TBI-Preprint 05-03-001
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Titel:
CelloS: a Multi-level Approach to Evolutionary Dynamics
Author(s):
Camille Stephan-Otto Attolini,
Peter F. Stadler,
Christoph Flamm
Appeared in:
Proc. 8th ECAL, LNAI 3630, pp. 500-509, 2005
Abstract:
We study the evolution of simple cells that are equipped with a genome, a
rudimentary gene regulation network at transcription level and two classes
of functional genes: motion effectors allow the cell to move in response to
nutrient gradients while nutrient importers are required to actually feed
from the environment. The model is inspired by the protist Naegleria
gruberi which can switch between a feeding and dividing amoeboid state
and a mobile flagellate state depending on environmental conditions.
Simulation results demonstrate how selection in a variable environment
affects the gene number and efficiency so that the cells can rapidly switch
from one expression regime to the other depending on the external
conditions.
Keywords:
Artificial Cells,
gene regulation,
evolution,
Naegleria gruberi
Alternative Numbers:
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Last modified: 2005-09-14 16:52:19 xtof