RNAxs

siRNA design

RNAxs (Tafer et al., 2008) will help you to design potent siRNAs to knock down your gene(s) of interest. RNAxs is based on the RNAplfold program to assess the mRNA target site accessibility. RNAxs was trained on two different datasets, one targeting 3’UTRs and the other one designed to repress coding sequences only.

References

2008

  1. journal-article
    The impact of target site accessibility on the design of effective siRNAs
    Hakim Tafer, Stefan L Ameres, Gregor Obernosterer, and 4 more authors
    Nature Biotechnology, 2008
    DOI