SHC]/dt)/d[Sos_a_Grb2] = 0;
(d[SHC]/dt)/d[Grb2] = 0;
(d[SHC]/dt)/d[Sos_Grb2] = 0;
(d[SHC]/dt)/d[Sos_a] = 0;
(d[SHC]/dt)/d[Sos] = 0;
(d[SHC]/dt)/d[PKC_Ca] = 0;
(d[SHC]/dt)/d[PKC_DAG_AA_a] = 0;
(d[SHC]/dt)/d[PKC_Ca_AA_a] = 0;
(d[SHC]/dt)/d[PKC_Ca_memb_a] = 0;
(d[SHC]/dt)/d[PKC_DAG_memb_a] = 0;
(d[SHC]/dt)/d[PKC_basal_a] = 0;
(d[SHC]/dt)/d[PKC_AA_a] = 0;
(d[SHC]/dt)/d[PKC_Ca_DAG] = 0;
(d[SHC]/dt)/d[PKC_DAG] = 0;
(d[SHC]/dt)/d[PKC_DAG_AA] = 0;
(d[SHC]/dt)/d[PKC_cytosolic] = 0;
(d[SHC]/dt)/d[MAPK_MAPKK_a] = 0;
(d[SHC]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[SHC]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[SHC]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[SHC]/dt)/d[MAPKK_RGR] = 0;
(d[SHC]/dt)/d[MAPKK_ser_RGR] = 0;
(d[SHC]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[SHC]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[SHC]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[SHC]/dt)/d[craf_1] = 0;
(d[SHC]/dt)/d[craf_1_a] = 0;
(d[SHC]/dt)/d[MAPKK] = 0;
(d[SHC]/dt)/d[MAPK] = 0;
(d[SHC]/dt)/d[craf_1_a_a] = 0;
(d[SHC]/dt)/d[MAPK_tyr] = 0;
(d[SHC]/dt)/d[MAPKK_a] = 0;
(d[SHC]/dt)/d[MAPKK_ser] = 0;
(d[SHC]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[SHC]/dt)/d[RGR] = 0;
(d[SHC]/dt)/d[Ubiquitination] = 0;
(d[SHC]/dt)/d[MKP_1_ser359_a] = 0;
(d[SHC]/dt)/d[MKP_1_a_a] = 0;
(d[SHC]/dt)/d[nuc_MAPK_a] = 0;
(d[SHC]/dt)/d[MKP1_RNA] = 0;
(d[SHC]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[SHC]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[SHC]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[SHC]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[SHC]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[SHC]/dt)/d[PLA2_cytosolic] = 0;
(d[SHC]/dt)/d[PLA2_Ca_a] = 0;
(d[SHC]/dt)/d[PIP2_PLA2_a] = 0;
(d[SHC]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[SHC]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[SHC]/dt)/d[PLA2_a_Ca] = 0;
(d[SHC]/dt)/d[PLA2_a] = 0;
(d[SHC]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[SHC]/dt)/d[GTP_Ras_GAP] = 0;
(d[SHC]/dt)/d[inact_GEF] = 0;
(d[SHC]/dt)/d[GEF_a] = 0;
(d[SHC]/dt)/d[GTP_Ras] = 0;
(d[SHC]/dt)/d[GDP_Ras] = 0;
(d[SHC]/dt)/d[GAP_a] = 0;
(d[SHC]/dt)/d[GAP] = 0;
(d[SHC]/dt)/d[SHC_L_PDGFR] = --0.2;
(d[SHC]/dt)/d[PDGFR] = 0;
(d[SHC]/dt)/d[L_PDGFR] = -(0.3 * SHC);
(d[SHC]/dt)/d[SHC] = -(0.3 * L_PDGFR);
(d[SHC]/dt)/d[SHC_a] = 0.01;
(d[SHC]/dt)/d[Internal_L_PDGFR] = 0;
# SHC_a:
(d[SHC_a]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[SHC_a]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[SHC_a]/dt)/d[GAP_PKC_a_pool] = 0;
(d[SHC_a]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[SHC_a]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[SHC_a]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[SHC_a]/dt)/d[MKP_1_MAPK_a] = 0;
(d[SHC_a]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[SHC_a]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[SHC_a]/dt)/d[MAPK_a_MKP_1] = 0;
(d[SHC_a]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[SHC_a]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[SHC_a]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[SHC_a]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[SHC_a]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[SHC_a]/dt)/d[MAPK_a_MKP_2] = 0;
(d[SHC_a]/dt)/d[Shc_a_Sos_Grb2] = 0.1;
(d[SHC_a]/dt)/d[AA] = 0;
(d[SHC_a]/dt)/d[MAPK_a] = 0;
(d[SHC_a]/dt)/d[MKP_1] = 0;
(d[SHC_a]/dt)/d[PPhosphatase2A] = 0;
(d[SHC_a]/dt)/d[tot_MKP1] = 0;
(d[SHC_a]/dt)/d[MKP_2] = 0;
(d[SHC_a]/dt)/d[Sos_a_Grb2] = 0;
(d[SHC_a]/dt)/d[Grb2] = 0;
(d[SHC_a]/dt)/d[Sos_Grb2] = -(0.49998 * SHC_a);
