RNAz (Washietl et al., 2005), (Hofacker et al., 2002) detects functional RNA secondary structures in multiple sequence alignment based on two characteristic features: (i) thermodynamic stability, (ii) structural conservation.
References
2005
-
Fast and reliable prediction of noncoding RNAs
Stefan
Washietl, Ivo L.
Hofacker, and Peter F.
Stadler
Proceedings of the National Academy of Sciences, 2005
2002
-
Secondary Structure Prediction for Aligned RNA Sequences
Ivo L.
Hofacker, Martin
Fekete, and Peter F.
Stadler
Journal of Molecular Biology, 2002