The ViennaRNA Package

Predict, analyze, compare and design RNA secondary structures

The ViennaRNA Package offers a comprehensive collection of algorithms dedicated to RNA secondary structures. Physics based RNA secondary structure prediction is at the heart of the package. It allows for the prediction of stable structures and structural ensembles, to compute thermodynamic probabilities, such as for base-pairs, to compare alternative folds, and to design RNA sequences that preferentially fold into a particular structure.

For individual analyses, automated workflows, or the development of new methods, our software provides both, ready-to-use Command-Line Tools and an API for C, Python and Perl (see RNAlib User Guide).

Get Started

New to the ViennaRNA Package? Find download and install instructions as well as steps to customize the builds for your requirements here.

To the Installation Guide

User Guides and Tutorials

• Command-Line Tools

• Tutorials

• I/O Formats

• RNAlib User Guide

To the User Guides

API Reference

Want to learn more about specific RNAlib functions? The reference guide contains a detailed description of the RNAlib API.

To the API reference

Contribute

Found a bug in our programs? Want to extend an existing implementation? Our contributors guide shows how to improve the ViennaRNA Package.

To the Contributors Guide