93-06-043
Abstract:
Statistics of RNA Melting Kinectics
Manfred Tacker, Walter Fontana, Peter F. Stadler, and Peter Schuster
We present and study the behavior of a simple kinetic model for the melting of
RNA secondary structures, given that those structures are known. The model is
then used as a map that assigns structure dependent overall rate constants of
melting (or refolding) to a sequence. This induces a ``landscape'' of reaction
rates, or activation energies, over the space of sequences with fixed length.
We study the distribution and the correlation structure of these activation
energies.
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