(d[SHC_a]/dt)/d[Sos_a] = 0;
(d[SHC_a]/dt)/d[Sos] = 0;
(d[SHC_a]/dt)/d[PKC_Ca] = 0;
(d[SHC_a]/dt)/d[PKC_DAG_AA_a] = 0;
(d[SHC_a]/dt)/d[PKC_Ca_AA_a] = 0;
(d[SHC_a]/dt)/d[PKC_Ca_memb_a] = 0;
(d[SHC_a]/dt)/d[PKC_DAG_memb_a] = 0;
(d[SHC_a]/dt)/d[PKC_basal_a] = 0;
(d[SHC_a]/dt)/d[PKC_AA_a] = 0;
(d[SHC_a]/dt)/d[PKC_Ca_DAG] = 0;
(d[SHC_a]/dt)/d[PKC_DAG] = 0;
(d[SHC_a]/dt)/d[PKC_DAG_AA] = 0;
(d[SHC_a]/dt)/d[PKC_cytosolic] = 0;
(d[SHC_a]/dt)/d[MAPK_MAPKK_a] = 0;
(d[SHC_a]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[SHC_a]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[SHC_a]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[SHC_a]/dt)/d[MAPKK_RGR] = 0;
(d[SHC_a]/dt)/d[MAPKK_ser_RGR] = 0;
(d[SHC_a]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[SHC_a]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[SHC_a]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[SHC_a]/dt)/d[craf_1] = 0;
(d[SHC_a]/dt)/d[craf_1_a] = 0;
(d[SHC_a]/dt)/d[MAPKK] = 0;
(d[SHC_a]/dt)/d[MAPK] = 0;
(d[SHC_a]/dt)/d[craf_1_a_a] = 0;
(d[SHC_a]/dt)/d[MAPK_tyr] = 0;
(d[SHC_a]/dt)/d[MAPKK_a] = 0;
(d[SHC_a]/dt)/d[MAPKK_ser] = 0;
(d[SHC_a]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[SHC_a]/dt)/d[RGR] = 0;
(d[SHC_a]/dt)/d[Ubiquitination] = 0;
(d[SHC_a]/dt)/d[MKP_1_ser359_a] = 0;
(d[SHC_a]/dt)/d[MKP_1_a_a] = 0;
(d[SHC_a]/dt)/d[nuc_MAPK_a] = 0;
(d[SHC_a]/dt)/d[MKP1_RNA] = 0;
(d[SHC_a]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[SHC_a]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[SHC_a]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[SHC_a]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[SHC_a]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[SHC_a]/dt)/d[PLA2_cytosolic] = 0;
(d[SHC_a]/dt)/d[PLA2_Ca_a] = 0;
(d[SHC_a]/dt)/d[PIP2_PLA2_a] = 0;
(d[SHC_a]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[SHC_a]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[SHC_a]/dt)/d[PLA2_a_Ca] = 0;
(d[SHC_a]/dt)/d[PLA2_a] = 0;
(d[SHC_a]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[SHC_a]/dt)/d[GTP_Ras_GAP] = 0;
(d[SHC_a]/dt)/d[inact_GEF] = 0;
(d[SHC_a]/dt)/d[GEF_a] = 0;
(d[SHC_a]/dt)/d[GTP_Ras] = 0;
(d[SHC_a]/dt)/d[GDP_Ras] = 0;
(d[SHC_a]/dt)/d[GAP_a] = 0;
(d[SHC_a]/dt)/d[GAP] = 0;
(d[SHC_a]/dt)/d[SHC_L_PDGFR] = 0.05;
(d[SHC_a]/dt)/d[PDGFR] = 0;
(d[SHC_a]/dt)/d[L_PDGFR] = 0;
(d[SHC_a]/dt)/d[SHC] = 0;
(d[SHC_a]/dt)/d[SHC_a] = -(0.49998 * Sos_Grb2) - 0.01;
(d[SHC_a]/dt)/d[Internal_L_PDGFR] = 0;
# Internal_L_PDGFR:
(d[Internal_L_PDGFR]/dt)/d[GDP_Ras_Shc_a_Sos_Grb2] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1_PKC_a_pool] = 0;
(d[Internal_L_PDGFR]/dt)/d[GAP_PKC_a_pool] = 0;
(d[Internal_L_PDGFR]/dt)/d[inact_GEF_PKC_a_pool] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1_a_MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PLA2_cytosolic_MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP_1_MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP_1_ser359_a_MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_tyr_MKP_1] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_a_MKP_1] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1_a_PPhosphatase2A] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_a_PPhosphatase2A] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_ser_PPhosphatase2A] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1_a_a_PPhosphatase2A] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_tyr_MKP_2] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_a_MKP_2] = 0;
(d[Internal_L_PDGFR]/dt)/d[Shc_a_Sos_Grb2] = 0;
(d[Internal_L_PDGFR]/dt)/d[AA] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP_1] = 0;
