@article{Tafer:2008, title={The impact of target site accessibility on the design of effective {siRNAs}.}, volume={26}, url={http://dx.doi.org/10.1038/nbt1404}, number={5}, journal={Nature Biotechnology}, publisher={Nature Publishing Group}, author={Tafer, Hakim and Ameres, Stefan L and Obernosterer, Gregor and Gebeshuber, Christoph A and Schroeder, R. and Martinez, Javier and Hofacker, Ivo L}, year={2008}, pages={578--583}}