(d[Internal_L_PDGFR]/dt)/d[PPhosphatase2A] = 0;
(d[Internal_L_PDGFR]/dt)/d[tot_MKP1] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP_2] = 0;
(d[Internal_L_PDGFR]/dt)/d[Sos_a_Grb2] = 0;
(d[Internal_L_PDGFR]/dt)/d[Grb2] = 0;
(d[Internal_L_PDGFR]/dt)/d[Sos_Grb2] = 0;
(d[Internal_L_PDGFR]/dt)/d[Sos_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[Sos] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_Ca] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_DAG_AA_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_Ca_AA_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_Ca_memb_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_DAG_memb_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_basal_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_AA_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_Ca_DAG] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_DAG] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_DAG_AA] = 0;
(d[Internal_L_PDGFR]/dt)/d[PKC_cytosolic] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_MAPKK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_tyr_MAPKK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_Raf_GTP_Ras_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_ser_Raf_GTP_Ras_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_RGR] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_ser_RGR] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_tyr_MKP_1_a_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_a_MKP_1_a_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[Nucleotides_nuc_MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK] = 0;
(d[Internal_L_PDGFR]/dt)/d[craf_1_a_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPK_tyr] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MAPKK_ser] = 0;
(d[Internal_L_PDGFR]/dt)/d[Raf_GTP_Ras_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[RGR] = 0;
(d[Internal_L_PDGFR]/dt)/d[Ubiquitination] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP_1_ser359_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP_1_a_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[nuc_MAPK_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[MKP1_RNA] = 0;
(d[Internal_L_PDGFR]/dt)/d[APC_PLA2_Ca_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[APC_PIP2_PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[APC_PIP2_Ca_PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[APC_DAG_Ca_PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[APC_PLA2_a_Ca] = 0;
(d[Internal_L_PDGFR]/dt)/d[PLA2_cytosolic] = 0;
(d[Internal_L_PDGFR]/dt)/d[PLA2_Ca_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PIP2_PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PIP2_Ca_PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[DAG_Ca_PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[PLA2_a_Ca] = 0;
(d[Internal_L_PDGFR]/dt)/d[PLA2_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[GDP_Ras_GEF_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[GTP_Ras_GAP] = 0;
(d[Internal_L_PDGFR]/dt)/d[inact_GEF] = 0;
(d[Internal_L_PDGFR]/dt)/d[GEF_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[GTP_Ras] = 0;
(d[Internal_L_PDGFR]/dt)/d[GDP_Ras] = 0;
(d[Internal_L_PDGFR]/dt)/d[GAP_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[GAP] = 0;
(d[Internal_L_PDGFR]/dt)/d[SHC_L_PDGFR] = 0;
(d[Internal_L_PDGFR]/dt)/d[PDGFR] = 0;
(d[Internal_L_PDGFR]/dt)/d[L_PDGFR] = 0.001;
(d[Internal_L_PDGFR]/dt)/d[SHC] = 0;
(d[Internal_L_PDGFR]/dt)/d[SHC_a] = 0;
(d[Internal_L_PDGFR]/dt)/d[Internal_L_PDGFR] = -0.00066;